National Repository of Grey Literature 36,160 records found  beginprevious36151 - 36160  jump to record: Search took 0.97 seconds. 

The role of radiology assistant during skeletal scintigraphy
Tejnorová, Kristýna ; Táborská, Kateřina (advisor) ; Vlček, Petr (referee)
Bone scintigraphy is an easy noninvasive method. The major function is to image changes of bone metabolism due to the uptake of radiopharmaceutical. Technetium -99m (99mTc) -labeled diphosphonates are the most widely used radiofarmaceuticals. The distribution of these tracers reflects blood flow and bone formation. Tracer that does not localize to bone is cleared by the kidney. Primary and secondary bone tumors, osteomyelitis and fractures are the most common indications for bone scintigraphy. Contraindication is pregnancy. Disadvantage of the bone scintigraphy is a low specificity of examination. The work explaines a working content of a technologist at the department of the nuclear medicine. Patient preparation and techniques are described. Skeletal scintigraphy may include radionuclide angiography and tissue phase at early phase, which is followed by skeletal phase imaging at late phase. This technique is called three phases scintigraphy. Standard bone scan is obtained 2-5 hours later after intravenous injection of radiotracer. A nuclear medicine specialist can decide after inspection the whole- body (WB) examination about addition single photon emission computed tomography (SPECT) or even SPECT/CT at newer scanners. These techniques provide a better anatomic localisation and may improve sensitivity and...

Using business process modeling tools for development of formalized medical guidelines
Mišúr, Juraj ; Richta, Karel (referee) ; Nagy, Miroslav (advisor)
This thesis is analyzing the usage of business process modeling (BPM) tools in the eld of medical guidelines. Business Process Management Notation is used for business process modeling and a sample medical guideline from the eld of cardiology is modeled with it. This guideline is then converted to Business Process Execution Language and executed in runtime environment to simulate the guideline behavior. Learned facts are then used to compare BPMN and BPEL with the existing modeling language for medical guidelines - GLIF. The practical result of this thesis is a prototype application evaluating medical guidelines modeled using BPMN and executed using BPEL. The guideline also communicates with electronic health record for gathering patient's data.

Homoeostasis of a Person from the Viewpoint of Cybernetics and Selected Simulated Themes in Education
Lapeš, Jakub ; Novák, Daniel (advisor) ; Vančata, Václav (referee)
Předmětem diplomové práce je kybernetický pohled na některé fyziologické děje probíhající v lidském organismu, které udržují stálost jeho vnitřního prostředí. Cílem je propojení biologické a kybernetické tématiky s možností uplatnění ve výuce na gymnáziích. Jsou zde probírány základy kybernetických metod a postupů, charakteristika živých soustav, vybrané fyziologické regulace lidského organismu, principy modelování a simulace biologických systémů, některé další mezipředmětové vztahy a vybrané didaktické aspekty řešené problematiky. Výsledkem pak je vytvoření názorného mezioborového vztahu (s příslušnou výukovou aplikací), mezi biologickými a technickými vědami, a návrh jeho možného začlenění do výuky na středních školách gymnaziálního typu. Jedním z východisek pro diplomovou práci jsou poznatky z vlastní pedagogické praxe.

Particle systems
Růžička, Martin ; Kmoch, Petr (referee) ; Pelikán, Josef (advisor)
The presented work deals with the issue of particles. It aims to offer a system for particle creation, simulation and visualization. The introductory part of the paper is devoted to design a physical model. The physical model particularly stresses a fast and at the same time plausible approximation of physical laws. Afterwards, it deals with methods of describing the particle behavior. In order to achieve the highest possible flexibility, a scripting interface is used. The conclusion then describes the visualization of the final particles itself. It is realized using the designed extension of the OpenGL graphic library. The results of the work can be seen in an enclosed application which demonstrates the possibilities of the designed particle systems.

Evapotranspiration impact on hydrological modeling
Macounová, Anna ; Kimlová, Martina (referee) ; Daňhelka, Jan (advisor)
This work presents the evapotranspiration from the point of view of its impact on hydrological modeling. We have tested the influence of different input evapotranspiration on the simualtion outputs of rainfall-runoff model Sacramento (SAC-SMA), which is the component of the hydrological forecasting system AquaLog used for flood forecasting in the Czech part of Elbe river basin. Litavka river basin was selected for this case study. We present physical geographical characteristics of the basin from the poin of view of influence of the evapotranspiration rate. Simulation using different computed evapotranspiration daily timeseries for 2001 - 2005 inputted SAC- SMA and total runoff, runoff composition, zones saturation were evaluated. Results proved that SAC- SMA sensitivity to evapotranspiration is of great concern especially for the long time and slow developing processes in the basin. Evapotranspiration loss, base flow generation and connected saturation of tension water zones and lower zone primary free water were identified to be the most affected states and processes. Powered by TCPDF (www.tcpdf.org)

