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Atrioventricular Block in Children: Long-term Influence of Bradycardia on Cardiac Function and Indications for Intervention
Jičínský, Michal ; Janoušek, Jan (advisor) ; Klásková, Eva (referee) ; Vančura, Vlastimil (referee)
Introduction. Non-surgical complete atrioventricular block (CAVB) in children is a rare disease. In absence of physiological conduction from atria to ventricles, patients suffer from life-long bradycardia. As causal treatment is not available, the only option to alleviate clinical symptoms and prevent possible sudden cardiac death is to implant a permanent pacemaker (PM). Correct timing of PM implantation in asymptomatic children is often challenging and published data regarding this issue are scarce. In the light of potential complications of early PM implantation, it is desirable to postpone this treatment as much as possible. Aims. We aimed to create a model of natural history of non-surgical CAVB in children and to find risk factors predicting need for future PM implantation in these patients. Also, we aimed to evaluate the effect of cardiac resynchronization therapy in heart failure patients associated with left ventricular apical epicardial pacing. Methods: Retrospective analysis of a nation-wide cohort of paediatric patients with non- surgical CAVB between 1977 and 2016. Prospective case study evaluating the effect of cardiac resynchronization therapy in paediatric patients with heart failure associated with left ventricular apical pacing. Results. Progression of bradycardia in children with...
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Electromagnetic interference and pacemakers
Kulík, Jindřich ; Richter, Miloslav (referee) ; Havlíková, Marie (advisor)
This thesis deals with electromagnetic compatibility of implantable electro-medical devices using in cardiology. The main aim of this thesis is detection of the resistance of implantable pacemakers (PM) and implantable cardioverter defibrillators (ICD) to the electromagnetic interference. In the first part of this thesis, a function of the heart, which is necessary for understanding of PM and ICD operation, is described. The function and construction of PM and ICD is detailed in the theoretical part as well. The next part is focused on the electromagnetic compatibility. The next part is description of the measurement method and the experimental arrangement used for practical experiments with electromagnetic resistance of PM and ICD.
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Microcontroler based On Demand Pacemaker
Daniš, Václav ; Balogh, Jaroslav (referee) ; Sekora, Jiří (advisor)
Pacemakers have nowadays become an inseparable part of treatment in a wide range of cardiovascular diseases. The topic of this bachelors degree paper refers to and proposes the implementation of a functional type of ´On Demand´ pacemaker controlled by a microcontroller. The introductory chapters focus on a more detailed, theoretical familiarization with the complex issues of permanent heart cardiostimulation. In addition to the actual theory of pacemakers and cardiostimulation, the chapters also include those significant historical aspects in the evolution of permanent cardiostimulation, the basic structures of heart anatomy and the transmission system of the heart. Also included are the recording of heart activity and ECG analysis, both physiological and pathological. In the practical part of the paper I deal with the ´On Demand´ pacemaker controlled by a microcontroller with a firm (solid, strong, steady, fixed) repeating frequency inhibited by the R wave. Subsequently, a proposed system for its implementation is created. The next step is the creation of a scheme for the electrical connections and composition of the microcontroller programme. The final part illustrates the implementation of the model of the pacemaker itself, preceded by a verification of the efficacy of the connections in a non-solder field.
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Alternative sources of nuclear energy
Svoboda, Josef ; Zlámal, Ondřej (referee) ; Katovský, Karel (advisor)
In places where it is not possible to use conventional production and distribution of energy, autonomous sources take over. Most of autonomous sources use solar energy, wind energy and other renewable resources. For applications such as special missions into outer space the usage of conventional sources is not possible. Except for powering special satellites, unconventional nuclear sources are also used in autonomous unmanned objects located in distanced areas with extreme natural conditions. It is also used in unusual propulsions of ground, water and air machine. These vehicles are for example pacemaker powered by radioisotope source, submarines, aircrafts and other vehicles supplied by nuclear reactor of unconventional conception. In this bachelor thesis there are globally summarized questions connected with unconventional sources of nuclear energy with detailed description of chosen parts. This work is concerned with finding more efficient machinery for conversion of heat energy supplied by radioisotope decay to electric energy.
