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Development and optimization of sample preparation step for fast chromatographic analysis
Pilařová, Veronika ; Nováková, Lucie (advisor) ; Bednář, Petr (referee) ; Šatínský, Dalibor (referee)
Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of analytical chemistry Candidate Mgr. Veronika Pilařová Supervisor Assoc. Prof. Lucie Nováková, Ph.D. Title of Doctoral Thesis Development and optimization of sample preparation step for fast chromatographic analysis. The aim of the dissertation thesis is the development of modern extraction methods for the sample purification and for the analytes isolation and preconcentration from various biological materials, including biological fluids (plasma, serum, vaginal lavages) and plant material. Modern approaches have a lots of advantages such as a lower consumption of sample and organic solvents, extraction speed-up, better sample purification, matrix removal and lower influence of matrix effects. Extracts from modern microextraction methods can be analyzed by separation methods including ultra-high performance liquid chromatography and supercritical flluid chromatography coupled with mass spectrometry. The separation methods enable fast high-throughput analysis with sensitive and selective detection. Individual projects show the possibilty of use of the modern approaches in the sample preparation field, where the microextraction by packed sorbent (MEPS), microextraction by solid phase extraction in pipette tips...
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Quality of life of patiens with chronic obstructive pulmonary disease
Musilová, Lada ; Janíková, Taťána (advisor) ; Vašáková, Martina (referee)
The aim of this dissertation is to describe in what way the quality of life of clients suffering from chronic pulmonary disease is influenced and which spheres of their lives are afflicted most frequently. The research part is aimed at the most troublesome and limiting spheres which make the lives of these people unpleasant or which even make some daily routines, occupational activities, leisure time activities, social life, etc. impossible. The research has been carried out in the form of the semistructured dialogue and with the assistance of SEIQoL methodology. It targets at the clients being in their working age.
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Values and motivation of criminal-law barriesters
Hurychová, Zuzana ; Morgensternová, Monika (referee) ; Slaměník, Ivan (advisor)
This dissertation deals with values and motivation of barriesters active in the sphere of criminal law. The work itself concentrates above all on such values that have much broader functions in the personality of man than mere motivation. The dissertation shows in the theoretical part the theme of values from the point of view of various theories and also the relations between the values and personalities or their other motivational components. Simultaneously value research methods are introduced here as well as their usage in practice. The goal of the empirical part is to show specifics of value orientations of barriesters, men and women, active in the sphere of criminal law which considerably differ from the characteristics of ordinary population or which strongly differ depending on gender. A group of barriesters (regardless of gender) shows in comparison with ordinary population distinctive preference of the social values type and the overall value profile differs to a high extent in the questionnaire Study of values from the ordinary population especially the profile of female barriesters. Some characteristics of value profiles in the questionnaire Study of values discovered similarity of female barriesters with ordinary male population and of male barriesters with ordinary female population. In the...
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The development of employment policy in the CR since 1990
Trávníček, Vojtěch ; Peřina, Pavel (advisor) ; Kotous, Jan (referee)
65 IX. RESUMÉ 9.1 Sales Agreement on the Enterprise This dissertation concerns the enterprise as the object of commercial law relationships. It is divided in five thematic parts /blocks (see Section 2-6). In the first part I am dealing with a legal definition of the enterprise pursuant to the Czech Commercial Code. The definition of enterprise included in the Commercial Code is construed quite broadly in order to cover all elements of the enterprise. The basis for the definition of the enterprise is a decision concerning application of Montan Union Treaty Manessman dated 13 July 1962. No obligations belong to the definition of the enterprise. Qualification of the enterprise as a collective thing causes some difficulties, because the conception of the enterprise as a collective thing is in the Czech system of law neither defined nor legally regulated. Finally, I mentioned shortly a conception of the enterprise in the European law. According to the current legal regulation, the enterprise is understood as an object of legal relationships. I consider for substantial classification of dispositions with the enterprise on contractual and noncontractual. The second part of my dissertation covers all possible contractual dispositions with the enterprise. The other parts of the dissertation cover the most important...
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Adoption - a comparison between the law of the Czech Republic and Germany
Péková, Kateřina ; Frintová, Dita (advisor) ; Pohl, Tomáš (referee)
76 Abstract (anglické resumé) Adoption - comparing of the legal regulation in the Czech Republic with the Federal Republic of Germany The dissertation compares adoption problems in the Czech Republic and in the Federal Republic of Germany. The First Chapter considers the historical development of adoptions in both countries comparing legal regulations. Principle of the full adoption is described in the first part of Chapter Two. The second part shortly explains the difference between revocable and non-revocable adoption, which is possible in the Czech Republic. Chapter Three is the most extensive one. This chapter focuses on the adoption of minors. First it analyses and compares the terms of adoption. For easier orientation the terms are subdivided into four groups: the first looks at the terms on the side of adoptive parents, the second group deals with the terms on the side of adoptive child, the third shows terms on the side of biological parents and the fourth group deals with further terms of adoption. Each group describes terms according to the Czech and German law separately and then compares them. Besides the terms of adoption Chapter Three deals with the adoption process. It contains mediation process, proceedings for determination whether biological parents' consent is necessary, which Czech law...
