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Support for Romany Secondary School Students
BŘEČKOVÁ, Gabriela
The theoretical part of this thesis is dealing with the differences in education in Romany families as compared to majority families, the education of the Romany minority, educational opportunities of Romany students and inequalities in the transition to high schools as compared with the majority population. Additionally, it describes the reasons for early drop out of Romany students from secondary schools and the concept of the Support is defined, as well as its changes that had taken place over the years till June 2011. The objective of this thesis is to identify the effectiveness of the Support of socially disadvantaged Romany secondary school students and college students. To obtain the necessary data, the method of qualitative research was chosen, the technique of semi-structured interview supplemented by secondary data analysis. The research group consisted of eight representatives of secondary schools in the South Bohemian Region County who asked for the Support in the past. The research results show that all Romany students apply for the Support at the outset of their studies, most of them repeatedly and separately for each period. If a Romany student meets the conditions for granting the Support, he/she must meet the conditions for the payment of the Support. The subsidy granted is paid retroactively in December, for the period from September to December, and in June, for the period from January to June. The unused finance is returned to the Ministry of Education. At the same time, the research suggests that completing the application form for the Support is not easy. The number of Romany students who applied for the Support from January 2005 to June 2011 shows a downward trend. The reasons for not using the Support included, in more than half of Romany children, an incorrect estimate of education costs and also a failure to submit the relevant documents for the retroactive payments; in 21 % of the cases the Support was not used due to drop out of the student, and the rest was due to unexcused absence. It is expected that this thesis could serve as an information source for the general public because the Support, also called positive discrimination, is a powerful motivational tool for socially disadvantaged Romany students for whom it is not easy to continue with their secondary education. At the same time, this thesis could become a source of research for other regions too.

Molecular simulations in structure analysis of intercalates
Veteška, Marek ; Pospíšil, Miroslav (advisor) ; Beneš, Ludvík (referee)
The samples of hydrotalcite intercalated with pyrenetetrasulphonate acid were obtained. Their structure cannot be precisely determined by the analysis of X-ray data. The amount of water in the interlayer space and the structure of the samples differed considerably in dependence on humidity. Convenient procedures and minimization strategy were established on the base of X-ray data in the molecular mechanic and the molecular dynamic simulations. A procedure for using of the supramol software was made. This software enables deterministic searching of conformational space. Initial models from supramol were minimized in the Cerius2 software using the Universal force field and then they were eventually optimized by the molecular dynamics. The arrangement of molecules of pyrenetetrasulphonate acid and water was determined in the interlayer space of hydrotalcite for three different samples with different interlayer distances: The sample 1 prepared by RH = 0%: 9.83A; the sample 2 prepared by RH = 84%: 13.63A; the sample 3 prepared RH = 40%-50%: 11.74A a 12.81A. The results of these structures proved a large variability of the arrangement of the molecules in the interlayer space. The sample No. 3 seems to be unstable.

The Use of Physical Education Equipment in P.E. Instruction at Primary Schools
Kodejšková, Petra ; Hronzová, Marie (advisor) ; Zachariášová, Jana (referee)
In my diploma thesis I solve the present situation of applying new development's trends in the area of Health Physical Education of primary school aged children. In the theoretical part, I try to show the characteristics of Health Physical Education from different points of view, e.g. historical, type of weakening, determination of tasks and aims, considering of exercise units and correct principles of Health Physical Education. The main focus of the theoretical part of my diploma thesis is the characteristics of physical education's tools. I try to bring near the information about the usage of traditional and non-traditional tools in Health Physical Education from systematic and complex point of view. The research of my diploma thesis comes out of the theoretical principles and concerns on usage of physical education's tools at primary schools. I try to explain the present situation of this problem through several research methods (questionnaire, conversation, observation and experiment in term of Health Physical Education's unit). The results of my research bring a lot of information, which discovers the absence of exercises with some tools in Physical Education at primary schools. My diploma thesis gives some ideas for teachers for usage of the tools at schools, e.g. collection of exercises set together...

Ethical problems of the elderly when coming to terms with the imanence of death
Eberson, Arthur Markus ; Keřkovský, Pavel (advisor) ; Halama, Jindřich (referee)
In this thesis we will reflect on the ethical problems faced by seniors in their final phase of life. Old age and the time, when seniors must face the idea of near death, are associated with the whole complex of issues. The objective of this thesis is not only to describe some phenomena observed in this period of life, but it also objects to a comprehensive probe into the final period of the senior's lives. Therefore, at the beginning we will try to describe the various manifestations of aging and approaching the death so that we can monitor their development and changes, especially with regard to the psyche and social contacts. In the following section the ethical problems which the seniors have to face will be described, and we will think about the options of solutions to these ethical issues. Of course, we will also take into consideration the differences in the approaches of the seniors who are and are not believers. We will focus primarily on the ethical issues in terminal stages of the life and the ethical conflicts that are directly related to dying and the death. We won't disregard the question of euthanasia and controlled suicide, brief history of the problem will also be included. Of course, it will be discussed primarily in ethical and theological terms.

