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Utilization of CTA and CTP in Middle Cerebral Artery Stroke
Cimflová, Petra ; Krajina, Antonín (advisor) ; Neuwirth, Jiří (referee) ; Procházka, Václav (referee)
Introduction: Diagnostic imaging has a crucial role in the diagnosis and therapeutic management of acute ischemic stroke (AIS). The main aim of this thesis was to further evaluate the utilization of CTA and CT perfusion (CTP) in the diagnosis and treatment decision in patients with AIS caused by the occlusion of the middle cerebral artery. Methods: Study in Chapter 2 evaluated the automatically derived CT perfusion lesion volumes (PLV) and hypoperfusion intensity ratio (HIR) with collateral score using multiphase CTA (mCTA) (Kruskal-Wallis, Wilcoxon rank-sum test and Spearman's rho correlation coefficients were calculated). In study in Chapter 3, the assessment of ischemic changes by expert reading and available automated software for non-contrast CT and CTP was compared (the sensitivity, specificity, positive and negative predictive value were calculated). In Chapter 4, the performance of StrokeSENS software tool in detection of anterior large vessel occlusions (LVO) was tested (receiver operator characteristics analysis). Study in Chapter 5 investigated whether prediction of clinical outcome and final infarct volume can be improved by collateral status assessment on time-variant color-coded mCTA (multivariable logistic regression). The aims in Chapter 6 were to determine if mCTA-derived tissue...
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Inflammatory bowel disease (Problems of chronic Illnes)
Hodásová, Zuzana ; Mellanová, Alena (advisor) ; Neuwirth, Jiří (referee)
This bachelor thesis is focused on the clients with chronic intestine disease that is Crohn disease and ulcer colitis.The thesis is divided into two parts - theoretical and practical. The theoretical part describes anatomy, history and characteristics features of the two non- specific disease. Second half of this part occupies with the quality of chronically ill person's life.The results of anonymous questionnare are arranged and later evaluated in the practical part as well as goals determination and hypotheses. At the end of bachelor thesis there are discussion and conclusion. Key words: Crohn disease ulcer colitis quality of life chronic Illnes client respondent
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Options computed tomography with high resolution in the diagnosis pulmonary complications in haematological malignancies
Mírka, Hynek ; Kreuzberg, Boris (advisor) ; Neuwirth, Jiří (referee) ; Heřman, Miroslav (referee)
Value of HRCT in the diagnostics of pulmonary complications of malignant haematologic diseases. Early diagnosis is one of the essential conditions for successful therapy of heamatologic malignancies and their complications. Imaging methods play an important role in their detection and patient's management. HRCT is the most contributing method in the diagnostics of pulmonary involvement, which is very common in this group of patients. The aim of this thesis was to find out the potential of this method in the diagnostics of pulmonary complications in patients with haematologic malignancy. For this purpose were assessed 4 objectives: 1) comparison between HRCT and chest X-ray; 2) determination of capability of HRCT to make a specific diagnose; 3) definition of indication criteria for HRCT and 4) assignment of the suitable examination technique. In the time period from January 2000 until December 2005 were performed 214 HRCT examinations of the lungs in the group of 162 patients with haematological malignancy and pulmonary symptomatology. 176 examinations were compared with chest X-ray, which was performed 48 hours or less before HRCT. Pulmonary lesion was discovered in 180 cases (84,1%). 123 findings were confirmed by another method (response to a specific therapy, cultivation, serology, BAL or...
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The violence on elderly in the Czech families
Hříbalová, Marie ; Cejp, Martin (advisor) ; Neuwirth, Jiří (referee)
There is no doubt that the human population is growing old worldwide. As a result we more often think about the ageing and the old age. One of the motives which is, however, connected with ageing is the rough handling, which may develop into maltreatment, abuse and neglect (it is known as the EAN syndrome - Elder Abuse and Neglect). In this graduation theses the authoress targets the violence on seniors in their own families. In this case the aggressor is their child, grandchild or another relative. The main aim of this study is to analyse the main cause which leads to EAN. This negative social phenomenon is described from the point of view of the employee of crisis phone line for seniors.
