National Repository of Grey Literature 24,108 records found  beginprevious24099 - 24108  jump to record: Search took 1.37 seconds. 

First Aid to drowning People in the Place of Event
DUDOVÁ, Apolena
The theoretic part of the baccalaureate thesis is focused on providing first aid to drowning persons, on providing proper cardiopulmonary resuscitation, and on the possibility of using rescue and protective aids. This part explains principal causes of drowning, warns about places where drowning occurs most often, and indicates ways of prevention and safety. The purpose of the research part of the thesis was to determine whether the lay public has any theoretic knowledge of providing first aid to drowning persons. A quantitative method was used in the research part for data collection. The data was obtained using questionnaires, which were distributed to the lay public in the Uherské Hradiště region. The questionnaire was anonymous and included 14 questions. There was only one correct answer to every question. The questions were used to determine theoretic knowledge of first aid provision to drowning persons and theoretic knowledge of cardiopulmonary resuscitation. The hypothesis presumed that the lay public had theoretic knowledge in providing first aid to drowning persons. However, the opposite followed from the defined criterion used to prove or disprove the hypothesis and from the quantitative investigation results, i.e. that the lay public did not have theoretic knowledge in providing first aid to drowning persons. Thus the hypothesis was disproved based on the research. The lay public showed insufficient knowledge particularly of cardiopulmonary resuscitation procedures. The research concluded that the lay public should be more interested in the procedures and novelties in cardiopulmonary resuscitation, as well as in the basics of first aid. Also, acquaintance with first aid and cardiopulmonary resuscitation should be more and better available to the lay public. A solution could be offered by compulsory first aid courses for all professions, provided by employers on a yearly basis at least.

Human capital requirements in terms off the structural changes in the Czech Republic economy
Grušáková, Markéta ; Lapáček, Michal (advisor) ; Vostrovská, Zdenka (referee)
Nowadays there has been a great public and economic discussion about recent dynamics in the labour market in the Czech Republic. We enjoy a significant decrease in the rate of unemployment, some branches of the czech economy suffer from a qualified labour power deficiency. There are signals that educational and professional structure of unemplyed people do not meet the employers' demand for qualified workers. In the first, theoretic, part I classify sectors, branches and professions together with educational levels. I describe the theoretical backround of structural changes in the economy and its effects on the labour market. I focus also on an active employment policy. The second, practical, part examines how the educational level and qualiffication influence a possibility to acquire a job in The Czech Republic. I detaily focus on differences across regions in respect to acquired education. Further I analyze how former working experience influences a final decision about engaging the employee and if the current trend is to engage graduates or experienced employees. Another part of the labour market are labour offices and HR agencies. That is why I study the differences between these two institutions, especially the differences in their clientship, again in respect to acquired education. Final conclusion resulting from my findings illustrate the trends in the czech labour market according to the economic developement and continuing structural changes. Built upon my analysis I predict which occupations will enjoy a boom and which one starts to suffer a decline. Furthermore I suggest which educational branches support and which not because they produce a lot of not-engageable people.

The role of education in senior age
Kramperová, Eva ; Lorenzová, Jitka (advisor) ; Tvrzová, Ivana (referee)
ANOTATION The present work explores the role and significance of education in lives of the seniors. The thesis consists of two parts. The first part contains an overview of the topic's treatment in domestic literature, definition of basic terms and a description of selected aspects of the elderly's life, and an outline of lifelong learning system in the Czech republic. The second part is based on an empirical research and attempts to shed light at, as the title suggests, the role which education plays in lives of the czech elderly and significance it bears for them. Data for the analysis will be acquired through a combination of qualitative and quantitative methods (a telephone survey and in-depth interview). The work closes with relevant annexes and a list of resources used. KEY WORDS senior, senium, education, lifelong education, gerontopedagogy, motivation, meaning of life

