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Epidemiological aspects of inflammatory rheumatic diseases and diffusional diseases of binding tissue.
Hánová, Petra ; Pavelka, Karel (advisor) ; Bencko, Vladimír (referee) ; Horák, Pavel (referee)
v anglickém jazyce Introduction: No information was known about frequency of common inflammatory disorders in rheumatology in the Czech Republic. Aims of the study: To estimate the standardized annual incidence (INC) and point prevalence (PREV) of six diseases (rheumatoid arthritis-RA, juvenile idiopathic arthritis-JIA, gout, psoriatic arthritis-PsA, ankylosing spondylitis-AS, reactive arthritis-ReA) in a population-based study in two regions of the Czech Republic (CR). Methods: INC: Incident cases were registered on condition that the definite diagnosis was confirmed according to existing classification criteria during the study period. PREV was studied on the basis of identification of established diagnoses at a time point. Crude rates were standardized for age and sex. Results: Both INC and PREV are shown per 100.000 inhabitants. RA INC:31 (95%CI 20-42), PREV:610 (95%CI 561-658). Gout-INC:41 (95%CI 28-53), PREV:300 (95% CI 266-334). JIA-INC: 13 (95% CI 1-20), PREV:140 (95%CI 117-280). PsA-INC:3,6 (95% CI 1-8), PREV:49 (95%CI 40-60). AS-INC:6 (95% CI 3-11), PREV:94 (95% CI 94-109). ReA-INC:9 (95% CI 6-15), PREV:91 (95% CI 78-106). Conclusion: This is the first population-based study estimating annual incidence and prevalence rates of the most common rheumatological disorders in the Czech...
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Group exercise with elements of Pilates method in individuals with ankylosing spodylitis - comparison with control group
Bendzová, Pavlína ; Levitová, Andrea (advisor) ; Majorová, Simona (referee)
Title: Group exercise with elements of the method Pilates in individuals with ankylosing spondylitis - comparisons with the control group Objective: Find impact of group therapy with engaging Pilates method to movability of axial system, functional status, activity of disease and total health status of individuals with ankylosing spondylitis. Compare this method with compensation group motion program in individuals with ankylosing spondylitis. Methods: 26 individuals with ankylosing spondylitis of average age (38,25 ± 9,18) attending Institute of Rheumatology in Prague were chosen. Probands were split into two groups: experimental group, which were doing motion program with elements of Pilates (n=13), and control group, which were attending compensation group motion program in individuals with ankylosing spondylitis. It was empirical quantitative research, exactly comparative quasiexperiment, where was compared individual groups in between (inter-group) and, moreover, influence of individual motion programs (intra-group). Data gathering was executed twice - at the beginning of quasiexperiment (pre-test) and at the end (3 months after; post-test). Those parameters were examined: Bath Ankylosing Spondylitis Metrology Index for axial system region and expansion of chest, Bath Ankylosing Spondylitis...
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Case study of physiotherapy treatment of the patient with the diagnosis of ankylosing spondylitis.
Reinišová, Zuzana ; Vomáčková, Helena (advisor) ; Jarošová, Hana (referee)
Title: Case study of physiotherapy treatment of the patient with the diagnosis of ankylosing spondylitis. Objective: The main target of this bachelor's thesis was to take up with the issue of the ankylosing spondylitis, as the rheumatic disease and to outline the possibilities of its treatment. The next target was the elaboration of the case study of the patient with this diagnose, followed by the appraisal of the therapy's effect. Methods: In the general part is concerned with the Ankylosing spondylitis issue, namely with its symptoms, manifestations, methods of examination and a subsequent treatment of this disease. The second, special section of this bachelor thesis is focused on the individual patient with ankylosing spondylitis, physiotheapy assesment, subsequent therapy and the final effect of it. Results: The results of the physiotherapeutic care of the patient were observed to be positive in objective (clinical) and subjective way. The painful situations became milder and the patient assumed a positive approach to the kinesitherapy, which she didn't have till now. Keywords: case study, ankylosing spondylitis, pain, physiotherapy, treatment, movement.
