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Reconstructive operations in spine region with bio-ceramic materials use
Lukáš, Richard ; Karpaš, Karel (advisor) ; Štulík, Jan (referee) ; Chaloupka, Richard (referee) ; Rudinský, Bruno (referee)
1. SUMMARY Introduction: During the period of the last 25 years remarkable changes occurred in the treatment of traumas of thoracolumbar spine. The surgical treatment was extended in cases where instability and impairment of its physiological shape are expected. This development is based on the progress in imaging technologies, more detailed understanding of spine biomechanics and a pathophysiology of its impairment. The situation was also influenced by the progression in surgical instruments and implants and also in the technology of bone substitutes. Aim of the study: The aim of the study is to analyze the long term morphological and clinical results after the surgical treatment of thoracolumbar fractures, in which the bioactive glass-ceramics in the form of granules was used as a bone substitute. Material and method: A series of 140 patients treated surgically for unstable thoracolumbar fracture (LSC points 4 - 6) during the period from 1997 to 2003 was studied. The average age of patients was 44 years (14 - 78). The patient collection consists of 83 males in the average age of 43,7 years (14-73) and 57 females in the average age of 44.9 years (15-78). The minimum follow-up was 24 months, the average follow-up period was 29 months. Patient series includes a group of 91 cases, in which the implant was...
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The influence of education according to working exercises of hard weakeyed disabled
Křivková, Zuzana ; Kovařovic, Karel (referee) ; Peliš, Michal (advisor)
Title: Work-preparation of hard visually impaired students in the special second schools. Objective: To give a comprehensive summary of the questions arising in employment of visually disabled persons in Czech republic, and in their preparation for work. Through a method of questionnaires investigate the quality of work-preparations in the special second schools in Czechrep. Method: The method in this research is questioning through questionnaires made for five special second schools for visually impaired in Czech rep. A specific questionnaire is created for the headmaster, educational adviser, teachers and for the students in the second half of their study. Results: This reports intention is to present the reader with all the relevant and useful information about the employment problem of visually disabled persons in Czech republic. The pieces of information given are actual responses to the presented situation. It was discovered that the level of preparation visually impaired gets in the special schools is good. The fact is that students are well prepared in light of subsequent integration into the society. They proved high measure of self-confidence, resolved to be of use in life.Their know-how is quite good, skills are accordant with their possibilities. Contingent absences (deficiencies) in...
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Computational methods in single molecule localization microscopy
Ovesný, Martin ; Hagen, Guy Michael (advisor) ; Plášek, Jaromír (referee) ; Fliegel, Karel (referee)
Computational methods in single molecule localization microscopy Abstract Fluorescence microscopy is one of the chief tools used in biomedical research as it is a non invasive, non destructive, and highly specific imaging method. Unfortunately, an optical microscope is a diffraction limited system. Maximum achievable spatial resolution is approximately 250 nm laterally and 500 nm axially. Since most of the structures in cells researchers are interested in are smaller than that, increasing resolution is of prime importance. In recent years, several methods for imaging beyond the diffraction barrier have been developed. One of them is single molecule localization microscopy, a powerful method reported to resolve details as small as 5 nm. This approach to fluorescence microscopy is very computationally intensive. Developing methods to analyze single molecule data and to obtain super-resolution images are the topics of this thesis. In localization microscopy, a super-resolution image is reconstructed from a long sequence of conventional images of sparsely distributed single photoswitchable molecules that need to be sys- tematically localized with sub-diffraction precision. We designed, implemented, and experimentally verified a set of methods for automated processing, analysis and visualization of data acquired...
