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Decreasing vaccination rate as a new global health problem
Galstyan, Elen ; Kučerová, Irah (advisor) ; Tesař, Jakub (referee)
This master thesis is focused on decreasing levels of vaccination as a new health risk. In recent years it has become a new trend that we can observe in European countries. Low vaccination levels amongst population are one of the reasons for new epidemics or pandemics happening. When immunization rises above 95 % then a collective immunization comes into effect. Collective immunization lowers the chances of diseases spreading. For this reason, World health organization supports immunization and tries to make immunization affordable reachable for everyone everywhere. This these analyses measles which can be stopped by vaccinating the population. Therefore, the World health organization prepares strategic plans aimed at eradication of this disease. Each member state has a task to apply these plans in their specific environment. This thesis focuses on the Czech Republic and its implementation of strategic plans happening 2005-2010 and 2011-2020. This thesis is structured into 5 chapters focused on theory of international relations, hesitancy to vaccinate, strategic plans of World health organization and the Czech Republic.
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Crisis management during the pandemic COVID-19
Nesvadba, Vojtěch ; Fiala, Miloš (advisor) ; Vilášek, Josef (referee)
Title: Crisis management during the pandemic COVID-19 Objectives: The goal of this thesis is to summarize circumstances which led to the declaration of the state of emergency and to describe the crisis management in the Czech Republic during the pandemic COVID-19. Methods: In order to work out this thesis, relevant study sources were searched and afterwards research of the study sources was done. Methods which are used in this thesis are descriptively-analytical. Results: The results of this thesis are summary information about the circumstances which led to the spreading of COVID-19 disease all over the world and primarily summary information about the crisis management during the pandemic COVID-19 in the Czech Republic. Keywords: Crisis, management, pandemic, epidemic
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The Spanish Flu Pandemic 1918/19 with particular reference to the Bohemian Lands and Central European relations
Salfellner, Harald ; Hlaváčková, Ludmila (advisor) ; Fialová, Ludmila (referee) ; Pock, Lumír (referee)
Charles University First Medical Faculty Study programme: History of Medicine Summary of dissertation The Spanish Flu Pandemic 1918/19 with particular reference to the Bohemian Lands and Central European relations Dr. med. univ. Harald Salfellner Prague, 2017 Summary Towards the end of the First World War, in 1918 and 1919, humanity faced a previously unparalleled flu pandemic; within a few months, more people had been killed than in all the battles of the 1914-18 war put together. The precise number of victims is unknown but is today generally reckoned at between 20 and 50 million. The whole world was affected by the Spanish flu, with the exception of a few remote islands, and Europe, already bled to death by industrialised warfare, was particularly hard hit. In summer 1918, the pandemic reached Bohemia in an early, relatively benign wave. A few weeks later, thousands were struck down in Prague in a second and far more deadly phase of the illness. In October 1918, as the First Czechoslovakian Republic arose from the ashes of the multiethnic Austrian state, and the masses celebrated in the cities, thousands of feverish patients were coughing behind drawn curtains, and facing an uncertain fate. In the USA, the flu pandemic - the greatest health disaster of the 20th century - has been the subject of many...
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"Media terrorism" via bacteria E.coli
Füleová, Veronika ; Šoltys, Otakar (advisor) ; Škodová, Markéta (referee)
The diploma thesis "Media terrorism via bacteria E.coli" puts the so-called cucumber affair from Summer 2011 into wider context and aims to discover the main attributes of contemporary risks and define the way they are presented in the media. Misguiding media releases and the inability to identify the source of the bloody diarrhea outbreak in Germany caused by E.coli bacteria have collectively had a significant impact on consumer behavior and economic stability on a global level. Most people are dependent on government and expert authorities due to the fact that they cannot recognize what represents a realistic threat and what serves as a basis for media sensation. This is why this thesis studies the social constructionist theory, basic media routines and practices as well as theoretical concepts that support the production of pseudo-events. A content analysis of selected Czech dailies and weeklies was executed in order to enable a comparison of the language that has been common for all "pandemics" in the 21st century.
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Assessing and Reducing the Impact of so called Black Swans in Launching New Medicines
Ženatá, Lucie ; Štohanslová, Barbora (referee) ; Adamec, Vladimír (advisor)
The diploma thesis is focused on the analysis and evaluation of risks in the introducing of new drug in the case of unexpected mass infections from the point of view of black swans. This thesis acquaints itself with the current state of the problematics, explains the terminology and meaning of black swans and gives examples of biological black swans. On the basis of the analysis and the available informations is proposed a risk assessment approach together with proposals how to reduce or eliminate possible risks.
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Flu viruses
Kaufmanová, Lucie ; Pavlasová, Lenka (advisor) ; Ehler, Edvard (referee)
This work deals with influenza viruses and the diseases caused by them. Influenza is one of the most common infectious diseases that annually affects nearly 10% of the world population during a pandemic, even 40 to 50%. Very often there are misconceptions that the flu is any involvement of the upper respiratory tract infections with accompanying fever and cough. The work is divided into two important segments. The first part deals with general characteristics of viruses, their inclusion in the taxonomic units, and building structural composition of viruses, as well as life cycle and the cycle of viruses in nature. The second part of the thesis summarizes existing knowledge regarding influenza; general definition, history, influenza viruses, including important 20th pandemic century, contains the epidemiological characteristics of influenza. It deals with the importance of vaccination, provides information about various types of vaccines. We can find an explanation of terms such as epidemics and pandemics, including the differences between them. Furthermore, in my work there are the most important organization involved in monitoring influenza surveillance concept itself. The work summarizes the main differences between the flu and other respiratory infections. Specifically, it focuses on different...
