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Safety Analysis of the Industrial Establishment.
Vlček, Zdeněk ; Rychlíková, Dagmar (referee) ; Tabasová, Andrea (advisor)
This thesis deals with the assessment of safety of an industrial complex. The thesis is divided into five chapters. The first chapter deals with basic information referring to an industrial complex and dangerous chemicals substances. The second chapter is devoted to the description of selective methods of CPR 18E. The third chapter is to identify risk sources of a serious accident in the industrial complex. The fourth chapter contains a general description of the HAZOP method. The last part represents a detailed analysis of risk sources of the serious accident by means of the HAZOP method and proposals for preventive measures.
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Factors Affecting Metabolism of Anthelmintics
Forstová, Veronika ; Skálová, Lenka (advisor) ; Machala, Miroslav (referee) ; Chládek, Jaroslav (referee)
Nowadays, anthelmintic therapy is the main method in the fight with parasitic worms. Anthelmintics, as well as other xenobiotics, undergo structural changes by effect of biotransformation enzymes, when lipophilic substances are transformed to polar substances more easily eliminable from the organism. Generally, biological effects of metabolites and parent compound are different. Activity of biotransformation enzymes is thus the fundamental factor influencing velocity of detoxification and elimination of the compound from the body and duration of drug effect as well. Modulation of biotransformation enzymes' activities can lead to changes in pharmacokinetic parameters of drug itself as well as other xenobiotics and thus to the risk of decrease in desired effect and/or increase in adverse effects with corresponding impact on the quality of drug therapy. In addition, possible risk of drug residues' presence in animal products has to be considered in farm animals. Biotransformation of xenobiotics is affected by many physiological as well as pathological factors. These factors can be divided into inter-individual (species, gender, genetic polymorphism) and intra-individual (age, diet, medication, disease, etc.). All these factors cause wide variability in occurrence and activity of biotransformation...
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Centra sdílených služeb v české veřejné správě –přínosy a rizika jejich implementace
Pelikánová, Šárka ; Vostrovská, Zdenka (advisor) ; Khorel, Tomáš (referee)
The baccalaureate thesis examines shared service centres, their implementation in the Czech public services administration and the related risks. The goal of this thesis is to provide an overview of the shared service centres, their role within the public service administration with a focus on the consequences of their implementation for the Czech public service administration. The first chapter describes the international competitiveness prospects of the Czech Republic for 2012-2020, as well as the Effective Public Services Administration project which supports the implementation of shared service centers. The second chapter examines the potential for optimization of institutional processes with a focus on shared service centres and the various types of support services most commonly provided by these. The third chapter describes the public services shared service centres implementation process which took place in Austria and the Netherlands, followed by an analysis and comparison of the Czech, Austrian and Dutch public services administration. The fourth chapter provides an outline of the current shared service centres implementation status in public service administration, as well as the author's view of some of the expected resulting advantages and risks. The thesis is based on information obtained from available literature, internet sources, a case study on the implementation of shared service centres by the Dutch Ministry of Justice, data made public by SAP, Eurostat and OECD.
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Hazard analysis of nanoparticles in the workplace environment and design of protective measures against their side effects
Skřehotová, Marcela ; Tesařová, Eva (advisor) ; Mráz, Jaroslav (referee)
The diploma thesis is focused on so called new risks, which currently include the risks associated with various nanomaterials - their production, introduction into practice and use. The paper summarizes the up-to-date knowledge about the characteristics of nanoparticles used and it proposes a procedure to estimate potential consequences of their exposure. The experimental part of the paper is represented by a case study, which introduces the practical application of the proposed procedure aiming at estimated exposure to nanoparticles on the workplace where metal working is executed and resulting occupational risks. The aim of this part of the study was to measure selected parameters of aerosols using a special measuring system working on the principle of laser photometry combined with diffusion charger and detector using Faraday cage. The object of the measurements was to determine the numerical concentration of nanoparticles present in working environment and the representation of size groups of submicron particles. The measurement procedure was designed in accordance with ČSN EN 689, ČSN EN ISO 16000-1 and ČSN ISO 8756 standards and data gained were subsequently interpreted. Afterwards the results were used to design the measures to reduce the risk of health damage when facing chronic inhalation...
