|
|
Retinal biometry for human recognition
Sikorová, Eva ; Kolář, Radim (referee) ; Odstrčilík, Jan (advisor)
This master thesis deals with recognition of a person by comparing symptom sets extracted from images of the retinal vessels pattern. The first part includes the insight into biometric issues, the punctual analysis of human identification using retina images, and especially the literature research of methods of extraction and comparison. In the practical part there were realized algorithms for human identification with the method of nearest neighbor search (NS), translation, template matching (TM) and extended NS and TM including more symptoms, for which MATLAB program was used. The thesis includes testing of suggested programs on the biometric database of symptomatic vectors with the following evaluation.
|
|
|
Nucleotide density for finding CpG islands
Sikorová, Eva ; Provazník, Ivo (referee) ; Maděránková, Denisa (advisor)
This bachelor thesis deals with searching for CpG islands in the DNA sequences using the nucleotide density vectors. The first part includes view of the DNA structure, the genetic information expression, more detailed analysis of CpG islands and primarily their detection methods. In the practical part the algorithm for graphical representation of nucleotides on the basis of their densities and detections of CpG islands of artificially created and real DNA sequences was realized in the MATLAB program. The thesis includes the analysis of twenty sequences with the expected content of CpGIs and the comparison of results between the created program and two search engines.
|
|
|
Synthesis and study of supramolecular properties of azaphthalocyanines usable as sensors
Sikorová, Eliška ; Demuth, Jiří (advisor) ; Kučerová, Marta (referee)
Charles University, Faculty of Pharmacy in Hradec Králové Department Department of Pharmaceutical Chemistry and Pharmaceutical Analysis Candidate Eliška Sikorová Supervisor PharmDr. Jiří Demuth, Ph.D. Title of ThesisSynthesis and study of supramolecular properties of azaphthalocyanines usable as sensors Azaphthalocyanines are planar aromatic macrocycles that were derived from natural porphyrins. The basic skeleton consists of four isoindole units which are linked at positions 1 and 3 by azamethine bridges, resulting in an extensive system of conjugated double bonds that give these compounds unique optical and electrical properties. Azaphthalocyanines are widely used as industrial dyes, conductors, photosensitizers in photodynamic therapy, fluorescence quenchers or fluorescence sensors, etc. The compounds synthesized during this thesis can be used as an interesting type of sensors for sensing coordination analytes in solution. That is why this work deals with the study of the supramolecular properties of the synthesized compounds, in particular the ability to form J-dimer type aggregates, which are formed by coordination of the peripheral pyridyl nitrogen to the central zinc cation of the second azapthalocyanine. J-dimers resemble a "step-like" arrangement in contrast to the second type of...
|
|
| |
|
| |
|
|
Synthesis and evaluation of antimycobacterial 1,3,4-oxadiazole derivatives
Šikorová, Enikő ; Krátký, Martin (advisor) ; Vinšová, Jarmila (referee)
Charles University, Faculty of Pharmacy in Hradec Králové Department of Organic and Bioorganic Chemistry Author: Enikő Šikorová Supervisor: doc. PharmDr. Mgr. Martin Krátký, Ph.D. Consultant: Mgr. Václav Pflégr Title of diploma thesis: Synthesis and evaluation of antimycobacterial 1,3,4-oxadiazole derivatives Tuberculosis (TB) is a serious infectious disease caused by obligately pathogenic rods of Mycobacterium tuberculosis complex (Mtb.), and it is still among the ten most common causes of death worldwide. One of the main complications of TB therapy is the ever-increasing resistance of mycobacterial strains to conventional drugs. Therefore, the development of new antimycobacterial compounds is crucial to overcome this issue. Research and development of new potential antimycobacterial agents often involve structure modifications of clinically used drugs - frequently the first-line drug, isoniazid (INH). The starting point of this work is also the structure of the already mentioned INH. First, a series of 2-alkyl-5-(pyridine-4-yl)-1,3,4-oxadiazoles and N'-acylisonicotinohydrazides as their synthetic precursors were prepared and evaluated with very promising activity (expressed as minimal inhibitory concentration - MIC) against several mycobacterial strains (MIC Mtb. H37Rv of 1-8 µM). Furthermore,...
|
|
|
Analýza chovu žirafy Rothschildovy (Giraffa camelopardalis rothschildi) v Zoo Ostrava
Sikorová roz. Valečková, Eliška
In 2014, a breeding group of giraffes was observed in Ostravian zoo. The aim of the observation was to monitor and evaluate individual activities of the animals during the day. The observation took place in both winter and summer season. Elements of behavior had been recorded for four days in each season and compared thereafter. The conclusion of the monitoring is that the most frequent element of behavior was food and water intake, followed by standing, walking and other motion, and often licking of other objects ocurred. Less frequent was excretion and the least frequent sexual behavior. Notes on morphology, bionomy, worldwide distribution, and quantities of giraffes in zoos are summarized and personal evaluation of breeding in Ostrava zoo is mentioned.
|
|
|
Nucleotide density for finding CpG islands
Sikorová, Eva ; Provazník, Ivo (referee) ; Maděránková, Denisa (advisor)
This bachelor thesis deals with searching for CpG islands in the DNA sequences using the nucleotide density vectors. The first part includes view of the DNA structure, the genetic information expression, more detailed analysis of CpG islands and primarily their detection methods. In the practical part the algorithm for graphical representation of nucleotides on the basis of their densities and detections of CpG islands of artificially created and real DNA sequences was realized in the MATLAB program. The thesis includes the analysis of twenty sequences with the expected content of CpGIs and the comparison of results between the created program and two search engines.
|
|
|
Retinal biometry for human recognition
Sikorová, Eva ; Kolář, Radim (referee) ; Odstrčilík, Jan (advisor)
This master thesis deals with recognition of a person by comparing symptom sets extracted from images of the retinal vessels pattern. The first part includes the insight into biometric issues, the punctual analysis of human identification using retina images, and especially the literature research of methods of extraction and comparison. In the practical part there were realized algorithms for human identification with the method of nearest neighbor search (NS), translation, template matching (TM) and extended NS and TM including more symptoms, for which MATLAB program was used. The thesis includes testing of suggested programs on the biometric database of symptomatic vectors with the following evaluation.
|
|
|
Retinal Biometry for Human Recognition
Sikorová, E.
This paper deals with recognition of a person by comparing symptom sets extracted from images of the retinal vessels pattern. In the practical part there were realized algorithms for human identification with the method of nearest neighbor search (NS), extended NS including more symptoms and template matching, for which MATLAB program was used. The work includes testing of suggested programs on the biometric database of symptomatic vectors with the following evaluation.
|
guest ::
RSS feed.