|
|
The Growth of vascular and skin cells on polymer materials for tissue engineering
Bačáková, Markéta ; Bačáková, Lucie (advisor) ; Smetana, Karel (referee) ; Daniel, Matej (referee)
The ideal vascular or skin substitute is able to simulate the functions of original vascular or skin tissue. To reach this goal, the tissue substitute should be based on a biomaterial scaffold of an appropriate structure and desirable physical and chemical properties. These properties strongly influence successful implantation of the substitute to the patient's organism, substitute durability in the organism, and the desired colonization of the scaffolds with cells. These properties have a great impact on the adhesion, proliferation, differentiation, and desired phenotypic maturation of cells. Most of the biomaterials used for constructing clinically used tissue substitutes do not have appropriate properties for sufficient cell colonization, and thus their surface modification is needed. This thesis focuses on the improvement of biomaterial surface properties for successful cell colonization by plasma treatment, or by grafting and coating biomaterials with bioactive substances and extracellular matrix proteins. The modification of polyethylene (PE) foils by Ar+ plasma discharge showed a positive effect on the spreading, proliferation, and phenotypic maturation of vascular smooth muscle cells (VSMC). Subsequent grafting of the plasma-activated surface with bioactive substances further influenced cell...
|
|
|
Inclusive Practice in Education of Refugee Children
Bačáková, Markéta ; Květoňová, Lea (advisor) ; Šotolová, Eva (referee) ; Šiklová, Jiřina (referee)
TITLE: Inclusive Practice in Education of Refugee Children AUTHOR: Markéta Bačáková DEPARTMENT: Department of Special Education Research in refugee education is currently almost non-existent in the Czech Republic, even though internationally, it represents a topic much researched and debated. Its importance lies within the high vulnerability of persons fleeing their homes due to persecution as well as within the area of human rights enshrined in many international conventions together with the current educational trends, such as the inclusive education. Moreover, international research shows that refugee children provide us with an utmost unique view on the education system. Listening to their voices, therefore, has the potential to help us find new answers for the ever-increasing diversity in school population. The presented doctoral project aims to support the discussion in the area of educational experiences of refugee children in the Czech Republic and simultaneously, to reflect the practice of countries with long experience with international migration. The thesis builds on a case study of a group of resettled Burmese refugees in the Czech Republic and poses the question whether these children and their families have the possibility to fully enjoy the right to education embedded in many...
|
guest ::
RSS feed.