Leiden mutation, its signification and methods of examination
FIALOVÁ, Kateřina
The subject of this thesis is Leiden mutation, its signification and methods of examination. This work deals with frequency of occurrence F V Leiden mutation in samples of examinants in the centre of laboratory medicine BioLab, spol. s. r. o., in Klatovy. Thrombophilia (hypercoagulation) is a genetic or acquired failure of hemostatic mechanistic system, which is connected with increased risk of the occurrence of thrombosis. The most important and the most frequent effect of thrombophilia is the venous thromboembolism. This concept means both deep venous thrombosis and/or pulmonary embolism and their development is always caused by several factors which are genetic or acquired. Mutation of factor V was described in 1993 as the resistance against activated protein (so called APC-resistance). It occurs most commonly as a genetic thrombophilia of white race where it can be found in 40% of patients with diagnosed thromboembolism. Leiden mutation in a gene for factor V is the most frequent predisposition for thrombosis. The risk of development of venous thromboembolism differs according as the fact if it is a heterozygotic or homozygotic carrier. Heterozygotic individuals are 7 times more riskly as for the development of venous thrombosis while the risk level in homozygotic individuals is 80 times. The rate of prevalence of FV Leiden mutation in the world ranges from 0 to 15 %. APC- resistance is caused by point mutation in the polynucleotide chain of a gene for factor V. Here it concerns the exchange of the nucleotide sequence respectively nitrogen basis of guanine and adenine for the position 1691 (G1691A). It creates a triplet which codes in position 506 in the place of amino acid arginine -Arg, R, glutamine -Gln, Q(R506Q). It causes resistance of the active factor V against protein C, which is to inactivate it. The factor V stays henceforth pro- coagulative and thus the creation of thrombin increases together with the risk of thromboembolic disease. The goal of this thesis was summarising of research findings related to the focused theme Leiden mutation, its signification and methods of examination, analyze whole blood samples of patients examined at Leiden mutation carrier status in the center of Laboratory Medicine BioLab, spol. s. r. o. in Klatovy and in consequence and then evaluate and interpret the results of the found out results. Carrier of FV Leiden mutation was observed in a group of patients of both sexes coming from Plzeň and Ústí nad Labem region using real-time PCR. Of the 169 patients examined 111 samples were obtained from women and 58 samples from men. Among women there were found 21 heterozygous carriers (18.9%) and 1 homozygous carrier of (0.9%) FV Leiden mutation. The male population was observed incidence of 17 heterozygotes (29.3%). None of the men did not hold the homozygous genotype FV Leiden mutation. Although the men were twice as frequent carriers of that mutation was not statistical analyzes demonstrated the effect of gender on the transfer FV Leiden mutation (P = 0.2).

The Tensile Test of Tubes
Janda, Luděk ; Císařová, Michaela (referee) ; Peterková, Eva (advisor)
The present thesis deals with the tensile test of tube samples and verifies the possibilities of obtaining the corresponding material characteristics. In this work, a total of 3 types of tube samples made according to ČSN EN 10002-1were investigated. For the experiments, longitudinally welded tubes made of 17 240 steel were selected. The used tube was marked as a thin-walled one. Tensile tests were performed on 22 the samples, namely 8 samples on samples having a form of a cut-off of a full cross section tube, 10 samples a strip of segment cross section and a 4 samples transverse cut-out of tube. The goal of thesis was to validate options of acquiring material characteristics, value of deformation hardening exponent ,,n,, and material characteristic ,,C,, of tube samples. Further examination was aimed at designating which shape of sample tubes used for tension test is most suitable. And behaviour of individual samples was examined with tensile load applied. Tension tests were conducted on hydraulic test machine ZD40.

The role of ABC transporter in clinical practise
Tornová, Petra ; Pávek, Petr (advisor) ; Čečková, Martina (referee)
The role of ABC transporters in clinical practice ATP-binding cassette (ABC) transporters are a family of transporter proteins that contribute to drug resistance via ATP-dependent drug efflux pumps. There are seven subfamilies classified as ABC transporters (ABCA through ABCG) that are expressed in both normal and malignant cells. They are involved in the transport of many substances, including the excretion of toxins from the liver, kidneys, and gastrointestinal tract, and they limit permeation of toxins to vital structures, such as the brain, placenta, and testis. The best-characterized transporter protein is MDR1/P-glycoprotein, and a number of clinical investigations have suggested that its intrinsic or acquired overexpression resulted in a poor clinical outcome of chemotherapy. Conventional cancer chemotherapy is seriously limited by the multidrug resistance (MDR) commonly exhibited by tumour cells. One mechanism by which a living cell can achieve multiple resistances is via the active efflux of a broad range of anticancer drugs through the cellular membrane. Various types of compounds and techniques for the reversal of ABC transporters mediated MDR have been developed, and efforts have concentrated on the inhibition of function and suppression of expression. Increased drug accumulation and...

