|
Analysis of Exchange Rate Regimes under Conditions of Economic Transition
Stejskal, Jan ; Taušer, Josef (advisor) ; Plchová, Božena (referee)
This paper concentrates on the analysis of currency crises in economies undergoing economic transition. The papaer begins with a brief introduction of contemporary exchnage rate regimes, which is followed by an analysis of the history of the World monetary system. The following chapters concentrate on the analysis of the monetary development in selected transitional economies. In case of the the first one, The Czech Republic, the analysis includes the period from the times of the centrally planed economy, through the initial transformation and the currency crisis of 1997 to the present day. In case of the other countries included in this paper, Latvia, Estonia, Lithuania and Icelnad, the analysis concentrates on the current critical development in these economies. Apart from the analysis of the selected currency crises, the objective of this paper is to draw conclusions relevant to the future development of currency policies in the transitional economies.
|
|
Effect of flavonoids on the metabolism of xenobiotics
Smetanová, Anna ; Szotáková, Barbora (advisor) ; Boušová, Iva (referee)
Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Biochemical Sciences Title, Name, Surname of candidate: Mgr. Anna Smetanová Title, Name, Surname of tutor: Doc. Ing. Barbora Szotáková, Ph.D. Title of a rigorous work: The influence of flavonoids on the metabolism of xenobiotics Flavonoids are wide spread plant secondary metabolites with the protective effect against the cancer. One of the protective mechanisms of action is the modulation of the biotransformation enzymes. Xenobiotics - heterocyclic aromatic amines are presumably carcinogenic compounds generated during the ordinary cooking of meat and fish. The first metabolic step of the heterocyclic aromatic amines is the procarcinogen activation to the active N-hydroxy metabolites by cytochrome P4501A2 (CYP1A2). It would be desirable if the flavonoids in the appropriate manner modulate the enzymatic activity to eliminate the undesirable effects of the heterocyclic aromatic amines. The aim of this study was to investigate the influence of the rutin and quercetin flavonoids and heterocyclic aromatic amines 2-amino-3-methylimidazo[4,5- f]quinoline (IQ) and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) on CYP1A activity in the cell line LS174T and HCT-8. Rutin, quercetin, IQ and MeIQx were not toxic for cells up...
|
|
.
Šejda, Tomáš ; Poledne, Rudolf (advisor) ; Filipovský, Jan (referee) ; Češka, Richard (referee)
Based on the results of our study, we concluded that the degree of brachial artery flow endothelium-dependent dilatation is difficult to evaluate using predefined cut-off points as a single-measurement screening test to indicate endothelial dysfunction. On the contrary, the variation of endothelial function after a defined stimulus (dietary, medication) examined at a predefined interval using an identical protocol can help to assess enhanced or reduced efficacy of endothelium-dependent vasodilatation. In the next study, we demonstrated that a high-fat load applied at a single dose does not significantly affect brachial artery vasoreactivity in young, healthy volunteers after four weeks of low- and high-fat diets. In contrast with atherosclerosis, the effect of hypercholestrolemia on adhesive molecule levels has been a source of controversy. We demonstrated that 3-month therapy with fluvastatin does not decrease cICAM-1 levels despite normalization of cholesterol levels. The implication is cholesterol may not induce endothelial activation by the initial upregulation of this adhesive molecule. Endothelial dysfunction can be considered the initial, functionally relevant stage of atherosclerosis, demonstrable still before morphological changes. In patients with advanced obliterative atherosclerosis,...
|
|
Change of lung perfusion in time after pulmonary embolism
Lvončík, Martin ; Lang, Otto (advisor)
Pulmonary embolism is a serious disease whose diagnosis and therapy is very consuming and must be urgent . Pulmonary embolism occurs closing the pulmonary artery or their branches thrombus which may be generated in situ, rarely , but more frequently occurs in some distant location of the vascular system . This state may be called as thromboembolic disease. Despite ever -improving diagnostic capabilities remain a number of cases of pulmonary embolism undetected . The first and most important step in the diagnostic algorithm for pulmonary embolism even think based on the clinical picture of the patient. The actual pulmonary embolism can occur with different variability and therefore it is necessary to correct after diagnosis without delay appropriate medical treatment . I correctly indicated treatment may have number of side effects , so the therapeutic regimens on the basis of new clinical studies are still being upgraded. Lege Artis procedures are designed in our country and described recommendations in the diagnosis and treatment of pulmonary embolism Czech Society of Cardiology . The last revision was in 2007. The aim of optimizing therapy is to reduce the number of relapses , side effects and complications , prevent fatal consequences of pulmonary embolism , extension of life, quality of life , reduced...