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Risk factors for osteoporosis - knowledge and behavior of adolescent girls
KVASNÍKOVÁ, Martina
The thesis deals with the theme of risk factors for osteoporosis, knowledge and behavior of adolescent girls. The theoretical part of the thesis is divided into four chapters. The first chapter deals with the anatomy and physiology of bone. The second chapter discusses general information about osteoporosis. The third chapter summarizesthe prevention of osteoporosis and in the fourth chapter describes the treatment of osteoporosis. In the practical part of thesis was used method quantitative research. The target group consisted of 100 adolescent girls in the age range of 15-17 years of grammar school and vocational school in the České Budějovice. The girls were interviewed using a questionnaire, which consisted of questions related to osteoporosis. In thesis were determined two main objectives. The first of them was to map the knowledge of adolescent girls in the prevention of osteoporosis. The second objective is concerned with mapping the behavior of adolescent girls in the prevention of osteoporosis. The first research question dealt with by what kind of knowledge adolescent girls in the prevention of osteoporosis. The second research question was focused on the behavior of adolescent girls in the prevention of osteoporosis. According to the questionnaires can be concluded that the majority of respondents are not sufficiently informed about osteoporosis, but I find girls that basic information about the disease they have. Questionnaires filled in by teenage girls from the first and second years of grammer school and vocational school, therefore, the results are compared with one another. The survey shows that respondents from vocational school awareness of osteoporosis do not. Girls from grammer school have heard about this disease, but they can´t define it. The reason for this ignorance is that girls (from grammer school and from vocational school) have never been informed about osteoporosis. This fact mention the majority of the respondent girls. In most cases in the families of the respondents there is not osteoporosis or the girls do not know. On the following questions in the questioannarire girl (from both schools) have marked mostly option "not know". It were a questions whether sex hormones protects to some extent against osteoporosis. Furthermore, for which persons osteoporosis frequently occurs, whether the osteoporosis relate with calcium and vitamin D, or not. Schoolgirl from grammer school and vocational school mostly said that they consume milk and milk products several times a day or once a day. Of the 100 respondents sonly 18 girls said that do not drink alcohol. A total of 55 female students do not smoke and 23 female students smoke. The number of girl who smoke from vocational school is more than number of girls from grammer school. Schoolgirls of grammer school correctly think that physical activity can affect osteoporosis, the respondents of vocational school hold a different opinion. All of the girls regularly do sports, except for the two girls who do not purposefully movement. Based on the information from the questionnaire it would be appropriate that the teenager girls should be more informed about osteoporosis. There are several variations, such as educational material prepared for teenage girls or classes in school or self studying. Very important is the prevention of osteoporosis. The important role have a adequate nutrition and physical activity. Therefore, it is necessary to increase the knowledge of adolescent girls about the disease, so they can avoid.
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Why Do the Poker Players Deal More Often on High Stakes Than on Low Stakes Tournaments? Poker Deals Case.
Rytíř, Miroslav ; Špecián, Petr (advisor) ; Koubek, Ivo (referee)
This thesis aplied tools of economic analysis on situation in poker, where players choose to finish tournament or make a deal and take certain amount of money immediately. Theoretical frame consists of economic theories for decesion under risk and poker literature. Hypotheses are tested with regresion analysis on dataset which I obtain by my own observing. Estimations support hypothesis that players are risk-averze and loss-averze. In bigger tournaments are bigger prizepools and that is the reason, why players in bigger tournament make deals more often. Moreover deal is more likely, when players are approximetly equal skilled in poker.
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BYOD implementation issues analysis
Dula, Josef ; Vencovský, Filip (advisor) ; Pelant, Pavel (referee)
This bachelor thesis deals with Bring Your Own Device (BYOD) topic. The first part is topic definition and characteristics and also statement of benefits and risks bound up with. Risks are listed with possible solutions. Further on, the thesis focuses on mobile device management and enterprise mobility management. This part introduces the reader with management systems description and their functionality. The goal of the work is not only BYOD and management systems introduction, but also development of methodical approach to enterprise mobility management system selection. This approach can be afterwards used when deciding which management system solution to implement in the business. Stated methodical approach is demonstrated with practical presentation with Customs Administration of the Czech Republic.
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Procedures proposal for the implementation of the CRM system in the selected segment
Štofan, Dávid ; Fortinová, Jana (advisor) ; Pour, Jan (referee)
The aim of this thesis is to describe the procedure of the customization and implementation of SEM CRM system to the specific car company. Clarify the specifics of CRM in the automotive industry, to highlight the possible complications and risks that may occur during the process and propose a procedure to minimize the risks in consequent implementations in the future. To be able to fully understand these issues, it needs to be clarified and described in CRM (Customer relationship Management). This will be included in the theoretical part, which also includes development, architecture, solution design and implementation of CRM methodology. The practical part describes the procedures of implementation and customization of CRM into a specific car company . This section will also cover all the risks and problems that are encountered in the implementation and recommendations how to eliminate these risks.
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Application of quantile autoregressive models in minimum Value at Risk and Conditional Value at Risk hedging
Svatoň, Michal ; Baruník, Jozef (advisor) ; Vošvrda, Miloslav (referee)
Futures contracts represent a suitable instrument for hedging. One conse- quence of their standardized nature is the presence of basis risk. In order to mitigate it an agent might aim to minimize Value at Risk or Expected Shortfall. Among numerous approaches to their modelling, CAViaR models which build upon quantile regression are appealing due to the limited set of assumptions and decent empirical performance. We propose alternative specifications for CAViaR model - power and exponential CAViaR, and an alternative, flexible way of computing Expected Shortfall within CAViaR framework - Implied Expectile Level. Empirical analysis suggests that ex- ponential CAViaR yields competitive results both in Value at Risk and Ex- pected Shortfall modelling and in subsequent Value at Risk and Expected Shortfall hedging. 1
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