National Repository of Grey Literature 43 records found  beginprevious34 - 43  jump to record: Search took 0.00 seconds. 
Analogues of Orn and DAP as potential inhibitors of bacterial enzymes ArgE and DapE
Hlaváček, Jan ; Pícha, Jan ; Vaněk, Václav ; Jiráček, Jiří ; Slaninová, Jiřina ; Fučík, Vladimír ; Gilner, D. ; Holc, R. C.
The series of ornithine and diaminopimelic acid derivatives were prepared. Some of the compounds are inhibitors of enzymes, which catalyze formation of bacterial precursors.
Nové inhibitory lidské betain-homocystein S-metyl transferázy
Jiráček, Jiří ; Collinsová, Michaela ; Rosenberg, Ivan ; Netušilová, Hana ; Buděšínský, Miloš ; Garrow, T. A.
We synthesized a series of homocysteine analogues with different substituents on sulfur. The IC50 of the most potent inhibitors is in nanomolar range.
ABEI-značené 2-5A: Způsob chemiluminiscenčního sledování vazebného procesu RNase L
Páv, Ondřej ; Protivínská, Eva ; Jiráček, Jiří ; Rosenberg, Ivan
As an alternative for radiolabeled ones, chemiluminescent ABEI-labeled 2-5A probe was synthesized and evaluated for its concentration-dependent detection limit.
Kapilární elektroforéza v silně kyselých základních elektrolytech a její užití pro separaci a charakterizaci peptidových a pseudopeptidových stereoizomerů
Kašička, Václav ; Koval, Dušan ; Šolínová, Veronika ; Sázelová, Petra ; Hlaváček, Jan ; Jiráček, Jiří
Capillary zone electrophoresis in the strongly acidic background electrolytes (pH range 1.1-3.2), has been applied for separation and physicochemical characterization of insect oostatic peptides and phosphinic pseudopeptides.
Separation of phosphinic pseudopeptide diastereomers by CZE and RP-HPLC
Koval, Dušan ; Kašička, Václav ; Jiráček, Jiří ; Collinsová, Michaela
Capillary zone electrophoresis (CZE) and reverse phase high-performance liquid chromatography (RP-HPLC) were used for separation of diastereomers of phosphinic pseudopeptides. The migration order in CZE with their elution order in RP-HPLC was compared.
Analysis and characterization of phosphinic pseudopeptides by capillary zone electrophoresis
Koval, Dušan ; Jiráček, Jiří ; Collinsová, Michaela ; Kašička, Václav
Phosphinic pseudopeptides of general structure N-Ac-Val-Ala.psi.(PO.sub.2./sub.-CH.sub.2./sub.)Leu-Xaa-NH.sub.2./sub., where Xaa represents one of 20 proteinogenic amino acid residues were studied. Separation of diastereomers of some peptides was achieved in acid electrolyte.
Development of novel inhibitors of Zn-metalloenzyme betaine: homocysteine .I.S./I.-methyltransferase
Collinsová, Michaela ; Castro, C. ; Garrow, T. ; Dive, V. ; Yiotakis, A. ; Jiráček, Jiří
New approach for the discovery of novel phosphinic pseudopeptide inhibitors of Zn-metalloenzyme betaine: homocysteine .I.S./I.-methyltransferase.
Fluorescent labeled amino acid utilizable in solid phase peptide synthesis
Ciencialová, Alice ; Klasová, Lenka ; Jiráček, Jiří ; Barthová, J. ; Barth, Tomislav
Synthesis of fluorescent derivatives of lysine fluorescent probes: 4-phenylspiro[furan-2(3.I.H./I.),1'-phthalan]-3,3'-dione (fluorescamine) and 4-chloro-7-nitrobenzo[1,2,5]oxadiazole (NBD-Cl) utilizable in solid phase peptide synthesis is presented.
Qualitative and quantitative microanalysis and preparative purification of biopeptides by capillary and continuous free-flow electrophoresis
Kašička, Václav ; Prusík, Zdeněk ; Sázelová, Petra ; Ježek, Jan ; Jiráček, Jiří ; Hlaváček, Jan ; Velek, Jiří ; Barth, Tomislav
High-performance capillary electrophoresis (HPCE) has been applied to qualitative and quantitative analysis of several biologically active peptides and their derivatives and fragments, e.g. insulins, insect oostatic hormones, and peptide and glycopeptide dendrimers.
Side reactions during photochemical cleavage of ŕ-methyl-6-nitroveratryl-based photolabile linker
Rinnová, Markéta ; Collinsová, Michaela ; Kašička, Václav ; Jiráček, Jiří
We have identified significant side reactions using ŕ-methyl-6-nitroveratryl-based photolinker for study of biological interactions.

National Repository of Grey Literature : 43 records found   beginprevious34 - 43  jump to record:
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2 Jiráček, Jakub
6 Jiráček, Jan
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