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Ecotoxicological evaluation of the non-steroidal and anti-inflammatory drug
Horáková, Veronika ; Vytlačilová, Jitka (advisor) ; Karlíčková, Jana (referee)
Horáková Veronika, Ecotoxicological evaluation of the non-steroidal and anti- inflammatory drug, (graduation thesis) Charles University in Prague, Pharmaceutical Faculty in Hradec Králové, Department of Pharmaceutical Botany and Ecology; total number of pages: 67 There is getting more higher occurrence of residuals of healing substance connected with growing consumption of medicals in our environment, where they influence a range of organisms. In this work the ecotoxicity of diclofenac was monitored. Four tests of toxicity were selected for evaluation of this influence - one acute test (with Thamnocephalus platyurus), two semi-chronic tests (with Tetrahymena thermophila, Sinapis alba seeds) and one chronic test (with Brachionus calyciflorus). Values for diclofenac have been found from these tests: 24hEC50 5,058 mg/l - THAMNOTOXKIT FTM , 24h EC50 32,88 mg/l (23,07 - 46,86 mg/l) at 492 nm - more generation test with organism Tetrahymena thermophila, 48h EC50 1,363 mg/l (0,7848 - 2,366 mg/l) - ROTOXKIT F CHRONIC, 72h EC50 71,42 mg/l (62,51 - 81,60 mg/l) - a semi chronic test with Sinapis alba seeds. Key words: ecotoxicology, diclofenac, Tetrahymena thermophila, Thamnocephalus platyurus, Brachionus calyciflorus, Sinapis alba
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Experimental testing of reactivity of huzul horses
Horáková, Veronika ; Řezníček, Jan (advisor) ; Ehler, Edvard (referee)
This thesis experimentally tested the reactivity of 39 horses from which there were 19 huzuls, 10 Czech warmblood horses, 1 Noriker, 1 crossbreed of thoroughbred and Lipizzaner horse, 1 coldblood horse, 3 half-blood horses and 4 thoroughbreds. The objective of the thesis was to compare the reactivity of Huzul horses used for hippotherapy and training of children with a control group of horses used for recreational riding, and asses the suitability of huzul horses for use in hippotherapy from a reactivity point of view. During the test horses were presented with four objects (a moving and vocalizing toy of piglet, a mirror, an umbrella and a ball). Each of those was presented to the horse for 20 sec. The reactions of the horses to each of the objects were evaluated and used to calculate an avarage reactivity score for each horse. Based on the results of the statistical analysis, it was shown that the reactivity of the huzul horses used in hippotherapy and training of children was lower than that of the control group.
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Effect of Diclofenac on Autotrophic Organisms
Horáková, Veronika ; Vytlačilová, Jitka (advisor) ; Karlíčková, Jana (referee)
Abctract Mgr. Horáková Veronika, Effect of diclofenac on autotrophic organisms, (rigorous thesis) Charles University in Prague, Pharmaceutical Faculty in Hradec Králové, Department of Pharmaceutical Botany and Ecology Total number of pages: 67 A larger amount of medical substances and their influence on our environment are connected with their increasing consumption. This work is linked with the former dissertation on Eco-toxicological evaluation of non-steroid and anti-inflammatory medicaments and so for this reason there was spread the test spectrums of chronic toxicity of diclofenac. There were used The test of inhibition of germination seeds Lactuca sativa and The test of alga toxicity Desmodesmus subspicatus for assessment of chronic toxicity of diclofenac. There were found these values for diclofenac from these tests: The test of inhibition of germination seeds Lactuca sativa 72h IC50 0,16 mg/l (0,01 - 3,76 mg/l). The test of alga toxicity Desmodesmus subspicatus 72h IC50 671 nm: 41,30 mg/l (18,76 - 90,91 mg/l) and 750 nm: 23,60 mg/l (14,98 - 37,18 mg/l). Keywords: diclofenac, Lactuca sativa, Desmodesmus subspicatus
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Kinesiotherapy of elderly people who live in a retirements house
Horáková, Veronika ; Hátlová, Běla (advisor) ; Novotná, Viléma (referee)
Názevpráce Kinezioterapie u seniorů žijících v domově důchodců. Název práce v angličtině: Kinesiotherapy of elderly people who live in a retirements house. Cíl práce Hlavním cílem této diplomové práce je na základě praktických zkušeností formulovat použité přístupy u sledované skupiny klientů a pokusit se určit míru působení intervence na celkový psychický a fyzický stav sledovaných seniorů. Metoda K získání potřebných informací jsem použila metodu zúčastněného pozorování, neformální rozhovor a testování pomocí testů MMSE a Testu hodin. Zjištěné informace z testů MMSE a Testu hodin byly zpracovány a zaneseny do tabulky. Výsledky Výsledkyjsou zpracovány a zaneseny do tabulky. Reprezentují vliv kinezioterapie na seniory. Klíčová slova Stáří, demence, kinezioterapie, pohybová aktivita, MMSE, Test hodin. 4