Analysis of the appropriateness of the data from the IMU / GNSS units
Holouš, Karel ; Hanuš, Jan
The object of the air campaign Analysis of the IMU/GNSS data and it’s suitability, was to create a sufficient amount of GPS data to analyze the appropriateness of using the IMU/GNSS data for comparison with other IMU/GNSS data recorded at the same time by the ordering client. Based on the initial request data were acquired using the installed GPS sensors, on-board navigation system GARMIN G1000 and GNSS Applanix POS/AV 410. Data acquisition was performed during a single flight in total duration of 0:58 on February 16, 2016. During this flight we performed complete set of predetermined tests during different flight regimes.\n\n

Analysis of men and woman´s position in selected sectors of the national economy
Jahodová, Lenka ; Jindrová, Andrea (advisor) ; Jana, Jana (referee)
This thesis is closely focused on gender issues in terms of employment in sectors of national economy in the Czech Republic and the Moravian-Silesian Region. The theoretical part explains the basic concepts and definitions relating to gender, national economy and time series. In this work the progress of women and mens employment is monitored in Agriculture, forestry and fishing, Public administration and defense, as well as in the sector of Health and social care and Education. Predictions are made by using selected methods from the field of time series. The analysis is done on the basis of available data from the Czech Statistical Office in the period from 1993 to 2015. The final section focuses on the proposals and recommendations for future development.

The influence of longterm unemployment on work motivation
Tycarová, Iveta ; Chýlová, Hana (advisor) ; Josek, Mikuláš (referee)
For the bachelor thesis was chosen the topic "The influence of longterm unemployment on work motivation." Specifically, the issue of returning to work after maternity / parental leave. The reason for selecting the personal experiences of finding employment after maternity / parental leave and personal experience with the course "Education for women / men on maternity / parental leave". Also, nationwide importance of the topic and a certain marginalization. Bachelor thesis is focused on the unemployed in Rokycany in the Pilsen region. In this work, access to the statistics of the Labour Office Pilsen. From the statistics were obtained data on the unemployment situation in the region. The aim is to penetrate into the problems of parents returning to work after maternity / parental leave and assess what effect the return of a specialized course completion. This work compares success in finding jobs for the unemployed who have completed a specialized course and who does not. The data was electronically distributed among the participants of the above mentioned course through questionnaire survey, also part was filled with the long-term unemployed parents after maternity / parental leave, in cooperation with the Labour Office in Rokycany. On the basis of information obtained from the literature and from a personal investigation are drawn appropriate conclusions, tested set of statistical hypotheses and draw recommendations for practice.

The analysis of causes of the youth unemployment (15-24 age class) in European Union in years 2000-2015
Šulai, Michal ; Czesaný, Slavoj (advisor) ; Bartůsková, Lucia (referee)
The aim of this thesis was to analyze main causes of youth unemployment in countries of European Union. In order to assess main determinants of this negative phenomenon, an econometric model based on panel data was constructed. Source dataset, containing mainly Eurostat data, covers EU-28 countries in the 2000-2014 period. Results of a regression inclined that youth unemployment is effected mainly by overall economic development. Youth unemployment is more sensitive for economic downturns than unemployment in an adult age class. The model also suggested that cuts in payroll taxes and deregulation in the minimum wage legislation could have positive effect on youth employment. Based on the literature, reforms toward more practical and effective education system with elements of dual apprenticeship, could be also a positive step in tackling youth unemployment. However, an econometric-based proof of this hypothesis was not found.