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Effect MTEP on immature rat behaviour.
Tichá, Kateřina ; Mareš, Pavel (advisor) ; Telenský, Petr (referee)
Metabotropic glutamate receptors represent prospective targets for anticonvulsant therapy of epilepsy. However there may be serious negative side effects. In this study the highly specific antagonist of mGluR5 was used - MTEP, [(2-methyl-1,3-thiazol-4-yl)ethynyl] pyridine, which was shown previously to have an anticonvulsant action. Our study was aimed at other possible effects, such as efficacy in motor skills, spontaneous behaviour, space learning and rate of anxiety. Animals, immature male Wistar rats (12, 18 and 25 days old), were pretreated with MTEP in two different doses - 20mg/kg and 40mg/kg, because MTEP demonstrated anticonvulsant activity in exactly such high doses. Animals were tested 15 min, 60 min and 24h (in elevated plus maze test only) after treatement. No negative effects were found in motor tests;, space learning in elevated plus maze was also not compromised. On the other hand, MTEP influenced frequency of some types of stereotypic behaviour in the open field test. MTEP exhibited anxiolytic-like effect in elevated plus maze in immature rats; this side effect has to be taken as a positive one. Powered by TCPDF (www.tcpdf.org)
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Translation with Commentary: Marr, Andrew: A History of Modern Britain
Tichá, Kateřina ; Šťastná, Zuzana (advisor) ; Tobrmanová, Šárka (referee)
The core of this bachelor's thesis is a translation of an extract from the book A History of Modern Britain by the British journalist Andrew Marr. The first part of this thesis consists of the translated text. The selected chapters are dealing with the situation in Britain at the turn of the millennium and the last years of the New Labour government. The second part consists of a commentary of the translation. There is an analysis of the original text in terms of the extratextual and intratextual factors, then typology of translation problems with examples of solutions, a summary of translation shifts and a description of the translation method.
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Volunteer's Experience with Senior
Tichá, Kateřina ; Spalová, Barbora (advisor) ; Göttlichová, Marcela (referee)
This bachelor thesis deals with the theme of volunteering in the lives of seniors. The main aim of the thesis is to clarify, how the volunteer himself can interpret his experience with seniors, which themes are important to him and what is the role of these experiences in his life. The text is divided into theoretical and practical parts. The first chapter of the theoretical part summarizes the current knowledge about aging, firstly in general and then specifically in the Czech Republic. The second chapter summarizes the current knowledge about volunteering and volunteer programs aimed at seniors in the Czech Republic. The practical part deals with the goals of research, used methodology and the process of the analysis. The most important part is the analysis itself and partial conclusions of each findings. Finally, I found four basic themes, which are important for volunteer experience. There are motivation of volunteers and reasons for volunteering, the reconstruction of volunteer experience with seniors, particular factors that volunteer considers as important during interpretation and consequences of volunteering activity in their personal lifes. The thesis is concluded by conclusion and summarization of key findings.
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Relationship of inhabitants to their home place in Eastern and Western Ore Mountains (Krušné hory)
Tichá, Kateřina ; Mikšíček, Petr (advisor) ; Braun Kohlová, Markéta (referee)
Diplomová práce Vztah obyvatel k místu 5 Abstract This thesis entitled "Relationship of inhabitants to their home place in Eastern and Western Ore Mountains (Krušné hory)" focuses on the issue of a relationship the current inhabitants have to the area they live in. This relationship is defined on the basis of several distinct theoretical areas. The first portion of the thesis covers the basic terminology key for understanding the relationship of inhabitants to their home place. It deals with the definition of the term "home place", its character and ways in which it may be perceived. It also contemplates the term "settlement" and focuses on "identity" which is further defined as biographical and regional identity. Identity may be studied in the context of a relationship to the countryside, local community and historical awareness. The paper also characterises the Sudetenland region and provides the historical context necessary for a comprehensive outlook at the area researched without marginalizing the issue of nationalism. The practical portion employs qualitative methodology to process eighteen semi-structured interviews with representatives of elites (mayors, businessmen and members of associations) of the selected are of the Eastern and Western Ore Mountains. Subsequent analyses point to identical and...
