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Analysis of drug administration by nurses in health facility XIV
Newaldová, Sandra ; Doseděl, Martin (advisor) ; Rejmanová, Anna (referee)
Analysis of drug administration by nurses in health facility XIV. Author: Sandra Newaldová Tutor: PharmDr. Martin Doseděl, Ph.D. Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University Introduction: Medication errors are one of the causes of adverse events in healthcare facilities, leading to patient endangerment or harm. A study looking at this issue reports that the most common errors occur when a nurse administers medicines in a healthcare facility. Aim: The aim of the thesis is to monitor medication errors of nurses during the preparation and administration of medication to patients and to analyse the prevalence of medication errors, determine their type, their relationship to other influencing factors, and their severity with respect to the patient's condition. Methods: Prospective observational study with direct observation method, conducted in a specialized medical rehabilitation facility. The study included two pre- and post- intervention phases in which nurses' medication and procedural errors were monitored, analysed and evaluated. Observations were conducted in each phase over three days each time during morning, midday and evening administration. The results were analysed in programs Microsoft Excel and Wolfram Mathematica. Results: The...
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Analysis of drug administration by nurses in health facility IX
Blažková, Kateřina ; Doseděl, Martin (advisor) ; Košťálová, Barbora (referee)
Analysis of drug administration by nurses in a health facility X Author: Kateřina Blažková Tutor: PharmDr. Martin Doseděl, Ph.D. Department of Social and Clinical Pharmacy, Faculty of Pharmacy, in Hradec Králové, Charles University Introduction and aims: Currently, patients are treated primarily through pharmacotherapy. As a consequence of this fact, an ever-increasing incidence of medication errors can be expected. Medication errors and the resulting adverse events can have adverse consequences for the patient and, consequently, for the entire healthcare system. The aim of this study was to analyse the whole process of drug administration by nurses in inpatient wards in a South Bohemian hospital. Methods: This thesis is part of an ongoing research project involving the Faculty of Pharmacy of Charles University. The first data collection took place in 2021, followed by interventions towards nurses, doctors and hospital management. The data collection for this work was similarly conducted using the direct observation method for three consecutive days from 2 to 5 May 2022. Using a trained multidisciplinary team consisting of a pharmacist and a nurse, the internal medicine, surgery and aftercare departments were observed. Morning, midday and evening medication administration was observed in each ward....
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Analysis of drug administration by nurses in health facility XI
Altmannová, Tereza ; Doseděl, Martin (advisor) ; Dvořáčková, Simona (referee)
Analysis of drug administration by nurses in health facility XI Author: Tereza Altmannová Tutor: PharmDr. Martin Doseděl, Ph.D. Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University Introduction and aim: Medication errors are intrinsically linked to the practice of the medical profession. They can occur at several levels - prescription, drug preparation, dispensation, administration, and subsequent use of the drug by the patient. Nurses play an important role in the process of the drug administration in a hospital setting. Because of the occurrenceof medication errors and the consequent inability to achieve desired health outcomes, efforts are nowadays made to detect and minimize them. The aim of this study was to detect and analyze medication errors occurring during drug administration by nurses in a healthcare facility in South Bohemia. Methodology: The study is a part of a multi-year project involving the Faculty of Pharmacy of Charles University. The methodology is based on an observational study. The data collection took place in April 2022. Three hospital wards were assigned for the observation, where morning, midday and evening drug administration was monitored for three consecutive days. Data were recorded on a pre- generated form based on the...