|
|
Customer relationship management in outsourcing of IT
Horáček, Jan ; Bruckner, Tomáš (advisor) ; Vaněček, Michal (referee)
Outsourcing of IT is likely to be a perspective model of IT service delivery. However, only a small number of companies have adopted it and according to surveys, their satisfaction is relatively low. On the contrary, customer relation management (CRM) is a marketing approach that still keeps its popularity. Is not therefore CRM a solution also for outsourcing of IT? How should it be applied in the field? This master's thesis is intended for providers of outsourcing of IT and it aims to find answers to the questions above. The first step towards the goal is to identify main characteristic features of outsourcing of IT, which consequently provide a guideline for a systematic approach to the solution. The thesis does not presume reader's familiarity with CRM, hence the second chapter offers a brief yet holistic view of the issue. A synthesis of the information from the first two parts leads to a conclusion that it is not possible to decide about suitability of CRM in outsourcing of IT on a general basis, but always in the particular situation. Therefore the work suggests a set of criteria for the choice. The consecutive chapters deal with the application of CRM. Firstly, an entire system of tools for evaluation of customers is proposed. It enables providers to determine the suitable level of individual approach to each customer with consideration of both business and technical factors. Consequently, a provider can start building a relationship with his customer taking advantage of number of recommendations and tools given by this paper. It includes measures not only for convincing customers but also for increasing their retention. The thesis discusses broad variety of aspects of marketing in outsourcing of IT. Its scope ranges from customer uncertainty mitigation and purchasing process of a corporate customer, over tips on how to manage customer satisfaction, to appropriate adjustments of a service level agreement (SLA). The paper also briefly analyses the specifics of CRM in outsourcing of IT in the public sector.
|
|
Ecotoxicological evaluation of contaminated water and soil and use of biotests for bioremediation
Hubálek, Tomáš ; Novotný, Čeněk (advisor) ; Pazlarová, Jarmila (referee) ; Malachová, Kateřina (referee)
2 2. Abstract The aim of this thesis is to identify the ecotoxicity of contaminated soil and water during bioremediation. Different test organisms were selected for the battery of ecotoxicity tests such as the bacterium Vibrio fischeri, the terrestrial plants Sinapis alba, Lactuca sativa, and Hordeum vulgare, the water plant Lemna minor, the earthworm Eisenia fetida, and the crustaceans Daphnia magna and Heterocypris incongruens. A comparison of individual biotests with various organisms and endpoints should demonstrate their suitability and sensitivity for the ecotoxicity evaluation of contaminated soil and water. The bioassays were used for the evaluation of the bioremediation of hydrocarbon-contaminated soil, composting of PAH-contaminated soil and remediation of contaminated groundwater. The ecotoxicity of hydrocarbon-contaminated soil originating from a brownfield was evaluated during a 17-month biodegradation pilot test (experiment I). The initial concentration of total petroleum hydrocarbons (TPH) in the soil was 6380 μg.g-1 dry weight; the concentration of TPH in the soil decreased by 65.5 % after bioremediation. The highest toxicity was detected in the first period of bioremediation; however, certain toxic effects were detectable during the whole bioremediation process. The contact tests were the...
|
|
Use of DMS for paperless office
Strnad, Marek ; Kunstová, Renáta (advisor) ; Bachmann, Petr (referee)
The theme of this bachelor thesis is the use of DMS for paperless office. In the first part the author deals with what must be taken into account when realization a paperless office. What are the legal aspects associated with operating a paperless office in the Czech Republic and what facility is needed to do. When author writing this bachelor thesis, he has worked with AiP Safe s.r.o., which gave him the analysis of projects. From these analysis is then processed the second part, where is described which agenda is the most often deployed by system SAFE. Then author describes what the initial situation was and what benefits from the use of paperless office for various companies meant. Conclusion of the thesis is devoted to evaluation, if appropriate deployment of DMS increases speed and efficiency of processes and activities, whether there is compliance with legislation and internal rules.
|
|
Business plan of development of a new spa resort
Eisenreich, Jindřich ; Kvítková, Zuzana (advisor) ; Mlejnková, Lena (referee)
The purpose of this dissertation is a formulation and analysis of a business plan for development of a new spa resort in Františkových Lázních and conduct feasibility study of proposed business case. The following work is divided into theoretical and practical part. While theoretical section of the dissertation outlines main terms and theoretical concepts, explains relevant legal and regulatory conditions and restrictions relating to offering spa services and details all factors necessary for appropriate formulation of presented business case. Practical part of the dissertation presents a real life business case together with a feasibility study of the proposal, competitor analysis, market research and planned marketing strategy, while analysing returns of invested capital in three alternative scenarios.
|
|
Economic Research Bulletin (2015, No.1). Volume 13, Number 1, May 2015, Forecasting
Česká národní banka
Appropriate, state - of - the - art forecasting techniques are crucial for guiding the monetary policy decisions of central banks. At the same time, knowledge of the initial conditions in the economy is a prerequisite for good forecasts. Such knowledge is incorporated as expert judgement on top of the model forecast. It is also important to understand which factors contribute to differences between two (old and new ) forecasts. This edition of the Research Bulletin presents four articles that describe recently developed forecasting techniques, the role of expert judgement in the forecasting process, and a new structural model forecast evaluation technique used at the Czech National Bank.
Fulltext:  PDF
|
|
Analysis and processing of measured data from crash tests
Klein, Martin ; Coufal, Tomáš (referee) ; Tokař, Stanislav (advisor)
This thesis presents four crash test of two cars, in which always a moving vehicle strikes with fully overlaid front part into the side part (cabin for passengers) of another stationary vehicle. Crash test were carried out to detect the impact parameters for use in the road accidents analysis. Experimentally measured data and the acquisition of documentation during crash tests were therefore analyzed in an appropriate manner in order to obtain relevant impact parameters. One of the main evaluated parameters was the deformation energy that has been used for the permanent damage to vehicles. In the forensic engineering practice for analyzing vehicle impacts is as a control parameter used EES (Energy Equivalent Speed), this parameter was counted according to measured values during crash tests.
|
guest ::
