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Optimization of Algae Population Growth Using Markov Chains and
Zouharová, Martina ; Kalčevová, Jana (advisor) ; Černý, Michal (referee)
The thesis deals with the task of refining the constructional and operational parameters of a tubular photobioreactor in order to maximise the growth rate of algae contained in the cultivation suspension. It builds on a basic growth model of the Porhydrium sp. alga, and focuses on the optimization of external irradiance, which is one of the key determinants of algae growth. Two distinct methodological approaches are applied: analytic approach, which employs Markov Chains, and simulation approach, which relies on agent-based simulations. In the analytic part, we introduce the construction of state transition matrix for a Markov Chain that accounts for varying irradiance inside the photobioreactor (in contrast to constant-irradiance methods that have been published so far). In the simulation part, we devised an agent-based model of algae population that enables us to analyze the system behaviour while interactively changing the model parameters. In the context of the results from both the analytic and simulation part, we conclude by suggesting the optimal level of external irradiance.
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Problems with the Phillips curve in developed economies
Krupička, Michal ; Babin, Jan (advisor) ; Slaný, Martin (referee)
My bachelor thesis focuses on the problems of the Phillips curve. Theoretical part is monitoring the development of the Phillips curve. In this part I describe the process of examination of this problem, that had begun a long time before introduction to work of A. W. Phillips. There are also mentioned works related to the Phillips work that were published after his paper and also some of the critics of the model. In practical part I constructed models to verify validity of the Phillips curve. Data of the Czech Republic and the United States of America were used in this part. Conclusion of practical part confirms that the validity of the Phillips curve is quite limited and that the practical use of the Phillips curve to influence the economy is not possible with this model.
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The study of interaction of platinum cytostatics with BCRP drug transporter using MTT cytotoxicity test
Horká, Markéta ; Čečková, Martina (advisor) ; Štaud, František (referee)
AAbbssttrraacctt The resistance of oncological diseases to cytostatic treatment is considered as one of the most serious problems of cancer treatment. One of the mechanisms by which cancers develop resistance is the overexpression of efflux transport proteins that limit intracellular concentrations of substrate agents. This work is focused on study of the interaction between clinically used platinum cytostatics (cisplatinum, carboplatinum and oxaliplatinum) and the efflux transport protein - BCRP. The experiments were made on MDKCII (parental cell line) and MDCKII-BCRP (cells were transfected by the gene of BCRP) cell lines. The results of the experiment with oxaliplatinum did not confirm any effect of BCRP on viability of BCRP transfected cells. Cisplatinum and carboplatinum tests provided evidence that BCRP transporter plays an important role in resistance development. The cells that were transfected by the gene of BCRP showed remarkably enhanced viability than parental MDCKII cells. However, the inhibition of BCRP transporter by specific inhibitor fumitremorgin C did not affect the viability of MDCK-BCRP cells. Such results suggest that the resistance of transfected cells was developed by other mechanism. Enhanced resistance could be caused by EGFP which is used as a reporting protein in preparation of...
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Family house with office part
Hradil, Michal ; Jelínek, Petr (referee) ; Rusinová, Marie (advisor)
Bachelor’s thesis „Family house with office part“ is made as building documentation under relevant laws and standards. The project processes a documentation of a new house construction. The house is designed as a two storey house with basement and flat roof. The house is located in the town Otrokovice in a build-up are of new construction houses. In basement are located technical premises, storage room and garage. In first floor is situated living room kitchen and idividually accessible office part. In second floor ale located bedrooms. The building is designed in a constuction systém Porotherm and based on concrete wall footings. The thesis is made as project for realization of building construction with studies and sources.