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Analysis of drug administration by nurses in health facility XII
Gröszlová, Anna ; Doseděl, Martin (advisor) ; Malý, Josef (referee)
ANALYSIS OF DRUG ADMINISTRATION BY NURSES IN HEALTH FACILITY XII Author: Anna Gröszlová Supervisor of the thesis: PharmDr. Martin Doseděl, Ph.D. Charles University, Faculty of Pharmacy in Hradec Králové, Department of Social and Clinical Pharmacy Introduction: Medication administration in healthcare facilities significantly affects patient's safety. Observing and analyzing this process provide information about medication administration errors and the factors influencing them. As a result of observational findings, we can create interventions to improve the administration process. Aim: The aim of this work was to describe and analyze medication administration errors in a healthcare facility. Methods: The direct observation method was used for observation. Data collection took place in three departments (surgery, neurology, follow-up care) in 2021 and 2022. In both years, collection took place in each department on 3 consecutive days. Morning, midday and evening medication administration was monitored. An electronic database was used for recording. Data evaluation was done in Microsoft Excel and data from 2021 and 2022 were analyzed together. Nurse's work practices and medication errors were evaluated. Results: In total, 1160 drug administrations to 114 patients were observed. The largest number of...
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Study of in vivo toxicity of selected compounds with the implementation of the invertebrate model galleria mellonella
Záveská, Veronika ; Konečná, Klára (advisor) ; Janďourek, Ondřej (referee)
6 ABSTRACT Charles university, Faculty of Pharmacy in Hradec Králové Department of Biological and Medical Sciences Study program: Pharmacy Author: Veronika Záveská Supervisor: RNDr. Klára Konečná, Ph.D. Title of thesis: Study of in vivo toxicity of selected compounds with the implementation of the invertebrate model Galleria mellonella Background: The aim of this diploma thesis was to monitor the influence of the weight of the larvae, or rather its developmental stage, on the results after the administration of selected doses of DMSO. In the experimental work, the toxic impact of DMSO on larvae was evaluated not only from the point of view of mortality. Much attention was also paid to the characteristic features that are commonly observed during tests on Galleria mellonella larvae, such as the degree of melanization, the impact on activity and cocoon formation. Methods: For individual experiments, three test groups of six individuals each were created based on weight, one group of larvae weighing 250 ± 10 mg, the second group weighing 350 ± 15 mg and the third group weighing 450 ± 15 mg. Using a Hamilton syringe, a volume of 10 µl of the test solution with the appropriate concentration of DMSO was administered to each larva directly into the haemocoel through the last left proleg. The administered doses...
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Analysis of drug administration by nurses in health facility III
Novosadová, Aneta ; Malý, Josef (advisor) ; Šorf, Aleš (referee)
1 Abstract Analysis of drug administration by nurses in a health facility III Author: Aneta Novosadová Tutor: doc. PharmDr. Josef Malý, Ph.D. Consultant: Mgr. Ondřej Tesař Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University Introduction and aims: The drug administration by nurses is one of the most important part of a nursing care performed on daily basis. The goal of this master's thesis was to analyze the drug administration by nurses to the patients hospitalized in the internal, surgical or aftercare wards in one of four health facilities in the South Bohemian region with an emphasis on medication errors and their prevention. Methods: This is a part of an extensive observational and intervention study, which is conducted between years 2020-2023. The thesis demonstrates the data acquired by a direct observation of drug administration to the hospitalized patients from 19th to 25th July 2021. The data were collected by teams composed by a pharmacist and a nurse. The collected data were as follow: patients' personal data (e.g., age, gender, list of all drugs used by patient), data about the nurse who administered drugs (age, gender, length of working experience), data of the drug administration (the way of identification of the patient; the nurse's hygiene...
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Analysis of drug administration by nurses in health facility I
Sládková, Zuzana ; Malý, Josef (advisor) ; Šorf, Aleš (referee)
Analysis of drug administration by nurses in a health facility I Author: Zuzana Sládková Tutor: doc. PharmDr. Josef Malý, Ph.D. Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University Introduction and aims: Drug administration is one of the riskiest part of nursing. The aim of this thesis was to analyze the drug administration by nurses to the patients hospitalized in four hospitals in the South Bohemian region. Methods: The data for this observational-interventional study were collected from June to August 2021 in four hospitals (surgical department, internal medicine department, aftercare department), during three consecutive days in each department.The data were collected by a trained team consisting of a pharmacist and a nurse using direct observation. The following parameters were observed: information about the patient (e.g. gender, age, pharmacotherapy), information about the nurse (e.g. gender, education, length of practice), data related to drug administration (e.g. hygiene, patient identification, the right drug, the right patient, the right strength, the right dose, the right time, handling the medicine, the drink used to take the drug, drug administration in relation to food). The data were anonymized, transferred into the web database and...
