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Image processing software for infrared thermography study during radio frequency ablation
Zemčíková, Petra ; Sedlář, Martin (referee) ; Bernard, Vladan (advisor)
This thesis deals with principle and device of radiofrequency ablation technique, infrared imaging systems with a focus on non-contact measurement of surface temperatures, process of representation and detection of infrared radiation. On the next part of the thesis are described methods of image processing with an emphasis on the methods used in the software for processing infrared radiofrequency ablation images. The thesis also includes the design and the description of the created software for evaluating the effect of duration of ablation, used power or position of the electrodes and the stent to the stent heating.
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The application of thermography in endovascular surgery
Kyjovský, Ondřej ; Harabiš, Vratislav (referee) ; Rozman, Jiří (advisor)
The bachelor thesis deals with the using of thermography as a supporting diagnostic method for endovascular thermoablative treatment of varicose veins. The principle of IRT is the detection of infrared radiation. The main goal of this thesis is to compare how temperature of the area changes before the surgery, during the surgery, immediately after the surgery and in the postoperative period in the interval of one week in radio frequency induced thermotherapy (RFITT) and endovascular laser therapy (EVLT).
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Analysis of intracardiac electrogram, depending on transmurality of ablation lesions at catheter radiofrequency ablation of cardiac arrythmias
Žbánková, Alena ; Kozumplík, Jiří (referee) ; Kolářová, Jana (advisor)
Catheter ablation is a unique method for cardiac arrhythmias treatment based on creating spot lesions of radiofrequency energy using intracardiac ablation catheter. Transmurality of these lesions should be achieved for long-term therapeutic treatment effect. The degree of myocardial damage depth is reflected in the parameters of sensed intracardiac ECG. From research studies is evident that the change in morphology and deflection of ablation signal play a key role in the assessment of transmurality. This thesis consists of theoretical introduction to electrophysiology, proposal and realization of methods for objective assessment of transmurality by processing signals in time, frequency and time – frequency domain. The end of this diploma thesis includes the statistical analysis of these clinical dat and comparison of methods.
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Early esophageal neoplasia: etiology, pathophysiology, pathogenesis and treatment. Barrett's esophagus and early esophageal adenocarcinoma
Krajčíová, Jana ; Martínek, Jan (advisor) ; Dolina, Jiří (referee) ; Bureš, Jan (referee)
Background: Barrett's esophagus (BE) is a premalignant condition defined by replacement of normal esophageal squamous-cell epithelium by cylindrical epithelium with intestinal metaplasia (IM). Patients with BE associated neoplasia (BORN) are candidates for endoscopic treatment. The aims of our studies were: (1) analysis of long-term efficacy of radiofrequency ablation (RFA) and evaluation of risk factors for persistent/ recurrent neoplasia/ IM; (2) to assess the results and safety of confocal laser endomicroscopy (CLE) compared to standard biopsies in patients after successful endoscopic treatment of BORN; (3) to assess the sampling quality obtained by different types of forceps; and (4) to assess "de novo" reflux after peroral endoscopic myotomy (POEM) and its severity (the risk of development of further complications). Patients and methods: We performed a total of 4 studies. (1) In a retrospective RFA study we evaluated data of 136 patients treated endoscopically for BORN in 4 centers in the Czech Republic. (2) In a prospective, pathologist-blinded, CLE study, we evaluated concordance in the detection of IM or neoplasia with CLE compared to standard biopsies in 56 patients who underwent standard surveillance endoscopy. (3) In a prospective study comparing 4 types of forceps, we evaluated the...
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Experimental Use Of Novel Pulse Generator For Irreversible Electroporation
Novotná, Veronika
Irreversible electroporation (IRE) is a relatively new technique for minimal invasive nonthermal ablation treatment of solid tumors. This article describes basics of IRE and available devices for this technique. The parameters of commercial NanoKnife IRE generator are verified and the unique experimental IRE generator developed at the Brno University of Technology is presented in this paper. Further, there is a comparison of thermal effects on a target tissue of commonly used radiofrequency ablation (RFA) and the novel IRE generator using an infrared camera. All experiments were performed ex vivo on a porcine liver. The difference in maximum temperature between the output powers used was 17.8 °C with RFA and 3 °C with IRE. This is a significant difference and shows the IRE’s capability of liver tissue ablation without thermal damage. The new IRE generator is also capable of replacing NanoKnife because of its features and versatility.
