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The Model of Financial Compensation for placement of a Deep Geological Repository of Radioactive Waste in the Czech republic in period from 2010 to 2016
Englerová, Anna ; Zeman, Martin (advisor) ; Vebrová, Ludmila (referee)
Author examines a way of allocation of governmental financial resources to municipalities in locations preselected for deep geological repository. She is searching for a way how to add a motivational incentive to the process of allocation of financial resources in order to improve municipalities attitude towards deep geological repository. Hypothesis, examined in this thesis, contains two related questions. It is assumed that (1) amount and structure of financial resources can significantly affect municipalities decision making and also that (2) current mechanism of allocation of compensations is ineffective and does not create sufficient incentives. Currently (end of the year 2016), negotiations between government and municipalities are in crisis despite significant financial compensation from government nuclear account to the municipalities. This thesis have potential to change municipalities negative stance on deep geological repository through motivational model of resource allocation. Theoretical part reviews basic economic background and introduces historical, sociological, technological and economic views of radioactivity and deep geological repository. In practical part author analyzes socio-economic situation, compares evolution of transfers from government to municipalities with their attitude towards deep geological repository in time and shows that current system of resource allocation does not motivate the municipalities to change their stance on deep geological repository. That confirms second part of our hypothesis. Author also proposes a motivational model of resource alllocation. She confirms its viability by comparing it with similar models from other countries, by surveying mayors of concerned municipalities and also by examining experts opinion. Verification of the model confirmed its motivational effect. By that, first assumption of our hypothesis, that structure of resource allocation can significantly affect municipalities decision making, was confirmed.
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Comparison of sequence variations in genes of biotransfromation enzymes in some carcinoma
Turková, Lucie ; Tavandzis, Spiros (referee) ; Bóday, Arpád (advisor)
Xenobiotic biotransformation process and its capacity is crucial for xenobiotic chemicals elimination that may cause damage toward cell structures. The effectiveness of the enzymes included in this process depends on the gene variants that encodes them. The aim of this work was to compare certain polymorphisms of selected genes between cases and control groups. Studied polymorphisms were null genotypes of the glutathione S-transferase gene M1 and T1 and the insertion of TA dinucleotide in the promotor region of UDP-glucuronosyl transferase 1A1. The number of cases group was six included patients with colorectal, lung, prostate, breast, pancreatic and head and neck cancer. Total number of analysed individuals was 1 118 for cancer cases and 470 for healthy controls. The control group was divided into two groups, the first one was called general and the second one was called special included healthy individuals with no cancer history in their closest family members. Gilbert syndrome (GS) is caused by homozygous insertion of the TA dinucleotide in the TATA box of the gene UGT1A1 and it causes elevated bilirubin levels. Bilirubin is a potent antioxidant in human body, so the aim was to attest its protective effect toward cancer. We expected lower frequency of GS as a protective factor in the cases groups compared with controls. This hypothesis was confirmed in the breast cancer group (GS frequency 10,0 %) and pancreatic cancer group (GS frequency 11,1 %). In the general and special control groups the frequency of GS was 16,0 % and 15,4 % respectively. Although the other case groups show lower frequency of GS, the results weren´t statistically significant. Null GSTM1 genotype was observed with 50,4 % frequency in the general control groups and with 55,3 % frequency in the special control group. Neither the one of the cases groups hasn´t showed significantly lower percentage of null genotype. Despite expectation we observed statistically significant lower frequency of null genotype in the group of lung and pancreatic cancer group (37,4 % and 39,3 % respectively). According to this study, we can say that the lack of glutathione S-transferase M1 activity is not a risk factor for cancer development. Null genotype of GSTT1 wasn´t identified in both control groups at all. In case groups of breast and prostate cancer, there was only one individual carrying the null GSTT1 genotype. Statistically significant higher frequency of this polymorphism was observed in patients with colorectal cancer (9,7 %), lung cancer (17,2 %), pancreatic cancer (3,0 %) and head and neck cancer (15,9 %). In these groups the lack of glutathion S-transferase T1 activity might be considered as risk factor for cancer development. Nevertheless, for further verification it needs to take more investigation in this field, especially enlarge the number of patient in the case groups of head and neck, lung and pancreatic cancer.