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EVALUATION OF BONE MINERAL DENSITY AND CALCIUM SCORE IN HEMODIALYSIST PATIENTS
Ohlídalová, Kristýna ; Kreuzberg, Boris (advisor) ; Neuwirth, Jiří (referee) ; Tůma, Stanislav (referee)
Origin of renal osteodystrophy and cardiovascular complications are multifactorial. This complications are caused by disorders of calcium - phosphate metabolism already at the beginning of patient's irreversible renal failure. The factors playing the most important part in the development o renal ostedystrophy and are hypocalcemia and increasing serum phosphate levels associated with a declining glomerulal filtration. Two main types of renal osteodystrophy can be described - high turnover bone disease and low turnover disease. High turnover forms of renal osteodystrophy are characterized by rapid bone turnover caused by abnormally high PTH levels. The two types of high turnover renal osteodystrophy are predominant hyperparathyroid bone disease, and mixed uremic osteodystrophy. Low turnover forms of renal osteodystrophy are characterized by a dramatic drop in the rate of bone remodeling, caused by oversuppression of PTH and/or by aluminum accumulation. The bones become thin and overly flexible, and bowing may occur. The two types of low turnover renal osteodystrophy are low turnover uremic osteodystrophy and aluminum-related bone disease. Patients who have end-stage renal disease with increased serum phosphate levels and calciumphosphate products are associated with an increased prevalence of ectopic...
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History of Nursing in Mladá Boleslav Region
Ulčová, Dita ; Pavlíková, Pavla (advisor) ; Neuwirth, Jiří (referee)
v anglickém jazyce This bachelor thesis investigates history of nursing in the region of Mladá Boleslav. The aim of the thesis is to shed the light on the history, development and the current state of nursing in the Mladá Boleslav region. The thesis is written from historical point of view. The thesis consists of five chapters. Chapter 1 describes the nursing care in prehistoric times and documents the prehistoric settlement of Mladá Boleslav. Chapter 2 focuses on the nursing in the Middle Ages and special attention is given to the formation of hospitals in Mladá Boleslav region. Chapter 3 describes the nursing from the period of Enlightment till the end of the First Republic. The chapter focuses on the cholera outbreak, the establishment of the military and district hospital and the psychiatric hospital. Chapter 4 discusses the nursing from the end of the World War II up to the present. The chapter analyzes the development of the district and psychiatric hospitals after the Second World War. Chapter 4 also looks at the establishment and the development of the nursing school in Mladá Boleslav. Chapter 5 puts forward the memories of nurses who worked in Klaudian Hospital in Mladá Boleslav. The development of nursing care in Mladá Boleslav is briefly compared with the overall developments in the...
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Patient with Alzheimer's disease Case study
Kramlová, Michaela ; Marková, Eva (advisor) ; Neuwirth, Jiří (referee)
v anglickém jazyce: Bachelor thesis deals with a summary of theoretical knowledge about Alzheimer's disease and nursing care for such a sick patient. The practical part was closer specifics of nursing care and evaluation of individual nursing diagnoses within the nursing process. Keywords: Alzheimer's disease, dementia, communication, nursing care, nursing process, therapy
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Inflammatory bowel disease (Problems of chronic Illnes)
Hodásová, Zuzana ; Mellanová, Alena (advisor) ; Neuwirth, Jiří (referee)
This bachelor thesis is focused on the clients with chronic intestine disease that is Crohn disease and ulcer colitis.The thesis is divided into two parts - theoretical and practical. The theoretical part describes anatomy, history and characteristics features of the two non- specific disease. Second half of this part occupies with the quality of chronically ill person's life.The results of anonymous questionnare are arranged and later evaluated in the practical part as well as goals determination and hypotheses. At the end of bachelor thesis there are discussion and conclusion. Key words: Crohn disease ulcer colitis quality of life chronic Illnes client respondent
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