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Population differences in the distribution of HLA-B27 allele in ankylosing spondylitis
Lennerová, Tereza ; Hušáková, Markéta (advisor) ; Novota, Peter (referee)
Ankylosing spondylitis (AS) is a chronic inflammatory disease affecting mainly the spine and the sacroiliac joints. This disorder has a genetic background and is strongly associated with HLA-B27 gene which occurs in about 90 % of patients. The prevalence of ankylosing spondylitis usually correlates with the frequency of HLA-B27. The strength of association HLA-B27 with AS varies between different populations and is also distinct for individual alleles of HLA-B27 gene. Some alleles can increase a risk of ankylosing spondylitis while others may have a protective effect. This work deals with the population differences in the occurrence of HLA-B27 alleles and their relation to development of ankylosing spondylitis. Key words: ankylosing spondylitis, HLA-B27, allele, subtype, population differences
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Comparison of educational and compensation exercise programmes for ankylosing spondylitis patients
Levitová, Andrea ; Strnad, Pavel (advisor) ; Bartůňková, Staša (referee) ; Bečvář, Radim (referee)
Title: Comparison of educational and compensation exercise programmes for ankylosing spondylitis patients Objective: The objective of the research was to determine the effect of two educational and compensation exercise programmes on the mobility of the axial system, the functional status and disease activity (including inflammatory process activity) in individuals with ankylosing spondylitis. Methods: The research group included men and women (average age of 35.42 ± 7.15 years), all out-patients of the Institute of Rheumatology in Prague. This characteristic sample (n ═ 38) consisted of respondents who were randomised into three groups: The first experimental group (n ═ 13) attended an educational and compensation exercise programme in a group setting in a gym (twice a week) and an educational and compensation exercise programme in the form of a group exercise in a pool - hydrokinesiotherapy (once a week); the second experimental group (n ═ 13) attended the same educational and compensation exercise programme in a group setting in a gym (twice a week); the control group educational and compensation exercise programme in a group setting in a gym (twice a week) received no exercise intervention but its members were allowed to use "passive" physiotherapeutic procedures (e.g. hydrotherapy or...
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Biomarkers of subchondral bone damage caused by inflammation in axial spondyloarthritis.
Bubová, Kristýna ; Pavelka, Karel (advisor) ; Horák, Pavel (referee) ; Hrnčíř, Zbyněk (referee)
Background: Axial spondyloarthritis (axSpA) is a chronic inflammatory rheumatic disease affecting primarily the spine and its adjacent structures. The disease is characterized not only by destructive joint changes but also by excessive osteoproduction, which can lead to gradual ankylosis of the spine and thus significantly reduce the mobility and quality of life. The pathogenesis of the disease is not yet fully understood, but a strong genetic background is suggested, along with dysregulation of tissue metabolism resulting from an imbalance of pro- and anti-inflammatory immune mechanisms. We are still lacking biomarker with sufficient sensitivity and specificity which could help to identify early diagnosis, to monitor subchondral damage, and to differentiate rapidly progressing patients. The aim of this work was to determine the levels of potential biomarkers of connective tissue metabolism, fat metabolism and new promising biomarkers for both disease subtypes, their relationship to disease activity and progressive structural changes. Results: We have shown increased serum/plasma levels of connective tissue metabolism biomarkers (especially matrix metalloproteinase mediated metabolites), which were able to differentiate patients with early and late forms of axSpA from healthy individuals (HC), were...
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Physiotherapy and life quality promotions patients with Bechterew disease
Strašáková, Anežka ; Zinková, Iva (advisor) ; Michalčinová, Klaudia (referee)
IN ENGLISH Name of title: Physiotherapy and life quality promotions patients with Bechterew disease Abstract: Subject of this bachelor's thesis is lifelong rheumatic disease - ankylosing spondylitis - from the perspective of patients and possible influence of physical therapy on disease's outcomes. Theoretical part deals with anatomical findings on axial skeleton, classification of ankylosing spondylitis within the group of rheumatic diseases, ethiopathogenesis, clinical manifestations, course of disease based on pathological and anatomical changes, examination, diagnostics, possibilities of medical treatment and therapy. Therapy is independant chapter, posing the first objective of this bachelor's thesis - description of different physical therapy approaches that can support the quality of life of patients with ankylosing spondylitis. Practical part deals with examination and description of subjective perception of quality of life of patients with axial form of ankylosing spondylitis during the course of disease. This bachelor's thesis can be classified as a descriptive type. Semi-structured non-standardized interview was used for data collection in practical part. Patients, who fulfilled criteria and signed informed consent, were interviewed. Recorded interviews were authentically transcripted....
