Original title: Experimental Use Of Novel Pulse Generator For Irreversible Electroporation
Authors: Novotná, Veronika
Document type: Papers
Language: eng
Publisher: Vysoké učení technické v Brně, Fakulta elektrotechniky a komunikačních technologií
Abstract: Irreversible electroporation (IRE) is a relatively new technique for minimal invasive nonthermal ablation treatment of solid tumors. This article describes basics of IRE and available devices for this technique. The parameters of commercial NanoKnife IRE generator are verified and the unique experimental IRE generator developed at the Brno University of Technology is presented in this paper. Further, there is a comparison of thermal effects on a target tissue of commonly used radiofrequency ablation (RFA) and the novel IRE generator using an infrared camera. All experiments were performed ex vivo on a porcine liver. The difference in maximum temperature between the output powers used was 17.8 °C with RFA and 3 °C with IRE. This is a significant difference and shows the IRE’s capability of liver tissue ablation without thermal damage. The new IRE generator is also capable of replacing NanoKnife because of its features and versatility.
Keywords: Development; Infrared camera; Irreversible Electroporation; Radiofrequency ablation
Host item entry: Proceedings of the 23st Conference STUDENT EEICT 2017, ISBN 978-80-214-5496-5

Institution: Brno University of Technology (web)
Document availability information: Fulltext is available in the Brno University of Technology Digital Library.
Original record: http://hdl.handle.net/11012/187167

Permalink: http://www.nusl.cz/ntk/nusl-414827


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Universities and colleges > Public universities > Brno University of Technology
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