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Propagation of inclined cracks to the interface of ceramic laminates
Novotná, Lenka ; Trunec, Martin (referee) ; Chlup, Zdeněk (advisor)
Composite materials with laminated structure provide advantages which are utilised during component design. Low density, temperature and chemical stability are the profitable properties predetermining application of ceramic laminates. The main obstacle for wide spread of ceramic materials is their inherent brittleness. Therefore, in this thesis, the crack propagation in ceramics laminates has been extensively studied. Laminated structures with various volume fractions of components (alumina and zirconia) were prepared by electrophoretic deposition. Evaluation of crack propagation through the interface and determination of basic mechanical properties was conducted on the basis of extensive literature search. Crack deflection originated in both presence of internal stresses and differences in elastic modulus during the crack interface passing was monitored. A special type of specimen geometry was employed with the aim to set arbitrary angle between crack and interface. It was experimentally found that the degree of crack deflection is dependent on entering angle and volume fraction of components. Higher crack deflection was already found in the bulk of the test piece comparing to the test piece surface. The 3D fracture surface reconstruction generated using laser confocal microscopy was used in this detailed crack propagation study. Further basic elastic and strength characteristics of laminates were determined and compared to those obtained from monolithic materials. The validity of the mix rule for elastic characteristics was confirmed by comparing of elastics modulus. The most reliable method for elastic modulus determination was marked the dynamic resonance method due to low scatter and consistency in measurement. The flexural strength of all laminates tends to be close to the flexural strength of the weakest component. Therefore the mix rule is not applicable for flexural strength estimation on the contrary of elastic characteristics. The change of component volume fraction leads only to change of flexural strength scatter. Thanks to gained knowledge about crack propagation and basic characteristic determination will be possible to design ceramic laminates more efficiently for given needs of application.
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The marked word-order in Italian and its Czech translations.
BUZKOVÁ, Aneta
This diploma thesis deals with the marked word order in Italian and its translation into Czech. The work is divided into two parts. In the opening of the first, theoretical one the author applies her mind to the development of the linguistic attitude to the word order. The author focuses on the description of the basic parameters of the Czech and Italian word order with respect to the marked structures. The second, analytical part works with the selected examples of the Italian marked word order and its translation into Czech. The comparative examples of word order in the analytical part are chosen from the spoken corpus, fictional text and the parallel corpus InterCorp. The aim of this thesis is firstly comparing the Italian marked word order to the Czech one and secondly mapping general principles of translations into Czech. Conclusions and recommendations are drawn for translation into Czech.
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Influence of a particullar heat on properties and structure of duplex steel welded joint
Němec, Karel ; Kubíček, Jaroslav (referee) ; Daněk, Ladislav (advisor)
The research project is focused on an influence of a particullar heat on properties and structure of duplex steel DIN 1.4462. Samples prepared by using different welding speeds 10, 15, 20, 25, 30 cm.min-1, were tested for tensile, metalographical analysis and hardness test. Experimental results proved the optimal welding speed for material with 2 mm thickness to be 15 cm.min-1. Usage of lower speed 10 cm.min-1 led to formation of hot cracks while higher speeds 20, 25, 30 cm.min-1 didn‘t cause material penetration.
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Numeric simulation welding of the turbine vane and rotor
Dohnal, Ivo ; Slováček, Marek (referee) ; Daněk, Ladislav (advisor)
Numeric simulation welding of the turbine vane and rotor - master’s thesis is ordered by the Siemens Industrial Turbomachinery ltd. company. Simulation welding is done in program SYSWELD. Used welding materials are X22CrMoV12-1 (turbine vane), 30CrMoNiV5-11 (rotor), TOPCORE 838 B (additional material). These are temperature-resistant and fire-resistant welding materials. The SYSWELD program works on the principle of finite elements method. By SYSWELD is done the evaluation of temperature and stress fields and material structure after welding. Here is a part , which deals with computations of welding crevices.
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Determination of municipal fire protection units in the territory of South Bohemia region to perform task in the field of protection of population.
ŘIMNÁČ, Jiří
In order to preserve its existence since its origination, mankind has had to deal with a variety of adverse effects which have been largely influencing human conduct and behaviour. We become witnesses to events that are identified as exceptional, because they often occur unexpectedly and endanger the lives and health of people. These events cause great damage to property and the environment. They may arise from harmful reactions of forces and phenomena resulting from human activities, from natural forces or from a combination of both. Such events may be floodings, storms, technological accidents with the release of hazardous substances, major road accidents, extensive fires, acts of terrorism. The management of such incidents and emergencies requires the intervention of the Integrated Rescue System. The joint intervention of the components abides by legal standards and internal guidelines. During the intervention of the Integrated Rescue System, a crucial part of the activities is carried out by the Fire and Rescue Units. The diploma thesis deals with the legislation in the field of civil protection and population protection. Information on the history of civil protection and population protection tasks is provided. The administrative territory of the South Bohemian region is characterized. The issue of the Integrated Rescue System and its structure is dealt with. The Fire and Rescue Units are proposed as appropriate to protect the population.
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