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Influence of sigle nucleotide mutations on influenza pathogenicity
Nitkulincová, Lucie ; Drda Morávková, Alena (advisor) ; Král, Jiří (referee)
Influenza virus caused several times the global concerns about the emergence of pandemics, in recent years. The most serious problem, in the fight against this virus, is its ability to quickly change its unusually antigenic specificity by reassortment and point mutations, especially in surface glycoproteins - haemagglutinin and neuraminidase. In this thesis I focused on point mutations in the hemagglutinin of influenza virus causing change in binding preference, which enables both influenza virus transmission between different hosts and unlimited proliferation in their tissues. The permanent change in amino acid sequence and thus the surface of hemagglutinin also largely prevents the host's immune system to destroy the virus efficiently and quickly enough to recognize when another infection. Each of the haemagglutinin subtypes has a different amino acid positions affecting its binding preference. Their summary is included in this thesis. Key words: influenza, single nucleotide mutations, pandemia, patoghenicity, hemagglutinin
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Pupils knowledges abou infectious diseases
Rančáková, Hana ; Drda Morávková, Alena (advisor) ; Erhart, Lukáš (referee)
A knowledge about infectious diseases and vaccination is very important in this time. The questionnaire, which is part of this thesis, is designated for 1st to 4th grade high school students and the upper grade grammar school pupils. The questionnaire was used to analyse pupils' knowledge and attitudes about infectious diseases and vaccination. Pupils' knowledge and attitudes are quite good and students are able to voice their opinion. Females have better knowledge than males and older students are better too. The thesis is further focusing on how are the infectious diseases included in the National Curriculum and examine the prevention programmes for schools. The other purpose is to follow up the threat of pandemic diseases and present state of knowledge and awareness about this topic.
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Preparedness of the Czech Republic for Pandemic Flu
JURZYKOWSKÁ, Lucie
Influenza illness occures masively in human population for centuries. Influenza is an acute disorder of viral origin. Currently influenza can be found all over the world. The viruses of influenza are circulating continously in all continents not only in the human population, but in animals too. Every year the population is affected by the seasonal epidemic of different magnitude. Influenza illness pose an important medical, social and economical problem. Next to the seasonal outbreaks occuring every year the influenza pandemic can appear after several tens of years. The pandemic of influenza would mean spread all over the world and it is caused by the new variant of the influenza virus. In past the influenza pandemics caused mortality of millions of people all over the world, high economical losses and social collapse of the states in the history. That´s why the particular states prepare their national pandemic plans. The early preparedness for possible influenza pandemic elaborated in the national pandemic plans and the measures following from the plans constitute a tool for reduction of extent, impact and outcomes of pandemic. The quality of preparedness can influence the economical functions of states, medical impacts of illness and final number of the victims. The aim of the dissertation is to compare the proposed measures responding to the influenza pandemic arising from the national pandemic plans of the Czech and Slovak Republic, to ascertain the state of preparedness to the influenza pandemic following from the pandemic plan of the Czech Republic and the situation in awareness of the civil population about the influenza pandemic in the Czech Republic. The theoretical part of the dissertation is focused on the epidemiological characteristic of the influenza illness. In the sphere of interest the issue of influenza pandemics is explained in terms of their history and the next field of the dissertation is focused on the pandemic plans. The research part of the dissertation is focused on the solution to the given research questions. Two research questions were specified to accomplish the defined aim: What are the differences between the approaches and measures in the pandemic plans of the Czech and Slovak Republic? What is the knowledge and awareness of civil population about the influenza pandemic in the Czech Republic? Regarding the issue the methodology the first research question included analysis of the content of the pandemic plans of the Czech and Slovak Republic and performance of the Checklist method in order to obtain an overview on approach, procedures and standard of preparedness in the territory of both states and possibilities their reciprocal comparison. Under the second research question the awareness and knowledge of the civil population about the pandemic influenza in the Czech Republic was investigated. For acquiring the data of researching study there was used The method of quantitative research was used to acquire the data for the research survey. The form of twenty questions was created. The first part of the questionnaire was focused on the general knowledge about influenza and the second part on the influenza pandemic and related measures. The respondents chose from the answers defined in advance. There wasn´t used the random sampling of the respondents. Fifty respondents from the non-representative sample filled out the form for acquiring the basic knowledge and finding out theoretical information about the influenza pandemic. Subsequently the statistical analysis was made from the obtained data using the methods of descriptive and mathematic statistic. It follows from the analysing results that the knowledge about the influenza illness and influenza pandemic exists among the civil population which means the laic public, but they are the lower extent and do not correspond to the normal frequency distribution.
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