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Life before myocardial infarction
Tichá, Kateřina ; Votroubková, Michaela (advisor) ; Vlášková, Dana (referee)
Author: Kateřina Tichá Institution: Department of Social Medicine, Medical Faculty of Charles University in Hradec Králové, Department of Nursing Title: Life before myocardial infarction Supervisor: Mgr. Michaela Votroubková Number of pages: 68 Number of attachments: 3 Year of defense: 2012 Keywords: lieve, heart, ischemic heart disease, myocardial infarction, risk factors The bachelor thesis deals with patient's life style before suffering myocardial infarction within a few regions of the Czech Republic. It points out risk factors which can cause myocardial infarction. It emphasizes the difference between life style of women and men. The focus is created by quantitative research targeted on risk factors of cardio-vascular disease. The researched sample is created by patients who are hospitalized for acute myocardial infarction solved by percutaneous coronary intervention in regions Hradec Králové, Pardubice, Ústí nad Orlicí, Brno and Rychnov nad Kněžnou.
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Detached House Tichých
Tichá, Kateřina ; Lampa, Martin (referee) ; Smolka, Radim (advisor)
The subject of the bachelor thesis is a design documentation for detached house with a workshop. The object is situated in the South- Moravian region, in the city of Prštice. Detached house is designed as 6+kk and planned as a three-story building, with two above-ground floors and a basement. The workshop, which serves as a design office, is in the basement, with its own entrance from the west side of the plot. Besides of the design office, there is also toilet, and a bathroom in the workshop. Design office and family house are connected by a staircase. Main entrance of the family house is on the north side of the house. There is entrance for pedestrians and drive way to the garage as well. Entrance for pedestrians leads to wind lobby, from where is an entrance to the main hall and to the garage. There is staircase nearby main hall, which connects all floors. On the first floor there is a common part of the house with living room, kitchen and dining room. On the second floor there is a resting part of the house, with bedrooms for all family members and with a study. Vertical load-bearing structures are made from clay blocks. Horizontal load-bearing structures are composed from clay inserts and there is a mono pitched roof split into two parts. Above the garage, there is a walkable flat roof.
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Valuation of real estate for bank purposes
Tichá, Kateřina ; Bejšovec, Jaroslav (referee) ; Staněk, Roman (advisor)
The thesis is focused on analyzing the general practice appraiser or expert in the valuation of property for purposes of bank. Domestic banks for their own purposes require an estimate of a normal price. According to established procedures were estimated normal price of administrative building, located in the statutory city Havirov. To determine a normal price has been used three methods - cost method or material value, the comparison method and the yield method.
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Factas Influencing Usual Price of Real Estate
Tichá, Kateřina ; Bejšovec, Jaroslav (referee) ; Staněk, Roman (advisor)
This master´s thesis examines the factors that influence the usual price of real estate. The different types of real estate are different influences which it operates and also vary the intensity of their action. In addition to outlining the basic effects and intensity of exposure to various types of real estate work includes analysis of several influences – influences acting on apartments in major cities of our country influences in time for the usual price of apartments in Havirov and in Karvina, analyzing the factors that influence the amount of the usual price in selected locations of these cities, the impact of privatization of flats on the usual price of apartments in Karvina and size effect of floor space on the usual price of apartments.
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The issue of communication between the patient and nurse belonging to minority communities.
