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OPTIMIZATION OF ALGORITHMS AND DATA STRUCTURES FOR REGULAR EXPRESSION MATCHING USING FPGA TECHNOLOGY
Kaštil, Jan ; Plíva, Zdeněk (referee) ; Vlček, Karel (referee) ; Kotásek, Zdeněk (advisor)
Disertační práce se zabývá rychlým vyhledáváním regulárních výrazů v síťovém provozu s použitím technologie FPGA. Vyhledávání regulárních výrazů v síťovém provozu je výpočetně náročnou operací využívanou převážně v oblasti síťové bezpečnosti a v oblasti monitorování provozu vysokorychlostních počítačových sítí. Současná řešení neumožňují dosáhnout požadovaných multigigabitových propustností při dodržení všech požadavků, které jsou na vyhledávací jednotky kladeny. Nejvyšších propustností dosahují implementace založené na využití inovativních hardwarových architektur implementovaných v FPGA případně v ASIC. Tato disertační práce popisuje nové architektury vyhledávací jednotky, které jsou vhodné pro implementaci jak v FPGA tak v ASIC. Základní myšlenkou navržených architektur je využití perfektní hashovací funkce pro implementaci přechodové tabulky konečného automatu. Dále byla navržena architektura, která umožňuje uživateli zanést malou pravděpodobnost chyby při vyhledávání a tím snížit paměťové nároky vyhledávací jednotky. Disertační práce analyzuje vliv pravděpodobnosti této chyby na celkovou spolehlivost systému a srovnává ji s řešením používaným v současnosti. V rámci disertační práce byla provedena měření vlastností regulárních výrazů používaných při analýze provozu moderních počítačových sítí. Z provedené analýzy vyplývá, že velká část regulárních výrazů je vhodná pro implementaci pomocí navržených architektur. Pro dosažení vysoké propustnosti vyhledávací jednotky práce navrhuje nový algoritmus transformace abecedy, který umožňuje, aby vyhledávací jednotka zpracovala více znaků v jednom kroku. Na rozdíl od současných metod, navržený algoritmus umožňuje konstrukci automatu zpracovávajícího libovolný počet symbolů v jednom taktu. Implementované architektury dosahují v porovnání se současnými metodami úspory paměti zlepšení až 200MB.

Methods for class prediction with high-dimensional gene expression data
Šilhavá, Jana ; Matula, Petr (referee) ; Železný, Filip (referee) ; Smrž, Pavel (advisor)
Dizertační práce se zabývá predikcí vysokodimenzionálních dat genových expresí. Množství dostupných genomických dat významně vzrostlo v průběhu posledního desetiletí. Kombinování dat genových expresí s dalšími daty nachází uplatnění v mnoha oblastech. Například v klinickém řízení rakoviny (clinical cancer management) může přispět k přesnějšímu určení prognózy nemocí. Hlavní část této dizertační práce je zaměřena na kombinování dat genových expresí a klinických dat. Používáme logistické regresní modely vytvořené prostřednictvím různých regularizačních technik. Generalizované lineární modely umožňují kombinování modelů s různou strukturou dat. V dizertační práci je ukázáno, že kombinování modelu dat genových expresí a klinických dat může vést ke zpřesnění výsledku predikce oproti vytvoření modelu pouze z dat genových expresí nebo klinických dat. Navrhované postupy přitom nejsou výpočetně náročné.  Testování je provedeno nejprve se simulovanými datovými sadami v různých nastaveních a následně s~reálnými srovnávacími daty. Také se zde zabýváme určením přídavné hodnoty microarray dat. Dizertační práce obsahuje porovnání příznaků vybraných pomocí klasifikátoru genových expresí na pěti různých sadách dat týkajících se rakoviny prsu. Navrhujeme také postup výběru příznaků, který kombinuje data genových expresí a znalosti z genových ontologií.

