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Possibilities of hippotherapy in spasticity therapy in children with cerebral palsy
VOLŠINSKÁ, Monika
This bachelor's thesis discusses the possibilities of hiporehabilitation of spastic paresis of lower limbs in children with cerebral palsy. In clinical practice, they are used for therapy concepts on a neurophysiological basis. The main methods are Vojtova reflexive therapy and the Bobath concept, which are irreplaceable for the rehabilitation treatment of DMO. In this work I focus on complementary therapy in the form of hiporehabilitation. This method uses repetitive, rhythmic and regular stimuli for the central nervous system. Summation stimuli subsequently plasticity of the brain and helps for greater effectiveness of the treatment. The theoretical part is focused on the issue of cerebral palsy. Introducing definition, causes and symptoms including central nervous system involvement system, which is manifested by increased muscle tension. Thesis therefore also describes origin and manifestations of spasticity and the scale that evaluates spasticity. Spasticity can be controlled by hiporehabilitation, which I introduce in detail in the theoretical part of my work. Methodical part describes the data collection procedures that are used for research. The practical part proceeds in the form of qualitative research of a case study in which two probands participated and were diagnosed with a spastic form of cerebral palsy. An input and output kinesiology analysis was performed for individual probands, which includes anamnesis, physical examination of aspects and palpation, goniometry, walking tests-TUG, 2MWT and 10MWT. The modified Ashworth scale was used to evaluate the spread of spasticity. The entire research took place during a one-week hiporehabilitation stay. The results of therapy were used to compare input and output kinesiology analysis, which shows a positive trends in the effect of the therapy. Both probands showed a slight improvement in stability and posture, walking speed and regularity. Positive influence on spasticity was reflected by a change in pelvic position and a slight increase in the range of motion of the lower limbs. Hiporehabilitation alleviated the symptoms of muscle hyperactivity and therefore represents an opportunity to extend physiotherapy in children with cerebral palsy.
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Study of stability of antimicrobial nanomaterials in different environment by HPLC
Janderová, Šárka ; Trachtová, Štěpánka (referee) ; Márová, Ivana (advisor)
This thesis deals with the preparation of nanomaterials (nanoparticles, nanofibers) with encapsulated active substances and the stability of these nanomaterials in different environments using liquid chromatography. The development and optimization of methods for monitoring the kinetics of release of encapsulated substances from nanomaterials into various environments play a key role in research aimed at their utilization in the pharmaceutical, food, and cosmetic industries, and also contribute to the development of new antimicrobial nanomaterials limiting antibiotic resistance. The theoretical part focuses on the characterization of nanomaterials (nanoparticles, liposomes, nanofibers, and combined nanomaterials). Another section of the literature review deals with natural (eugenol, carvacrol, curcumin, thymol, vitamin E) and synthetic (ampicillin, streptomycin) antimicrobial substances. The final chapter discusses the instrumental methods used for the characterization of nanomaterials and the evaluation of their stability, released, and degradation products. In the practical part, the antioxidant activity of selected substances was first monitored. Liposomes were prepared, and their stability and encapsulation efficiency were examined. An HPLC method for determining active substances was optimized. Subsequently, the gradual release of the mentioned active substances from prepared liposomes was monitored. Nanofibers were prepared using forcespinning, and their release into selected model environments was also analyzed. Distilled water with minimal ion and impurity content served as a model environment, as well as a physiological solution at 25°C, simulating the temperature of the human body surface, and a physiological solution at 37°C, characteristic of human body temperature. This analysis provides a comprehensive view of the behavior of prepared materials and their potential practical applications. In the final section, combined nanomaterials (based on nanofibers and nanoparticles) with encapsulated active substances were prepared. The gradual release of active substances and any potential synergistic effects were examined for these nanomaterials.