TICHÁ, Kateřina
The issue of cross-cultural nursing is currently a hot topic, because the tourism, migration, etc. grow due to the borders opening. The professionals working as paramedical staff are required to provide effective and high-quality nursing care to all people, without exception. But who considers the fact that the caring professionals can be a different culture, religion or nationality? The presented diploma thesis is devoted to nurses belonging to minority groups, and it is aimed to the problem of communication between the patient and the nurse belonging to a minority group. Specifically, this is about foreign-born nurses, nurses of different religions, same-sex orientation and nurses with physical disabilities. The theoretical basis on which the thesis relies, is primarily a conceptual model of nursing of the Rising Sun by Madeleine Leininger in interaction with the model of culturally considerate care by J. N. Giger and R. E. Davidhizar. In the theoretical part, the concepts relating to the cross-cultural nursing and issues relating to minority groups in the Czech Republic are defined. The preliminary descriptive empirical matter of the thesis was to find out what problems do nurses belonging to minority groups have in relation to the profession of nurses. Research sample is made up of 16 nurses belonging to minority groups, including nurses with different sexual orientation, physically disabled nurses, nurses with ethnic differences and the nurses of different religions. For the empirical part of the thesis, the qualitative approach was selected as a research design, since, according to Strauss and Corbin (1999), this option is appropriate in situations in which the researcher seeks to uncover the experience with a certain phenomenon. The introduction of the research investigation was a pilot study, which used the case study technique for data capture, specifically, the method of the life stories of nurses with cultural, religious, sexual or health differences. For the selection of the respondents there was the snowball method used, as we live in an area where there is difficult to reach these people. A pilot study was a base for the research investigation undertaken by using semi-structured interviews with patients, doctors and nurses in charge of the hospital. The results obtained in this survey were compared with the results of a pilot study. The main research objective of the pilot study was defined due to the research problem, to explore the issues of communication within the nursing care between the patient and the nurse belonging to a minority group. Following this target, the main research question was established: What problems do the nurses belonging to a minority group have to face in nursing practice? Then it is followed up with next research question: What difficulties do the nurses belonging to a minority group find in communication with a patient? The results of the pilot study are divided into 4 groups according to the above division, which means the nurses with different nationality, religion, with a different sexual orientation and handicapped nurses. In each group the areas of contact and interaction at the workplace were monitored, it means cooperation with colleagues, and the fact of the contact with patients from the perspective of the nurses and their personal subjective satisfaction of the communication held within the nursing profession. Subsequently, in the context of the pilot study, the occurrence of features typical only for certain groups of nurses was found out. From this point of view, for a group of nurses of foreign nationalities, the results included communication barriers associated with another native language than Czech. The research sample of disabled nurses expands the results for specific care procedures that may be a barrier due to their health-related handicaps. The nurses describe their physical difference and its circumstances.
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Nurse in the psychiatric ward as a source of confidence and trust for the mentally ill
TICHÁ, Kateřina
Mental diseases are often view as a taboo and stigmatizing phenomenon by the public eye. Similarly, the work of a nurse in a psychiatric ward is considered as unimportant in number of publications. The nurses, working in this department, are designated as unable to work in other departments. In the theoretical part, first is mentioned the current psychiatric care in the Czech Republic. Further, a history of psychiatric care is also mentioned. The largest chapter is created by providing the general definition of communication, its forms and specific of communication with the mentally sick patients. The theoretical work is concluded by a chapter devoted to ethics and law in psychiatry, and of course the nurse as a person takes also a well-deserved part in it. The aims of the dissertation thesis were four. The first objective was to determine whether the authority of the nurse is an integral part of the nursing process in the care of the mentally ill patients. Furthermore it was to determine whether nurses in the psychiatric ward strengthen their authority by compliance with communication policies and procedures. The penultimate goal was to find out in what nurses with experience in other fields of medicine see the most important differences in the requirements imposed on them in the implementation of the nursing process. The last goal was to find out whether nurses in the psychiatric ward know and follow the guidelines for communicating with the mentally ill persons. To these goals four research questions were set: Do nurses perceive the influence, which results from their authority,as a positive aspect of nursing care of patients in the psychiatric ward? Is the nurses' authority strengthened within their work with the mentally ill throughout the observance of the principles of communication? What are the most common differences in nursing care that the nurses see, which currently works in the psychiatric ward in comparison with other branches of medicine, where they acted in the past? Do nurses have the knowledge of the principles of communication with the patients and adherence to these principles, in a psychiatric ward? The research group consisted from four nurses for observation purposes and seven nurses for semi-standardized interviews in the Psychiatric ward at the hospital of Ceske Budejovice, j.s.c. The first part of the research works with the concept of authority. This research provided a result that the authority should not occur between nurses and patients, and moreover nurses themselves should aspire to be more a companion and a helper to a successful treatment and mental health care. All nurses rather talk about trust, which by their own words is obligatory for effective nursing care and communication with the client. Therefore, they always try to provide the patient with maximum acceptable form of information and so to minimize their fear from the unknown and often from their own illness. At the same time they require and pay attention to strict observance of the rules by patients, which in effect reinforces the sense of confidence. Everywhere in health care and when working with people the communication is important, but nurses say, that in the care of the mentally ill, especially in communication it is essential not to make mistakes. The research observation confirmed their behavior, and with their approach that they subordinate all their behavior to the patient. When caring for a mentally ill person it is necessary at least double the efforts to gain the trust for enhance the feeling of safety and security. Nurses are also aware that working with patients depends on his personal qualities and recognition of individuality.
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