Optimization of network flow monitoring
Žádník, Martin ; Lhotka,, Ladislav (referee) ; Matoušek, Radomil (referee) ; Sekanina, Lukáš (advisor)
The thesis deals with optimization of network flow monitoring. Flow-based network traffic processing, that is, processing packets based on some state information associated to the flows which the packets belong to, is a key enabler for a variety of network services and applications. The number of simultaneous flows increases with the growing number of new services and applications. It has become a challenge to keep a state per each flow in a network device processing high speed traffic. A flow table, a structure with flow states, must be stored in a memory hierarchy. The memory closest to the processing is known as a flow cache. Flow cache management plays an important role in terms of its effective utilization, which affects the performance of the whole system. This thesis focuses on an automated design of cache replacement policy optimized to a deployment on particular networks. A genetic algorithm is proposed to automate this process. The genetic algorithm generates and evaluates evolved replacement policies by a simulation on obtained traffic traces. The proposed algorithm is evaluated by designing replacement policies for two variations of the cache management problem. The first variation is an evolution of the replacement policy with an overall low number of state evictions from the flow cache. The second variation represents an evolution of the replacement policy with a low number of evictions belonging to large flows only. Optimized replacement policies for both variations are found while experimenting with various encoding of the replacement policy and genetic operators. The newly evolved replacement policies achieve better results than other tested policies. The evolved replacement policy lowers the overall amount of evictions by ten percent in comparison with the best compared policy. The evolved replacement policy focusing on large flows lowers the amount of their evictions two times. Moreover, no eviction occurs for most of the large flows (over 90%). The evolved replacement policy offers better resilience against flooding the flow cache with large amount of short flows which are typical side effects of scanning or distributed denial of service activities. An extension of the replacement policy is also proposed. The extension complements the replacement policy with an additional information extracted from packet headers. The results show further decrease in the number of evictions when the extension is used.

Optical Measurement of Electromechanical Characteristics of Heart Cells
Čmiel, Vratislav ; Križanová,, Olga (referee) ; Babula, Petr (referee) ; Provazník, Ivo (advisor)
Dissertation is focused on the application of optical measurement methods using techniques of optical microscopy and fluorescence microscopy in measurements of electromechanical characteristics of isolated cardiac cells and clusters of differentiated cardiomyocytes. The first proposed method uses a practical combination of fluorescence microscopy equipped with fluorescent fast and high-resolution camera and atomic force microscopy for simultaneous measurement of calcium transients and contraction of cardiomyocyte clusters. The signals obtained undergoes filtration, processing and analysis. Result function parameters obtained by analyzing signals after application of caffeine are evaluated by comparison with functional parameters obtained during the control measurement. The second proposed method is applied to the cardiomyocyte clusters for the purpose of cardiomyocyte contraction signals measurement. The signals obtained by optical methods are analyzed and compared with the reference signal obtained using atomic force microscopy. Optical measurement method of cell contractins based on detection of cell ends using adjusting of microscopy images by re-sharpening and fluorescence method for cardiomyocyte contractions measurements were designed to increase realiability in simultaneous measurement of cell contractions simultaneously with calcium transients in isolated cardiomyocytes experiments.

The Pump with a Diffuser with Stochastic Blades (Runner and Diffuser)
Dobšáková, Lenka ; Melichar, Jan (referee) ; Veselý, Jindřich (referee) ; Haluza, Miloslav (advisor)
This doctoral thesis studies the non-uniform blade cascade for centrifugal pumps. Influence of non-uniform blade cascade is investigated on the impeller and diffuser. A non-uniform blading impeller of pumps in this doctoral thesis was examined in terms of influence on efficiency characteristic. The idea of using non-uniform blading is to obtain a flat efficiency characteristic. Then the centrifugal pump could be used on larger scale of power with achieving a sufficiently high efficiency. The work is based on experimental measurements and numerical simulations of non-uniform hydraulic pump components. Non-uniform impeller and the diffuser were newly designed for this research. A new measuring track of small submersible pumps was needed to design and build for measurements. Different pump combinations with conventional hydraulics on one working point and hydraulics with non-uniform were measured. All measurements were evaluated and characteristics of efficiency, head and power were obtained for each measured combination. Some of pump combinations (which were measured in experiment) were numerically simulated by program Ansys Fluent. Data needed to evaluate the characteristic of efficiency and specific energy were collected from each numerical simulation. A theoretical consideration concerns the influence of non-uniform blade cascade applied on diffuser. The suggestion how to decrease hydraulic losses in canals was done. The theoretical consideration how to make a flat efficiency characteristic was made.

