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Creativity of teachers in the educational process in primary school
Vítová, Lucie ; Zemková, Jaroslava (advisor) ; Valešová Malecová, Barbara (referee)
The diploma thesis "Creativity of teachers in an educational process in primary school" focuses on creativity of teachers, which is a prerequisite of every teacher in current education. The thesis is divided into two parts; theoretical and practical. The theoretical part focuses on general knowledge, which appertains to the questions of creativity in the work of the pedagogues. In this part, the important factors are also described, which help to lead to the creative approach in the teaching. One of these factors is using activating methods. These represent the main approaches of the pedagogues to teach creatively. The theoretical part is also focused on the position of the teachers in the process of school inclusion and on the appropriate teaching methods and strategies for inclusive education. The practical part focuses on activating methods in teaching. The investigative survey was carried out via questionnaire, and its main objective was to explore the extent of using activating methods by teachers at basic schools. It also looks at whether these methods are considered to be an appropriate instrument to the creative and effective mediation of the curriculum for all pupils, including pupils with special education needs. KEYWORDS Creativity, pedagogue, teacher, creative education, teaching...
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Study of the antipoliferative properties of the series of novel aroylhydrazone iron chelators
Vítová, Lucie ; Šimůnek, Tomáš (advisor) ; Jirkovská, Anna (referee)
Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Biochemical Sciences Candidate: Lucie Kolbabová Supervisor: Doc. PharmDr. Tomáš Šimůnek, Ph.D. Title of diploma thesis: Study of the antipoliferative properties of the series of novel aroylhydrazone iron chelators Aroylhydrazones are tridental lipophilic iron chelators with good cell-membrane permeability. In the last decades some compounds of this chemical group have been demonstrated to have a significant antiproliferative activity. Salicylaldehyde isonicotinoyl hydrazone (SIH), an aroylhydrazone with an oral availability, showed a significant antiproliferative activity in previous experiments in our laboratory as well as the ability to protect cells from the oxidative stress- induced damage. The main disadvantage of SIH is low stability caused by rapid hydrolysis of the hydrazone bond in aqueous environment. To deal with this issue, the Department of Organic and Inorganic Chemistry of the Faculty of Pharmacy (Charles University) designed and synthesized analogues of SIH, derived from aromatic ketones, which showed significantly improved stability in rabbit plasma in comparison with the parent SIH. The aim of this study is to expand the previous experiments and it is focused on further structure modifications of the...
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Study of the antipoliferative properties of the series of novel aroylhydrazone iron chelators
Vítová, Lucie ; Šimůnek, Tomáš (advisor) ; Jirkovská, Anna (referee)
Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Biochemical Sciences Candidate: Lucie Kolbabová Supervisor: Doc. PharmDr. Tomáš Šimůnek, Ph.D. Title of diploma thesis: Study of the antipoliferative properties of the series of novel aroylhydrazone iron chelators Aroylhydrazones are tridental lipophilic iron chelators with good cell-membrane permeability. In the last decades some compounds of this chemical group have been demonstrated to have a significant antiproliferative activity. Salicylaldehyde isonicotinoyl hydrazone (SIH), an aroylhydrazone with an oral availability, showed a significant antiproliferative activity in previous experiments in our laboratory as well as the ability to protect cells from the oxidative stress- induced damage. The main disadvantage of SIH is low stability caused by rapid hydrolysis of the hydrazone bond in aqueous environment. To deal with this issue, the Department of Organic and Inorganic Chemistry of the Faculty of Pharmacy (Charles University) designed and synthesized analogues of SIH, derived from aromatic ketones, which showed significantly improved stability in rabbit plasma in comparison with the parent SIH. The aim of this study is to expand the previous experiments and it is focused on further structure modifications of the...
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Creativity of teachers in the educational process in primary school
Vítová, Lucie ; Zemková, Jaroslava (advisor) ; Valešová Malecová, Barbara (referee)
The diploma thesis "Creativity of teachers in an educational process in primary school" focuses on creativity of teachers, which is a prerequisite of every teacher in current education. The thesis is divided into two parts; theoretical and practical. The theoretical part focuses on general knowledge, which appertains to the questions of creativity in the work of the pedagogues. In this part, the important factors are also described, which help to lead to the creative approach in the teaching. One of these factors is using activating methods. These represent the main approaches of the pedagogues to teach creatively. The theoretical part is also focused on the position of the teachers in the process of school inclusion and on the appropriate teaching methods and strategies for inclusive education. The practical part focuses on activating methods in teaching. The investigative survey was carried out via questionnaire, and its main objective was to explore the extent of using activating methods by teachers at basic schools. It also looks at whether these methods are considered to be an appropriate instrument to the creative and effective mediation of the curriculum for all pupils, including pupils with special education needs. KEYWORDS Creativity, pedagogue, teacher, creative education, teaching...
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