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The case study of physiotherapy treatment of a patient with the diagnosis of ankylosing spondylitis and after resection of femoral head and femoral neck
Janovská, Kateřina ; Reckziegelová, Petra (advisor) ; Zinková, Iva (referee)
Title: The case study of physiotherapy treatment of a patient with the diagnosis of ankylosing spondylitis and after resection of femoral head and femoral neck Summary: The bachelor thesis is focused on the issue of rehabilitation treatment after rheumatic surgery resection of femoral head and femoral neck indicated due to ankylosing spondylitis disease. It consists of two parts - general and special. The general part includes theory of ankylosing spondylitis disease, its etiology, clinical presentation, diagnostics and treatment options, and rheumatosurgery of hip joint. The special part is focused on physiotherapeutic treatment of a patient with ankylosing spondylitis disease and after resection of femoral head and femoral neck. The case study of the patient was based on four-week practice in Institute of rheumatology in Prague in January and February 2020. Keywords: rheumatology, ankylosing spondylitis, physiotherapy, rheumatic surgery, hip joint
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Casuistry of physiotherapeutic treatment of a patient with ankylosing spondylitis diagnosis and in the condition after total hip replacement
Kohoutová, Eva ; Reckziegelová, Petra (advisor) ; Zinková, Iva (referee)
Title: Casuistry of physiotherapeutic treatment of a patient with ankylosing spondylitis diagnosis and in the condition after total hip replacement Aim: The aim of this bachelor thesis is to become acquainted and deepen the knowledge regarding the issue of total hip arthroplasty and ankylosing spondylitis as well as repeating the acquired skills I've gained during the study of physiotherapy at the UK FTVS in the practical part of my thesis. Summary: This bachelor thesis is devided into general and practical part. The theoretical knowledge of hip joint and ankylosing spondylitis are summarised in the general part of the thesis. I was describing joint construction, osteoarthritis, coxarthrosis, conservative and surgical treatment of coxarthrosis and the follow up care after the total hip arthroplasty. In the theoretical issue of ankylosing spondylitis, I focused on the clinical picture, treatment, therapy and possible performances of this disease. The practical part is describing the case report of the pacient, contains initial kinesiological analysis, short- term and long-term therapeutic plan, the process of individual therapeutic meetings, the output kinesiological analysis and evaluation of therapy results. Keywords: physiotherapy, total hip arthroplasty, ankylosing spondylitis
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The case study of physiotherapy treatment of a patient with the diagnosis of ankylosing with rhizomelic disability and after left hip joint replacement surgery
Cvachová, Adéla ; Novotná, Irena (advisor) ; Zinková, Iva (referee)
Title: The case study of physiotherapy treatment of a patient with the diagnosis of ankylosing spondylitis with rhizomelic disability and after left hip joint replacement surgery Author: Adéla Cvachová Summary: The bachelor thesis is focused on the issue of rehabilitation after rheumatic surgery of the left hip joint, indicated from rheumatic ankylosing spondylitis disease with rhizomelic disability. It consists of two parts - theoretical and practical. In the theoretical part, the thesis deals with the etiology of genesis, diagnosis clinical presentation, treatment options for ankylosing spondylitis and problematice of rheumatosurgery of the hip joint. The practical part is focused on physiotherapeutic treatment of the patient after total hip replacement with ankylosing spondylitis taken into account. The case study was based on four weeks praxis in the Rheumatology Institute in Prague in January 2019. Key words: case study, ankylosing spondylitis, rheumatic disease, rheumatosurgery, hip joint replacement, physiotherapy Name of diagnosis: M45 Ankylosing spondylitis
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