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Socio economic aspects chidren's understanding of politics on primary school
Pláničková, Veronika ; Dvořáková, Michaela (advisor) ; Kubišová, Zuzana (referee)
TITLE: Socio economic aspects children's understanding of politics on primary school ABSTRACT: This thesis focused on the research and subsequent diagnosis of students' conception of the political subject matter selected topics within the curriculum area Člověk a jeho svět at primary schools with regard to socio-economic situation in selected locations. In the theoretical part of thesis was based on several thematic units, which define the basic concepts and relations between them. Characterized the theory of constructivism, issues of curriculum students' concept, defined the educational area Člověk a jeho svět, said the terminology associated with preconceptions and described the methodology of educational research. In the practical part of the qualitative research - interview method, the results presented diagnostic approach to pupils' curriculum in selected locations. These results were compared with each other and analyzed together. In conclusion, the thesis gives recommendations for further research into this issue. KEYWORDS: Constructivism, Students'concept of curriculum, Children's interpretation of the world, Preconceptions, Socio economic aspect
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The influence of nursing documentation audit on nursing care quality
MACHÁČKOVÁ, Eva
Abstrakt The keeping of nursing documentation is an inseparable part of the work of a nurse. It is an instrument of professional practice, which is intended to support the process of care. The quality of the keeping of the nursing documentation is a reflection of the level of professional practice. The nursing documentation is an invaluable manner of supporting communication within the framework of the health care team and between the health workers and their patients/clients. Well kept nursing documentation is thus the product of good teamwork and at the same time an important instrument for increasing the quality of care. An audit is one of the parts of the management process and its final aim is to incease the quality of the provided care. An audit can play an important role during the delivery of the quality of the provided care and this is also true for the process of the keeping of the nursing documentation. During an audit of the kept documentation areas are identified where it is intended to ensure the improvement and education of the staff. The theoretical part the work also includes chapters related to the given problems that is the nursing aim, the nursing process, the nursing documentation, the quality of nursing care and the nursing audit. In the research part I deal with the influence of the audit of the nursing documentation on the quality of the provided nursing care. The aim of my research is to ascertain the influence of the standard of the nursing documentation on the quality of nursing care and to ascertain whether the results of the audit of the nursing documentation help the nurses in the wards to improve the quality of the provided nursing care. During the research my first hypothesis that the quality of the nursing care is increased by the carrying out of a standard ``Unified keeping of nursing documentation`` was confirmed and 26 of the questionned nurses (57%) agreed with it. The second hypothesis, that the quality of the nursing care is increased by the introduction of an audit of the nursing documentation into practice, was not confirmed. Only 18 of the interviewed nurses (39%) think that the introduced audit of the nursing documentation into practice is an increase in the quality of the nursing care. In order to obtain the required data to accomplish the aims and answer the hypothesis of quantitative research I used a method of auditing and an enquiry method using questionnaires. The research sample made up 50 (100%) of the examination documentation from five selected wards of Pelhřimov Hospital. The body of research in the case of the questionnaires was made by the nurses, working in the wards, where the audit of the nursing documentation was carried out. In total 46 of the nurses (100%) from all the assigned clinics took part in the survey. The results of the research were placed at the disposal of the administration of Pelhřimov Hospital, as a pilot study for the creation of their own complex standard and audit of the nursing documentation.
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Sex chromosomes in the house mouse hybrid zone
DUFKOVÁ, Petra
Understanding the genetic basis of reproductive isolation is the ultimate goal of the study of speciation. Here I present the results of a study of gene flow and its barriers at sex chromosome markers across the central European portion of the hybrid zone between two house mouse subspecies, Mus musculus musculus and M. m. domesticus. We identified strong introgression of Y musculus chromosome into the domesticus area accompanied by a perturbation of the census sex ratio. In addition, we detected stochastic effects that can distort results of hybrid zone studies. Finally, we confirmed a strong effect of sex chromosomes on reproductive isolation and hence their important role in the process of speciation.
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Analysis of tourism in selected region
Tomancová, Eva ; Svatošová, Libuše (advisor) ; Jaroslav, Jaroslav (referee)
This diploma thesis deals with the analysis of the evolution of tourism in the region Český ráj. Using time series methods there are analysed following indicators: traffic domestic and foreign visitors in collective tourist accommodation establishments, number of overnight visitors, the average number of overnight visitors, capacity of collective accommodation and attendance selected tourist objects Českého ráje. Individual indicators are constructed extrapolated prognosis future development for the years 2015 on the basis of exponential compensation in the program STATISTICA 10.
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Survey and evaluation of wooden construction
Křivánková, Soňa ; Anton, Ondřej (referee) ; Heřmánková, Věra (advisor)
This work is focused on compilation of general diagnostic methods used for diagnostic of wooden structures specifically listed wooden roof truss of church st. Bartholomew in Ivan. The main impulse of diagnosis was extensive damage and attack of truss and effort on rehabilitation and construction of the entire building of the church with an emphasis on preserving historical values. Diagnosis of truss was based on the research used sense and instrumental methods. In the first step, identify all dimensions of the individual elements of the structure was determined, the type truss system was intended. Follow-up survey was focused on determining the extent and causes of damage. In design of the rehabilitation process emphasis is placed on structural rehabilitation provided by follow-up processes, such as preventive chemical protection.
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Vnímání čínských hi-tech značek v Evropě
Vargasová, Nikola ; Král, Petr (advisor) ; Cook, Gina (referee)
The thesis "Perception of Chinese hi-tech brands in Europe" examines how Chinese origin affects the perception of hi-tech brands by European customers. The theoretical part deals with the concept of country of origin and its relationship to the concept of brand equity. The practical part is devoted to the research on the topic of perception of Chinese smartphones in Europe. The research results confirm both hypotheses: 1. Customers when choosing a smartphone brand are not affected by the country of origin. 2. European customers do not perceive Chinese hi-tech products as of low quality.
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