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Effect of Diclofenac on Autotrophic Organisms
Horáková, Veronika ; Vytlačilová, Jitka (advisor) ; Karlíčková, Jana (referee)
Abctract Mgr. Horáková Veronika, Effect of diclofenac on autotrophic organisms, (rigorous thesis) Charles University in Prague, Pharmaceutical Faculty in Hradec Králové, Department of Pharmaceutical Botany and Ecology Total number of pages: 67 A larger amount of medical substances and their influence on our environment are connected with their increasing consumption. This work is linked with the former dissertation on Eco-toxicological evaluation of non-steroid and anti-inflammatory medicaments and so for this reason there was spread the test spectrums of chronic toxicity of diclofenac. There were used The test of inhibition of germination seeds Lactuca sativa and The test of alga toxicity Desmodesmus subspicatus for assessment of chronic toxicity of diclofenac. There were found these values for diclofenac from these tests: The test of inhibition of germination seeds Lactuca sativa 72h IC50 0,16 mg/l (0,01 - 3,76 mg/l). The test of alga toxicity Desmodesmus subspicatus 72h IC50 671 nm: 41,30 mg/l (18,76 - 90,91 mg/l) and 750 nm: 23,60 mg/l (14,98 - 37,18 mg/l). Keywords: diclofenac, Lactuca sativa, Desmodesmus subspicatus
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Ecotoxicological evaluation of the non-steroidal and anti-inflammatory drug
Horáková, Veronika ; Vytlačilová, Jitka (advisor) ; Karlíčková, Jana (referee)
Horáková Veronika, Ecotoxicological evaluation of the non-steroidal and anti- inflammatory drug, (graduation thesis) Charles University in Prague, Pharmaceutical Faculty in Hradec Králové, Department of Pharmaceutical Botany and Ecology; total number of pages: 67 There is getting more higher occurrence of residuals of healing substance connected with growing consumption of medicals in our environment, where they influence a range of organisms. In this work the ecotoxicity of diclofenac was monitored. Four tests of toxicity were selected for evaluation of this influence - one acute test (with Thamnocephalus platyurus), two semi-chronic tests (with Tetrahymena thermophila, Sinapis alba seeds) and one chronic test (with Brachionus calyciflorus). Values for diclofenac have been found from these tests: 24hEC50 5,058 mg/l - THAMNOTOXKIT FTM , 24h EC50 32,88 mg/l (23,07 - 46,86 mg/l) at 492 nm - more generation test with organism Tetrahymena thermophila, 48h EC50 1,363 mg/l (0,7848 - 2,366 mg/l) - ROTOXKIT F CHRONIC, 72h EC50 71,42 mg/l (62,51 - 81,60 mg/l) - a semi chronic test with Sinapis alba seeds. Key words: ecotoxicology, diclofenac, Tetrahymena thermophila, Thamnocephalus platyurus, Brachionus calyciflorus, Sinapis alba
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Kinesiotherapy of elderly people who live in a retirements house
Horáková, Veronika ; Hátlová, Běla (advisor) ; Novotná, Viléma (referee)
Názevpráce Kinezioterapie u seniorů žijících v domově důchodců. Název práce v angličtině: Kinesiotherapy of elderly people who live in a retirements house. Cíl práce Hlavním cílem této diplomové práce je na základě praktických zkušeností formulovat použité přístupy u sledované skupiny klientů a pokusit se určit míru působení intervence na celkový psychický a fyzický stav sledovaných seniorů. Metoda K získání potřebných informací jsem použila metodu zúčastněného pozorování, neformální rozhovor a testování pomocí testů MMSE a Testu hodin. Zjištěné informace z testů MMSE a Testu hodin byly zpracovány a zaneseny do tabulky. Výsledky Výsledkyjsou zpracovány a zaneseny do tabulky. Reprezentují vliv kinezioterapie na seniory. Klíčová slova Stáří, demence, kinezioterapie, pohybová aktivita, MMSE, Test hodin. 4
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Experimental testing of reactivity of huzul horses
Horáková, Veronika ; Ehler, Edvard (referee) ; Řezníček, Jan (advisor)
This thesis experimentally tested the reactivity of 39 horses from which there were 19 huzuls, 10 Czech warmblood horses, 1 Noriker, 1 crossbreed of thoroughbred and Lipizzaner horse, 1 coldblood horse, 3 half-blood horses and 4 thoroughbreds. The objective of the thesis was to compare the reactivity of Huzul horses used for hippotherapy and training of children with a control group of horses used for recreational riding, and asses the suitability of huzul horses for use in hippotherapy from a reactivity point of view. During the test horses were presented with four objects (a moving and vocalizing toy of piglet, a mirror, an umbrella and a ball). Each of those was presented to the horse for 20 sec. The reactions of the horses to each of the objects were evaluated and used to calculate an avarage reactivity score for each horse. Based on the results of the statistical analysis, it was shown that the reactivity of the huzul horses used in hippotherapy and training of children was lower than that of the control group.
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