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Furniture in symbiosis with plants
Paterová, Eva ; Landa Filípková, Valentýna (referee) ; Tobola, Ondřej (advisor)
The master‘s thesis deals with the design of furniture that serves to connect interiors with nature, especially with plants. At a time when many of us spend most of our time indoors, there is a growing desire to incorporate nature into our homes and workspaces. This thesis analyses historical and contemporary trends in the design of furniture intended for plants and highlights the possibilities for their further development. The aim is to identify and overcome the existing shortcomings in current solutions and, based on this analysis, to propose an innovative prototype that better meets the current needs and aesthetic preferences of users.
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Stability of the Zero Solution of Stochastic Differential System
Klimešová, Marie
Stability of stochastic differential equations (SDEs) has become a very popular theme of recent research in mathematics and its applications. The method of Lyapunov functions for the analysis of qualitative behavior of SDEs provide some very powerful instruments in the study of stability properties for concrete stochastic dynamical systems, conditions of existence the stationary solutions of SDEs and related problems.
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Delay Difference Equations and Their Applications
Jánský, Jiří ; Hilscher, Roman Šimon (referee) ; Čermák, Libor (referee) ; Čermák, Jan (advisor)
Disertační práce se zabývá vyšetřováním kvalitativních vlastností diferenčních rovnic se zpožděním, které vznikly diskretizací příslušných diferenciálních rovnic se zpožděním pomocí tzv. $\Theta$-metody. Cílem je analyzovat asymptotické vlastnosti numerického řešení těchto rovnic a formulovat jeho horní odhady. Studována je rovněž stabilita vybraných numerických diskretizací. Práce obsahuje také srovnání s dosud známými výsledky a několik příkladů ilustrujících hlavní dosažené výsledky.
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Wideband transimpedance photodiode amplifier
Šťastný, Martin ; Roubal, Zdeněk (referee) ; Drexler, Petr (advisor)
This thesis deals with the design of transimpedance amplifier with high gain. There are described different principles of semiconductor sensors of optical signal. There is also a comparison of different methods of converting the photocurrent to voltage. It also discusses the design of an appropriate feedback capacitor in terms of stability in participation as a transimpedance amplifier. It examines the impact of non-zero currents flowing to the input operational amplifier circuit functionality and output offset compensation. Part of the thesis is a simulation that confirms the calculated values. The thesis also deals with the implementation of the receiver and the method of correct measurement of the cut-off frequency.
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Stability of Time Delay Feedback Controls of Dynamical Systems
Lovas, David ; Tomášek, Petr (referee) ; Čermák, Jan (advisor)
Tato diplomová práce pojednává o stabilitě zpětně-vazebných řízení dynamických systémů s časovým zpozděním, speciálně řízení mechanických oscilátorů. Dva základní druhy řízení jsou užity v lineárních systémech. Dále je zde ukázána synchronizace dvouprvkových systémů užitím zpětně-vazebných řízení. Práce se také zabývá funkcí v MATLABu pro řešení zpožděných diferenciálních rovnic.
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The Study of Biopolymers Stability Using Light Scattering Techniques
Kratochvíl, Zdeněk ; Sedláček, Petr (referee) ; Kalina, Michal (advisor)
The stability of chosen biopolymers (or simple carbohydrates and amino acids) was in-vestigated using light scattering methods. Samples were prepared by dissolving the sub-stance in deionised water or in diluted acetic acid. Firstly, the effect of increasing concen-tration on zeta potential was observed and the optimal concentration for the next measure-ments was determined. Afterwards, the stability and the molecular weight of used sub-stances were studied during long-time storage in different time intervals. It was found out that chitosan, CMC, hyaluronate and sodium alginate were subjected to degradation whereas increase of the molecular weight and the zeta potential was observed in case of BSA. In the end, the samples were exposed to several different external effects, namely the influence of different temperatures, UV radiation and increasing ionic strength. The results showed that rather higher temperature has a significant impact on biopolymers stability. However, used biopolymers were hardly affected by UV radiation except BSA whose molecular weight increased considerably. Decrease of the zeta potential absolute values and the molecular size usually occurred with increasing ionic strength. The change of molecular weight was not detected.
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