Národní úložiště šedé literatury Nalezeno 122 záznamů.  začátekpředchozí31 - 40dalšíkonec  přejít na záznam: Hledání trvalo 0.04 vteřin. 
Nové prostředky k indukci ovulace u ryb
Barth, Tomislav ; Barthová, J. ; Hamáčková, J. ; Kouřil, J.
Je uveden přehled nově nalezených peptidů podobných jak primární strukturou tak účinkem savčímu GnRH. Jsou presentovány vývojové přípravky obsahující jak synthetické analogy různých GnRH tak některé dopaminergní inhibitory, které nalezly uplatnění v komposici kombinovaných preparátů pro umělý výtěr ryb. (Dagin, Ovopel, Aquaspawn).
Synthesis and cytostatic activity of 2,6-diamino-9-benzyl-9-deazapurine and related compounds
Otmar, Miroslav ; Masojídková, Milena ; Votruba, Ivan ; Holý, Antonín
2,6-Diamino-9-benzyl-9-deazapurine and 9-benzyl-2,6-bis(benzylamino)-9-deazapurine were synthesized by reductive cyclization of the corresponding 6-cyanomethyl-5-nitropyrimidines. Both compounds exhibit cytostatic activity in human T-lymphoblastoid CCRF-CEM cells.
Covalently linked purine dimers or trimers and purine-pyrimidine conjugates - analogues of nucleobase-pairs or triplets
Hocek, Michal ; Dvořák, D. ; Havelková, M.
Covalent analogues of pairs and triplets of nucleobases consisting of purine dimers and trimers and purine-pyrimidine conjugates connected by various types of carbon-linkers (acetylene, diacetylene, vinylene, ethylene, phenylene, benzenetriyl) are described.
Synthetic approaches to "opened-ring" acyclic nucleoside phosphonates - novel type of antivirals
Holý, Antonín
Diverse synthetic approaches to "opened-ring" acyclic nucleoside phosphonates - novel type of antivirals are described.
From nucleoside phosphonic acids to modified oligonucleotides
Rosenberg, Ivan ; Endová, Magdalena ; Králíková, Šárka ; Liboska, Radek ; Rejman, Dominik ; Točík, Zdeněk
A number of new isopolar phosphonate nucleotide analogues were prepared and a large set of oligonucleotides containing structurally diverse modification internucleotide linkages could be created.
Isosteric phosphonate mono-and oligonucleotides originating from 4',5'-didehydronucleoside precursors: some synthetic possibilities and limitations
Točík, Zdeněk ; Liboska, Radek ; Barvík, I. ; Buděšínský, Miloš ; Masojídková, Milena ; Kavenová, Ivana ; Rosenberg, Ivan
The work deals with aspects of synthesis and properties of isosteric phosphonate analogs of 5'-monophosphates and with structure-properties relationship of the related oligothymidylates.
Chemistry of Nucleic Acid Components. 12th Symposium
Točík, Zdeněk ; Hocek, Michal
In keeping with the main goals of the well-established series, the main topics of the XII NAC symposium covered the synthesis, transformations, physical chemistry, and biological activity of nucleosides, nucleotides and oligonucleotides as well as the aspects of their molecular biology in the broader sense.
12th International Biodeterioration and Biodegradation Symposium
Macek, Tomáš ; Macková, M. ; Jenč, P. ; Demnerová, K.
The schedule of symposium is quite rich and includes sessions on a broad variety of related topics, ranging from biochemistry and genetics of biodegradation of organic compounds, issues of environmental toxicity, through construction of genetically modified organisms, to the biodegradation of cultural property.
Vibrational circular dichroism of peptides in the region of N-H and C-H stretching vibrations
Maloň, Petr ; Gut, Vladimír ; Pospíšek, Jan ; Vašíčková, Soňa ; Coufalová, Pavla ; Mařík, Jan
A new vibrational circular dichroism spectrometer, which is optimized for the near IR region is developed. The instrument is based on the classical concept using a monochromator.

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