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The Use Of Thermography In Endovascular Surgeries
Kyjovský, Ondřej
This article deals with the use of thermography as a support diagnostic method for the treatment of varicose veins. The principle of IRT involves the detection of infrared radiation. The main objective of the study was to compare how the temperature varies during the scanning procedure for RFA and EVLT, as well as the changing temperature of the surface of the skin before surgery and after surgery.
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Use the Contrast-Enhanced Ultrasoun in the Morning of the Effect of Liver Tumors Treatment by Radiofrequency ablation
Korčáková, Eva ; Mírka, Hynek (advisor) ; Mechl, Marek (referee) ; Čtvrtlík, Filip (referee)
Use the contrast-enhanced ultrasound in the monitoring of the effect of liver tumors treatment by radiofrequency ablation. Summary High quality imaging is crucial for the treatment of liver tumors by the percutaneous radiofrequency ablation. Imaging methods are used for planning, navigation of the intervention and monitoring after treatment. An early detection of residual tumor tissue or recurrence affect significantly the quality of life and life expectancy of the patients. Contrast enhanced ultrasound (CEUS) seems to be a suitable method for monitoring the locoregional treatment mainly because zero radiation impact on patient and allows the highly accurate real-time assessment of vascularization. The aim of my work was to verify the ability of CEUS to detect residual tumor tissue or tumor recurrence in the field of changes after radiofrequency ablation. We evaluated the group of 73 patients, who were treated by radiofrequency ablation (RFA) for liver cancer. CEUS reached in our group the overal sensitivity 77.27 %, and in the group of colorectal cancer metastases 83.33 %. We compared CEUS with results of computed tomography (CT), which is the most commonly used method for monitoring the treatment. CEUS and CT results are similar. Based on this study, the CEUS appears to be a suitable method for monitoring...
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The application of thermography in endovascular surgery
Kyjovský, Ondřej ; Harabiš, Vratislav (referee) ; Rozman, Jiří (advisor)
The bachelor thesis deals with the using of thermography as a supporting diagnostic method for endovascular thermoablative treatment of varicose veins. The principle of IRT is the detection of infrared radiation. The main goal of this thesis is to compare how temperature of the area changes before the surgery, during the surgery, immediately after the surgery and in the postoperative period in the interval of one week in radio frequency induced thermotherapy (RFITT) and endovascular laser therapy (EVLT).
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Image processing software for infrared thermography study during radio frequency ablation
Zemčíková, Petra ; Sedlář, Martin (referee) ; Bernard, Vladan (advisor)
This thesis deals with principle and device of radiofrequency ablation technique, infrared imaging systems with a focus on non-contact measurement of surface temperatures, process of representation and detection of infrared radiation. On the next part of the thesis are described methods of image processing with an emphasis on the methods used in the software for processing infrared radiofrequency ablation images. The thesis also includes the design and the description of the created software for evaluating the effect of duration of ablation, used power or position of the electrodes and the stent to the stent heating.
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Analysis of intracardiac electrogram, depending on transmurality of ablation lesions at catheter radiofrequency ablation of cardiac arrythmias
Žbánková, Alena ; Kozumplík, Jiří (referee) ; Kolářová, Jana (advisor)
Catheter ablation is a unique method for cardiac arrhythmias treatment based on creating spot lesions of radiofrequency energy using intracardiac ablation catheter. Transmurality of these lesions should be achieved for long-term therapeutic treatment effect. The degree of myocardial damage depth is reflected in the parameters of sensed intracardiac ECG. From research studies is evident that the change in morphology and deflection of ablation signal play a key role in the assessment of transmurality. This thesis consists of theoretical introduction to electrophysiology, proposal and realization of methods for objective assessment of transmurality by processing signals in time, frequency and time – frequency domain. The end of this diploma thesis includes the statistical analysis of these clinical dat and comparison of methods.
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