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Creating of themes for an open-source eshop solution - Pretashop and a business plan for their distribution
Staš, Andrej ; Bruckner, Tomáš (advisor) ; Žamberský, Martin (referee)
The diploma thesis is based on the web Prestastyle.com that was founded in the first half of 2010. Initially it was a non-commercial project where users could find one free Prestashop theme that was ready for download and might be applied for eshop. (Prestashop is open-source solution for eshops) Due to personal reasons I stopped to build the project after short time. By this work I want to continue in the original intention. However, there should be more than just free themes. I want to offer also paid themes and modules of high quality so the users get valuable products. I describe the complete process of reconstruction of Prestastyle project -- setting the goals, analyzing of requirements, defining of users. As well, I present my business plan, which includes also a description of competitive sites and shows my advantages. Then I get to the technical solution and the realisation. There are variety of insights to problems I encoutered during the development. At the end I describe testing of the project and themes, I analyze results and compare them with the set objectives. I evaluate the final results and benefits of the work.
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Variant solutions reconstruction of airconditioning systems in the laboratory
Faltys, Michal ; Andrys, Petr (referee) ; Rubina, Aleš (advisor)
The diploma thesis deals with the designing and assessment of two variants of the reconstruction of the air conditioning system for the half of 3rd floor laboratory building BioVendor – Laboratorní medicína a.s. company. The system is proposed to fulfil hygienic, operational, economic and functional requirements for indoor microclimate of laboratories. The task of this system is the transport of fresh air to interior and the covering of heat gains in summer. The equipment is also designed for the regulation of air humidity in the interior. The theoretical part deals with the application of heat penetration of solar radiation double glazed construction. Calculating and project part deals with the specific proposal of two variants of a new HVAC system-level studies of which the selected variant is developed as the project documentation. Experimental part is devoted to measuring of CO2 concentration in operationally similar laboratory. The result of this work is to evaluate the operational and economic impacts on the choice of technically feasible options and implementation documentation selected option. The benefit of the experiment is to verify sufficient air exchange to ensure the optimum concentration of carbon dioxide in laboratories.
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Reconstruction of barn as a part of Miroslavské Knínice castle
Martínek, David ; Bažant, Zdeněk (referee) ; Strnad, Jiří (advisor)
The bachelor thesis deals with the reconstruction of a barn in Miroslavské Knínice. First, it was necessary to examine the conditions of the barn. Crumbling masonry and cracks in perimeter walls had been found, so it was necessary to create a design and assess new solutions to repair the barn. On the basis of these defects, it was proposed to pull down a half of the barn, including the foundations and proposed to lay concrete over this part of formwork together with reinforcement.
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Multipurpose Building in Rousínov
Grubl, David ; Novák,, Petr (referee) ; Vojtová, Lea (advisor) ; Kalousek, Lubor (advisor)
The basis of this bachelor‘s thesis is the architectural study completed in summer semester of the second year of my bachelor’s studies. The theme was to design reconstruction of the former post office and to design extension of a new multipurpose building. The location of the former post office and new extension is on the east side of Sušilovo Square in Rousinov, in Vyškov district. The idea was to combine appropriately former post office in baroque style with new extension. The former post office is on the list of cultural monuments of Czech Republic and is being dilapidated. During the reconstruction was designed some functional and layout changes and it was also necessary to replace the existing mansard roof, because of decaying insects. The new extension is a paraphrase of the classic rural gabled houses in minimalist‘s style and harmoniously complements Sušilovo Square. These 2 buildings will be linked by building connection with a flat roof, due to a operational purposes. Among the buildings is designed the half-atrium space, based on the historical context and offers a pleasant space to rest. In the former post office is designed a new housing, tourist information center with exhibition space. At the extension is situated a cafe on the ground floor with wonderful view towards Sušilovo Square and towards half-atrium space. Culture hall is located on the first floor with sanitary facilities for guests.The adjacent park on the east side of the former post office keeps the original trees and encourages passers-by to rest.