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Cardiac resynchronization therapy - Evaluation of biosignals and quality assessment of devices
Lipnická, Soňa ; Maryšková, Věra (referee) ; Bernard, Vladan (advisor)
This bachelor's thesis is essentially devoted to the therapy of cardiac activity, pacemakers, to their types, application, indications, contraindications, and technical processing of devices. In this bachelor's thesis, there is also included description of biosignals, that are measured in dependence on these devices. All measurements and observations are necessary for proper monitoring of the patient's health condition. Another objective of this bachelor's thesis is to collect clinical data, that are statistically evaluated and then the results are compared with physiological values. In conclusion, this bachelor's thesis proves the importance of the use of pacemakers in today’s health service.
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Design of the On Demand Pacemaker controlled by Microcontroller
Jarošová, Veronika ; Chmelař, Milan (referee) ; Sekora, Jiří (advisor)
The aim of this diploma work is the suggestion and realization of a cardiostimulator of „On Demand“ type operated by microcontroller. The work is structured on four thematic parts. For the correct suggestion of the whole system, firstly is necessary to understand correctly the cell’s electrophysiology and heart’s anatomy, inclusive the cardiology arrhytmia, which are adherent to cardiostimulators. The cardiostimulator is inhibited by the R-wave and is adaptive on a pulse rate of a source signal. The whole system is supplied by batteries and this supplying is taken into consideration. The network’s functionality is realized on the ECG simulator. There are suggested the suitable enhancements in discussion.
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Optimization of Distributed Network Flow Collector
Wrona, Jan ; Grégr, Matěj (referee) ; Žádník, Martin (advisor)
This thesis is focused on the optimization of distributed IP flow information collector. Nowadays, the centralized collector is a frequently used solution but is already reaching its performance limits in large scale and high-speed networks. The implementation of the distributed collector is in its early phase and it is necessary to look for solutions that will use it to its full potential. Therefore this thesis proposes a shared nothing architecture without a single point of failure. Using the above proposed architecture, the distributed collector is tolerant to the failure of at least one node. A distributed flow data analysis software, whose performance scales linearly with the number of nodes, is also part of this thesis.
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External pacemaker
Lank, Petr ; Rampl, Ivan (referee) ; Chmelař, Milan (advisor)
This master´s thesis deals with the problem of heart stimulation by using external pacemaker. Such external pacemaker is used for a short – time stimulation of patient to overcome the time before the implantation of such apparatus. The master´s thesis informs about the basic function of heart and possible heart disorders which are treated by pacemaker. Great deal of master´s thesis is devoted to the design of external pacemaker wiring. This section describes the possibilities of controlling the pacemaker, circuits for detection R-R interval, a design of output circuit eith regard to required of stimulation and pacemaker feeding. The program Pspice was used to check the functional appropriateness of designed circuits and it was successively simulated in a non - soldering field.
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Patient data trasfer over GSM
Pavliš, Jaroslav ; Dlouhý, Jiří (referee) ; Švrček, Martin (advisor)
This diploma thesis is concerned with possibilities of patient data transfer from a pacemaker or implantable cardioverter-defibrillator to physician over GSM. Theoretical part describes options of data transfer in GSM networks, data appropriate for sending and a structure of message is proposed. A device, that is able to send medical data in a form of SMS messages is designed and constructed. The device uses a Freescale MC68HC908GP32 microcontroller, character display with a Hitachi HD44780 controller and a cell phone Sony CMD-J70. The program for microcontroller is written in assembler for HC08. For tabular view of received messages, an application software for PC was created.
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Evaluation of heart arrhythmias
Šromová, Michaela ; Kozumplík, Jiří (referee) ; Provazník, Ivo (advisor)
The thesis is a brief description of the anatomy and electrophysiology of the heart. The thesis also describes the different types of electrocardiogram and cardiac arrhythmias with a description of their treatment. The next section provides design of a programme for the classification of selected types of arrhythmias, and three options for rhythm detection, using the length of RR intervals, finding extremes of P and R waves, measuring the length of intervals and heights of amplitudes. The practical part of this work was to create a rhythm classifier assigning appropriate treatment of arrhythmias, verification of its functions on the signals available from the library of arrhythmias and its evaluation.
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