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Analysis of drug administration by nurses in health facility VI
Brandová, Adéla ; Doseděl, Martin (advisor) ; Kostřiba, Jan (referee)
Analysis of drug administration by nurses in health facility VI. Author: Adéla Brandová Tutor: PharmDr. Martin Doseděl, Ph.D. Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University in Prague Introduction: The goal of rational pharmacotherapy should consist of the use of efficient, safe, and cost-efficient medication. The achievement of the said goals may be complicated by medication errors. Medication errors originate from human mistakes and intervene in all activities related to drug management, including drug administration. Aim: The aim of this study was to identify and analyze drug administration medication errors in a healthcare facility. Methods: The data was collected from the 29th of September to the 13th of October 2021, in a hospital located in the Hradec Králové region. Three departments were chosen for observation. Those three departments were surgery, internal ward, and follow-up care ward. The morning, midday and evening drug administrations on three consecutive days were monitored in each of the departments. This data collection was performed by direct observation. All of the routes of drug administration were monitored except intravenous drugs. Particular attention was paid to the identification of the patient, hand hygiene of nurses,...
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Analysis of drug administration by nurses in health facility V
Parasotska, Yuliia ; Doseděl, Martin (advisor) ; Ťupová, Lenka (referee)
Analysis of drug administration by nurses in health facility V Author: Yuliia Parasotska Tutor: PharmDr. Martin Doseděl, Ph.D. Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University Introduction: Medication errors in the healthcare setting affect patients in terms of morbidity, mortality, medication side-effects and longer hospital stays. For this reason, the analysis and detection of medication problems make a significant contribution to improving patient care and increasing patient safety. Objective: To describe and analyse the most common medication problems encountered in a healthcare facility during administration of medication by a nurse. Methodology: A prospective multicentre observational study was conducted in July 2021 in a hospital in the South Bohemian region. Using the direct observation method, medication errors occurring during medication dispensing by a nurse were monitored in three wards of the hospital. Over six days, the research team collected data from selected hospital wards and entered them into an online database to further assess the problems encountered and prevention measures were developed using descriptive statistics. Results: During the study, 13 nurses administered a total of 1,544 medications to 82 patients in three...
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Analysis of drug administration by nurses in health facility IV
Slobodyanyk, Myroslava ; Doseděl, Martin (advisor) ; Malý, Josef (referee)
Analysis of drug administration by nurses in health facility IV Candidate: Myroslava Slobodyanyk Supervisor: PharmDr. Martin Doseděl, PhD. Background: Currently, more emphasis is placed on quality and safe health care. At the medical facility, the nurse is responsible for administration of medications. Mistakes that may occur during administration may reduce the quality of health care delivery. For this reason, is important to minimize the occurrence of these doubts. Aim: The aim of the diploma is to describe and analyze the most common medication errors occurring in medical facilities during drug administration by nurses. Methods: This is a prospective observational study using direct observation. Nurses were administered medication in three hospital departments in the Czech Republic. Data collection took place for three following days at the Department of Internal Medicine, Surgery and Aftercare in July 2021. The data are recorded in a form. After a joint discussion, all data was rewritten into online database. The data were then exported to MS Excel and analyzed by descriptive statistics. Results: The study included 75 patients and the administration of the drugs by 15 nurses was observed. A total of 1518 drug administrations were observed, including oral drug delivery (91.56%), injections...
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