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Algorithm of imaging methods of injuries of the neck of the femur in the case of seniors
TOČÍKOVÁ, Miluše
The bachelor thesis deals with the incidence of femoral neck injury in the elderly. The work is divided into a theoretical and practical part. As the number of people of retirement age is growing, the rate of injuries associated with this age group has been increasing as well. It is necessary to accept the idea that age is a stage of human life, which every individual must eventually face. A femoral neck fracture is one of the causes of mortality and morbidity in the elderly. The incidence of this injury has been increasing both in developed countries and in the Czech Republic. A femoral neck fracture represents a threat for mobility and independence of seniors. Some people are then permanently dependent on mobility aids, while others remain in institutional care. The most common cause of femoral neck fractures in the elderly is a fall on their side, which is caused by a complex interaction of external and internal factors. The first imaging method used during a medical examination is sciagraphy, which is one of the oldest methods. It allows physicians to assess the preoperative condition of the hip joint and postoperative check-ups during the treatment by alloplasty or perioperative condition with the use of osteosynthesis. It is beneficial for the above-mentioned group of people to carefully assess the bone metabolism. A healthy bone is constantly reconstructed, it continuously breaks down and a new bone replaces it. With age, the degradation of bone prevails over bone formation and the bone begins to "thin". This disease is called osteoporosis. It is a disease that pertains to the civilisation diseases. It is often only diagnosed at an advanced stage, when it is already increasingly susceptible to fracture incidence. The factors of osteoporosis include an unhealthy lifestyle, hormonal changes in women after menopause, when there is a decrease in the level of calcium, a major weight loss etc. A painless, non-invasive method, by means of which a doctor can obtain comprehensive information about the amount of bone mineral in the examined part of the bone, is a densitometry test, or DXA. This test uses x-rays at two energy levels. The DXA method can be measured as a whole-body mineral content as well as any other part of the body. Other causes, which increase the risk of a femoral neck racture, are bone metastases. The proximal portion of the femur, including the femur neck, metastatically affects especially primary lung cancer, kidney cancer, thyroid, breasts in women and prostate in men. At an early stage, bone metastases are asymptomatic. Clinical symptoms such as pain can occur, when the metastatic process penetrates the periosteum and surroundings of the bone, thereby irritating the neural structures. Another symptom is the emergence of pathological fractures. Bone metastases are helping us uncover laboratory tests and diagnostic imaging methods, which include, for example, scintigraphy. Bone scintigraphy can detect a metastatic process much earlier than X-ray examination. The aim of the work was to describe the principles of individual imaging methods, which help doctors to determine the correct diagnosis, to learn more about the femoral neck injury in the elderly and about causes of their ocurence. Moreover, the two hypotheses were established: 1. The most frequently used method in case of a femoral neck injury is skiagraphic examination. 2. That is why more than a half of femoral neck injuries are diagnosed in the elderly. The practical part was elaborated on the basis of a quantitative research. The data needed for the research were obtained from case studies of patients hospitalized in the orthopedic department of the Hospital Tábor a.s., in the period from 1st April 2014 to 31st March 2015.
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STM study of adsorption of metals on the Si(111) 7x7 surface
Setvín, Martin ; Ošťádal, Ivan (advisor) ; Nehasil, Václav (referee)
The work is focused on studying of a single silver adatom hopping inside a half unit cell of Si(111)-7×7 reconstruction. It is possible to estimate activation energies and frequency prefactors for hops between particular adsorption sites. It was necessary to make fundamental modifications on a low temperature STM as a part of the work. The modificaations have been made on top of a sample cooling system and on inertial motor for coarse approach of the sample to a tip. The vacuum properties of the STM chamber have been improved. A considerable progress in technology of electrochemically etched tungsten tip preparation has been achieved. Further treatement of the tips has been studied with accent on field emission effect on the tip apex. The 7×7 reconstruction could not be prepared inside the vacuum chamber. Reason is probably a poor degassing of the sample. Further planned experiments could not be performed so far. This thesis contains detailed theoretical analysis of the studying of adsorption sites. The tests of time dependent tunelling spectroscopy method are described in results.
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