Právní a zdravotně sociální aspekty činnosti OSPOD jako ustanovených opatrovníků v zámu nezletilých dětí
BORSKÁ, Jana
The Czech Republic as a signatory of the Convention on the Rights of the Child has vested the practice of state administration in the field of care for minor children to municipalities with extended powers, where the protection of the rights and legitimate interests of minor children is safeguarded by state authorities of social and legal protection of children (ASLPC hereinafter). These authorities are incorporated to the extent laid down by the Act on Social and Legal Protection of Children (Act No 359/1999 Coll., as amended). The position and roles of ASLPC and their competence and jurisdiction are also regulated by the same act. The position of workers of these authorities and its legal embodiment is equally important. Regarding professionality, there are high demands on these workers. In the Czech Republic, significant changes in legislature have been made over the past three years. These amendments have led to the strengthening of the rights of minor children and to the establishing of new tools for their protection. In connection with the adoption of new substantive regulation of family law, which is now exhaustively dealt with by the Act No 89/2012 Coll., the Civil Code, new procedural rules have been established regarding protection of rights of minor children. Such procedural legislation includes (apart from the long-existent Act No. 99/1963, the Code of Civil Procedure) the Act No 292/2013 Coll., on Special Civil Proceedings. The decision-making regarding minor children has been vested mainly by the state into the competence of courts. The courts appoint the locally relevant ASLPC as a guardian who then represents the interests of minor children. The purpose, interwoven with and derived from the first one, was to explore the opinions of selected social workers of ASLPC and of district court judges regarding the defined problems occurring during the work of ASLPCs and courts while protecting the interests of minor children. These particularly include: the use of the tool of precautionary measure; problems of different territorial jurisdiction of courts and ASLPCs; processing of complaints regarding bias in various phases of the proceedings; professional training of workers of ASLPC It is evident from the proposals of both judges and ASLPC workers that it is necessary to unify territorial jurisdiction. The courts are suggesting the priority criterion of the address where the child mainly resides. ASLPC workers suggest the official permanent residence as the prime criterion. Bias causes problems in all phases of proceedings. It is obvious that courts take differing approaches towards the solution of this problem (some courts solve the problem of bias complaints filed by the parties while other courts do not) and for ASLPC workers it is difficult to assess how to act when such complaint is raised against them. The training of ASLPC workers - workers are obliged to educate themselves and their employer is obliged to finance such training. Not all ASLPCs are able to provide training in the required extent - due to financial reasons (the average costs of education of one employee pose from 9,169 to 13,400 CZK annually and they cover approximately 6 days of training). The heavy work-load caused by insufficient numbers of ASLPC employees prevents them from completing such compulsory training. As part of the examination of the "participation of a collision guardian in court proceedings" it has been found out that irregular participation of the worker in the proceedings (absence from participation in appeals proceedings); incomplete reports (directed to courts) from surveys in families. Based on comprehensive examination of the problems of territorial jurisdiction, it was recommended that requests are independently recorded and financial compensation is provided for ASLPCs who are requested to represent minors in front of courts, to draft proposals for precautionary measures.

Adolescent overweight and obesity
JINDROVÁ, Kateřina
My bachelor´s thesis deal with obesity of adolescents and problems with overweight. These problems are described in details, and after that divided into specific parts. The main goal of my bachelor´s thesis is to chart problems with obesity and overweight in age group from 15 to 18 (adolescents) and primary describe their eating habits and physical activity. Theoretical part is focused on occurrence of overweight and obesity in the Czech Republic and in the world, causes of its origin, risk factors, classification and diagnosis, types, therapy and prevention. This bachelor´s work dealing with rational diet, describing basic principles of healthy catering and explaining right or wrong foodstuffs. I point mainly on prevention of overweight and obesity by healthy eating and physical activity. Methodical part is processed thanks to quantitative research. Data were gained by questionnaires, which were given to high school students (1st - 3rd grade). The research group contains 150 respondents from different schools in České Budějovice and close neighborhood. Final results are written down primary in graphs with commentary and data charts. In case of right use of qualitative research, there were determined two hypotheses. First hypothesis: Overweight and obesity is more occurred at adolescents with wrong eating habits. Second hypothesis: Overweight and obesity is more occurred at adolescents with low physical activity. For developing exploratory part, there was used quantitative research, which was provided by questionnaires given to students of age from 15 to 18. Entire data were processed by the use of program Microsoft Excel, and its calculations and functions. The answers of respondents were registered into database, and, by using specific excel functions, I was able to report data in determined categories. The research was mainly concentrated on physical activity and eating habits. Final results are put into well-arranged graphs, which are always enriched by comments, eventually completed by data tables, and, subsequently, statistically evaluated. In results, there might be seen two main differences between adolescents with standard weight and adolescents with overweight or obesity problems. One of those is irregularity in eating and wrong eating habits; big difference is also proved in physical activity. Adolescents with obesity or overweight have often irregular food intake, they drink a lot of high caloric beverages such as Coca-Cola, Sprite, Fanta etc., deficient income of fruit, vegetables, legumes, fish, or low physical activity. Only few of obese adolescents is different, because their problem is caused genetically. Adolescents with standard weight eat more regularly, but there are also some special cases, who have similarly wrong eating habits as obese people; however, all of these adolescents have one typical quality regular physical activity. Both hypotheses are confirmed. The results show that obesity is mainly caused by genetic predispositions, but these factors can be positively affected by periodic physical activity or appropriate eating habits. At the end of the thesis, it should be mentioned that it is necessary to be focused on right eating habits and regular physical from the very young age, when the basic customs and habits are assumed. That should include parents' action around their children, as they are usually the first example and they have the biggest influence.It is important to develop knowledge about all kinds of prevention, which are in most cases major in defending against formation of overweight and obesity.