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The sales contract and its consumer aspects
Málek, Radek ; Pohl, Tomáš (advisor) ; Macková, Alena (referee)
76 Résumé Purchase Contract and its Consumer Aspects This diploma thesis is concerned with the purchase contract and its consumer aspects. After the introductory, in the second chapter, the thesis defines generally the purchase contract as one of the most important contracts in the Czech legal system at all, including its roots reaching to the Roman law. In the third chapter, the thesis describes the consumer protection in the Czech legal system, which is traditionally divided into two sections - the consumer protection provided by the public law and the consumer protection provided by the private law. Both, the public law and the private law interfere reciprocally to each other and so they build the complex of the consumer protection in the whole legal system in the Czech Republic. In the forth chapter, this dissertation distinguishes between the application of the legal regulation in the Czech Civil Code and the Czech Commercial Code and it depicts the rules of application of both these Acts. Further, this chapter thoroughly analyses the unambiguous term of consumer. The term of consumer is in the Czech legal system defined on many places in various codes and so the interpretation implies troubles with understanding. Next to these problems of interpretation, there is a consumer law of the European Union...
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Advantages and disadvantages of each legal forms of entrepreneurship
Jandová, Iveta ; Kalinová, Miluše (advisor) ; Žák, Květoslav (referee)
The purpose of this dissertation is to reveal advantages and disadvantages of the national forms of entrepreneurship according to the valid legal regulations in the Czech Republic. All facts are supported by practical skills and in conclusion all practical and theoretical information is summarised. The goal of this thesis is to simplify and to structure the issue in a well-arranged way and to draw a conclusion based on both practical and theoretical knowing.
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The Influence of the Human on Nature in a Historical Context with an Educational Hike - Týnec nad Sázavou
Macháčková, Lenka ; Přívratský, Vladimír (advisor) ; Ziegler, Václav (referee)
The principal goal of this diploma thesis is to study the impact of human's activity on the nature in the region of Týnec nad Sázavou from the beginning of the human's colonization until today. This impact was not only negative, we can find positive influences, too. The work is divided into six general chapters that describe always one particular problem. Purposes and hypothesis of the diploma thesis are introduced in the first chapter, which is a prologue of the present work. History of Týnec nad Sázavou and of the country around is described in the second chapter and provides an image of the city's industrial and structural development. Research work of the influence of human's activity on the nature during the history is presented in the third chapter. Several domains were studied: geology, relief and country sight, climatic effects, soil, fauna and flora in Týnec and surroundings, nature protection, forests, river Sázava, housing, industry, traffic and other networks. Situation in the history, present condition of the nature, author's evaluation and suggestion for regeneration are described for every field of study. Chapter four introduces theory of didactical walk and his benefits for children education. Chapter five details some suggestions of educative walks in the region of Týnec nad Sázavou. Each...
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Pressure of advertisiment on consumer behavior of pharmacy visitors
Štěpánová, Vendula ; Fabera, Vladimír (advisor) ; Kotlářová, Jana (referee)
1 SUMMARY INFLUENCE OF PROMOTION ON CONSUMER BEHAVIOUR OF VISITORS OF CHEMIST'S Author: Vendula Štěpánová Tutor: PhDr.Vladimír Fabera, CSc. Dept. of Social and Clinical Pharmacy, Fakulty of Pharmacy in Hradec Králové, Charles University in Prague, Czech Republic Aim of study: The objective of this work is to observe an influence of people by a promotion of drugs. An observational part was made according to a survey, where 14 questions were asked. Methods: I have taken up the dissertation of Krkošová 2000 and Pacasová 2002. I have chosen some questions which are the same as the questions in the dissertation of Krkošová and Pacasová. The reason was to compare results from both works with my results. Other questions were different. The questions were asked so everyone could understand and answer them. Respondents had to choose and highlight or could write their own answers. Then the answers were analysed. Results: 160 people participated in this research. 80% of the respondents have answered that they were not ifluenced by promotion during 6 months. Respondents who were influenced by promotion got the information from TV. 39% of the respondents do not prefer drugs seen in advertisements. 52% of the respondents have answered that they were interested in new drugs, but it only depends on what kind of drug it is....
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