Characterization of recombinant fragment of an antibody against CD3 marker.
Písačková, Jana ; Maloy Řezáčová, Pavlína (advisor) ; Obšil, Tomáš (referee)
Monoclonal antibody MEM-57 recognizes CD3 antigen expressed on peripheral blood T-lymphocytes. CD3 surface glycoprotein complex associates with T-cell receptor and is responsible for the transduction of activation signal. Antibody MEM-57 has, therefore, a large diagnostic and therapeutic potential. It could be used in autoimmune diseases diagnostics, for classification of T-cell leukemias and, as an immunosuppressant, in transplantation. The most promising therapeutic use of MEM-57 antibody would be the construction of a "Bispecific T-cell Engager" (BiTE) antibody format with potential application in cancer therapy. In this format, single-chain variable fragment (scFv) of MEM-57 would be fused with an anti-tumor antigen scFv. The thesis is focused on biochemical and biophysical characterization of MEM-57 antibody scFv fragment. Recombinant antibody fragment scFv MEM-57, equipped with the pelB leader sequence, c-myc tag and His5 tag, was produced from a pET22b(+) vector into the periplasmic space of E. coli BL21 (DE3). Two-step purification protocol, employing nickel chelation affinity chromatography and ion-exchange chromatography, was developed to obtain high yield of pure protein. The antigen binding activity of scFv MEM-57 was confirmed by flow cytometry. Structural information on scFv MEM-57...

Project Preparation for Financing from EU Funds
Pagáčová, Iveta ; Hruška, Vladan (referee) ; Režňáková, Mária (advisor)
The Bachelor’s thesis approaches the possibilities of project co-financing using the financial resources from EU funds. The introductory chapter deals with the concept of EU regional policy, further there are particular European funds presented and connection to the Czech system of programme documents. The Fundamental, practical part of the thesis concerns with the selection of a suitable operational programme and the processing of materials necessary for the completion of the Grant Application Form. Particular steps that the applicant must accomplish before his application is passed are also mentioned as well as the conditions for the recipient of the grant.

Liability of a Contractor in the Contract for Work in Investment Construction
Kazdová, Hana ; Štenglová, Ivanka (advisor) ; Čech, Petr (referee)
71 Abstract Thesis, as the title suggests, is focused mainly on the liability of a contractor resulting from contracts for work concluded by parties in order to execute large industrial works. Capital construction is economically significant branch of industry both from national and international perspective. Czech law regulates capital construction, as far as private law is concerned, mainly by Commercial Code in it's articles dedicated to general regulation of contract for work. Capital construction requires sufficiently detailed contractual arrangements of mutual rights and obligations. Detailed arrangements concluded by parties are necessary due to the complexity, technical, technological, time, material, financial and personal demandingness of the subject matter of work along with long-term character of mutual relations and high risk of amendment of legislation. Thesis deals with usual arrangements of contracts concluded by parties in practice related to the liability of a contractor in capital construction. Besides the thesis displays the amount of risk the contractors bear and the scope of their liability in case of breach of the contracted obligations. The most important terms used in practice are described in the introduction of the thesis. These terms originate from formerly valid Economic Code,...

Phenotypic Analyses of the HD transgenic Minipig Model
Motlík, Jan ; Ellederová, Zdeňka
The transgenic model of Huntington’s disease in minipig (TgHD) was created in 2009 and information coding the sequence of N-terminal part of human mutated huntingtin was transferred to subsequent generations from both female and male sides. In each litter, transgenic (TgHD) and wild-type (WT) piglets were born in approximately equal ratio. At present, the Laboratory of Cell Regeneration and Plasticity keeps sets of animals in F2 and F3 generations with identical genetic background and bred in identical conditions of feeding and housing. The present research project was focused on a complex of non-invasive and invasive approaches to WT and TgHD minipigs to achieve the entire phenotypic analysis of HD progression in this large animal model.

Economic and social impacts of non-payment of alimony in legal theory and practice
Prachařová, Petra ; Pikola, Pavel (advisor)
Bachelor thesis will deal with the maintenance obligation of a parent to minors, that the first results of the Civil Code and later at the initiative of one of the parents addressed by the decision of the Court. The first part will explain the concept of non-payment of alimony, a glossary and its legislation. It will also indicate what impact can have and in most cases a failure to pay maintenance for a minor child and an authorized person. What financial and social problems they face this family and how complex and difficult situation for this family it is. And will also include options identify the beneficiary in the recovery and acquisition amounts due. It will also mention the earlier arrangement for the payment of maintenance replacement states that it subsequently exacted after the compulsory allowing authorized person and the minor child not suffer financially. The aim of this work will highlight solutions to the economic situation of these families in the form of re payment of maintenance replacement state.

Credit Constraints and Creditless Recoveries: An Unsteady State Approach
Derviz, Alexis
The paper investigates the behavior of credit demand and output arising from differences in productive capital sources in economies recovering from an adverse real shock. Beside physical capital, another form of capital – human capital – is available during the catch-up phase. Since a part of new physical capital must be debt-financed, whereas production is risky due to uncertain future total factor productivity, defaults happen with positive probability. The latter can be reduced by partially substituting physical capital for human, at a disutility cost. We ask whether a shift away from risky borrowed physical capital to human capital is able to generate a reduction in aggregate credit losses without too big a loss in output, thereby warranting a specific prudential policy. This question is addressed by means of a dynamic stochastic model with feedback decision rules, for which we develop a full-distribution numerical solution method. The long-term stationary limit distribution of the solution generalizes the steady state notion of deterministic models. Agents that start from relatively “poor” initial states are found to benefit from limits on unsecured borrowing at a very moderate cost in output terms, whereas for “rich” initial states, such limits prove to be largely redundant.
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