Characteristics of the working behavior of Czechs and Ukrainians
BYKOVA, Sofia
The aim of this work is to create a transparent and comparable characteristics of the work behavior phenomenon within the cultures of those states - what is common and what is different between them, or maybe incompatible .It is supposed to have some analysis of possible conflicts and their connection with the mentality. The primary reason of this aim choosing is the specialty I study. My work contains information that could be interesting and useful not only for me and my future job, but also for managers and other employees. Overview of examined issues contains specific points, such as the fundamentals of economic psychology and behavioral economics (symbiosis of psychological and economic opinion on motivation and rationality of individuals), theories of motivation and reaction to different occurrence, characteristic of the term "mentality", general points about the human impact of the world economy. For realizing the goals of my work the following hypotheses have been proposed - Czech and Ukrainian mentality have significant differences, though these cultures are close. - Ukrainian and Czech employees are able to work effectively in a team and find a "common language" in the workplace. The difference in mentality does not obstruct on it. - Employers could be interested in the Ukrainian employees taking into account their high concernment and motivation. All three of the hypotheses were confirmed by observed data and comparison of mentality characteristics. Czechs are often tolerant to other cultures, moreover Ukrainian culture is not much different and does not create difficulties in the working relationship. Based on the fact that the chosen company has no conflicts associated with work behavior and differences in mentality, it's hard to define my contribution to this organization work.

Matematická analýza regularizovaného modelu viskoelastické nenewtonovské tekutiny
Šalom, Pavel ; Pokorný, Milan (advisor) ; Bulíček, Miroslav (referee)
In this thesis we provide an existence result for a regularized model of viscoelastic non- newtonian fluid. We consider incompressible fluid with shear rate dependent viscosity and with Cauchy stress tensor capable to describe stress relaxation. An elastic part of the Cauchy stress tensor is governed by Oldroyd-type differential equation. In particular, we are interested in fluids with strong shear thinning effect. We prove that if the viscosity function µ (D) is such that tensor µ (D) D is p-coercive, monotone and has (p − 1)-growth for p > 6 5 and some other additional assumptions are satisfied, then there exists a solution to the system of PDEs describing the flow in a bounded domain. The proof is not simple because the convective term is not integrable with a high power. The problem is solved using Lipschitz truncation method for evolution PDEs. 1

The Specifics of the nursing care in catering for long- term dialysis patients
ŠRÁMEK, Kamil
Haemodialysis is a method of removing waste substances such as potassium, urea and excess water from the blood during renal failure. Hemodialysis is one of three renal replacement therapies. Other treatments are a kidney transplant and peritoneal dialysis. Hemodialysis can be performed either in the hemodialysis center, or in a hospital, but home hemodialysis is not too frequent. Eating for dialysis patients differs significantly from the forward dialysis diet period. A well balanced diet is the foundation of everything. The patient may neither be malnourished, nor to have surplus of any components in their diet. A diet for patients in dialysis program must meet two basic requirements; the diet must provide enough energy and substances needed by the body mainly amino acids required for the production of protein, calcium, vitamins, iron, restrict certain substances that accumulate in the body is harmful, for example, fluid restriction, excess protein from which the formation of urea, excess phosphorus, which accelerated calcification of blood vessels, excess potassium, which at high levels in the blood can cause heart rhythm disturbances. Qualitative research was carried out by interview. The interview contained a total of twenty semi-structured questions and was prepared in advance. Each interview was anonymous and each respondent had the opportunity to refuse it. With the consent of the respondent and the ward nurse, the interview was recorded on a tape recorder and later adapted into an electronic form, which became the basis for the research. From the research arose categories. Qualitative research file conducted in hospitals Prachatice, České Budějovice and Třebíč. The research sample consisted of five respondents in the Nemocnice Prachatice a. s. Another research sample consisted of five respondents in Nemocnice Třebíč and two respondents in the Nemocnice České Budějovice a. s. All respondents were patients who regularly attend to hemodialysis centers in these cities. Interviews with respondents were conducted from February to April 2014. In the Nemocnice České Budějovice a. s. the research survey was conducted with the consent of the Deputy for nursing care, Mgr. Kyselová. In Nemocnice Prachatice a. s. the research survey was conducted with the consent of the head nurse in the hospital Janoušková and in the Nemocnice Třebíč the research was conducted with the consent of the Deputy for nursing care Mgr. Andělová. The results of the survey provide mapping meals in the hospital for long-term dialysis patients. The benefits of the research will be to develop an information leaflet on the topic: The importance of catering for dialysis patients.