The changes in gene expression and production of cyclooxygenases in the spinal cord due to pain and drugs
Procházková, Michaela ; Kršiak, Miloslav (advisor) ; Farghali, Hassan (referee) ; Rokyta, Richard (referee)
The aim of our study was to determine whether and how it changes expression and production of COX-1 and 2 in the spinal cord at different types of pain and to determine the effect of selected analgesics in the expression and production of COX-1 and COX-2 in the lumbar spinal cord in a model of inflammatory pain. All experiments were performed in the dissertation were performed in rats. Pain was measured using the plantar test and von Freys filaments. Expression of cyclooxygenase was tested using real-time PCR analysis, while the production of COX-1 and COX-2 was measured by ELISA method.

Valuation of the company PENAM, a.s.
Leharová, Olga ; Strouhal, Jiří (advisor) ; Smrčka, Luboš (referee)
Aim of this final thesis is assessment of the objectified value of the company PENAM, a.s. to the date of 1. 1. 2015. The valuation is performed from the perspective of an independent external subject, which means that only public sources are used. Theoretical and methodological part consists of enumeration and explanation of terms, methods and procedures connected with company valuation. Practical part represents application to praxis and includes financial and strategic analysis of the company PENAM, a.s., prognosis of value generators, financial plan till 2018 and the final valution. The discounted cash flows method is used as a main approach using the variant of free cash flows to the firm. There is also the book value and the value gained through V/EBITDA multiple for comparison.

The spread of moisture from sources of Mondi SCP and their impact on the microclimate after the project ECO PLUS - Installation of a new paper machine PM19
Sokol, Zbyněk ; Řezáčová, Daniela
The report summarizes the results of the assessment of the impact of changes in humidity and heat emissions from sources of Mondi SCP for selected climatic characteristics associated with the expansion of production at the new paper machine PS19A. The assessment is based on a comparison of impacts to the existing system resources, including an increase in pulp production (Project 2000), and extended system of resources associated with the operation of PS19A. The results were obtained by applying a mathematical model CT-PLUME/MONDI_R. The calculations were performed for the winter part of the years 2011 to 2014 and included an assessment of the impact of point and diffuse sources on the climatic characteristics of the model area.

Optimizing of air distribution in schools
Cigánková, Kristýna ; Šíma, Jiří (referee) ; Šikula, Ondřej (advisor)
The thesis deals with the issue of indoor air quality of schools and kindergartens. It focuses particularly on the inadequate ventilation and the application of forced ventila-tion in these types of buildings. The proposed solution is applied to a kindergarten in Kuřim. Measurements of the C02 concentration levels were performed in the presence and absence of air conditioning. To elaborate the proposed solution a simulation was made using a software called ANSYS Fluent. Input values for the simulation were obtained from an experimental measurement of a ventilation diffuser made by a company called Climecon ROX using the PIV method. This diffuser was then installed in the kindergarten. The measure-ments were carried out in the framework of the project the experimental validation of numerical models of the air flow in buildings marked with FAST-S-6-3387.

The Segregation in Ferrous Alloys when Casting Heavy Castings
Pernica, Vítězslav ; Čech, Jan (referee) ; Vodárek, Vlastimil (referee) ; Havlíček,, František (referee) ; Šenberger, Jaroslav (advisor)
This thesis is dedicated to the field of manufacture of heavy steel castings with resulting properties which are influenced by long solidification time. During the long solidification time a segregation process of additives in the steel occurs which results in numerous metallurgical defects. The work was intended to observe the macrosegregation effects in the wall of a heavy experimental steel casting respectively a part of a real superheavy casting intended for cement furnaces (weight 210 t). The steel casting for the research was manufactured in the joint-stock company of VHM where such heavy castings are commonly produced for the market. The supplied piece of the steel casting was cut into the smaller pieces for the better examination. The examination resulted in information about the casting macrostructure and chemical heterogeneity of chosen elements in the casting wall. The heterogeneity of the chosen elements (C, Mn, Si, Cr, S, P) is clearly shown in the worked out visual concentration maps. Based on the experimental data the measured results of segregations were confronted with the results of segregation modelling with the use of the commercial simulation software ProCAST. It resulted in the conclusion that the prediction of segregations is not in accordance with the reality. Furthermore, the results from the experimental casting are shortly compared with previously manufactured castings of the same type and the results summarizing the found range of macrosegregations of the tested sample are interpreted in the work conclusion.