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Epidemiological aspects of Lyme Borreliosis in Czech Republic
Fišerová, Tereza ; Janovská, Daniela (advisor) ; Čelko, Alexander (referee)
The aim of this bachelor work was to collect and to evaluate the data on the incidence of Lyme borreliosis in the Czech Republic in the last ten years (2003-2012). First, a comparison of the incidence of this disease in the administrative regions of the Czech Republic was made, which indicated noticeable differences between the regions. Then, the data for the South Bohemia Region and Vysočina Region were analyzed in a more detail to identify the main factors, which could contribute to the increased incidence of this disease. A brief history of the incidence of Lyme borreliosis worldwide and its etiology is also provided, together with an overview of its clinical manifestations and spread, as well as the corresponding laboratory diagnostic methods and methods of prevention.
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Possibilities of prevention reflecting geriatric principles: Functional status and depressivity in old age
Vaňková, Hana ; Čelko, Alexander (advisor) ; Dohnal, Karel (referee) ; Jirák, Roman (referee)
Possibilities of prevention reflecting geriatric principles: Functional status and depressivity in old age Hana Vaňková, MD Abstract Background: Given the population ageing in Europe and in the Czech Republic, strategies aiming to prevent functional decline in older age are of great importance. Depression in old age increases functional decline and is also associated with increased morbidity, mortality and deterioration of quality of life (Anstey et al., 2007; Karakaya et al., 2009). Therefore, there is a need for a comprehensive intervention addressing both functional status and depressive symptoms. Methods: Using comprehensive geriatric assessment, the relationship between functional status and depressive symptoms was examined in 308 residents of long-term care facilities (RCFs) in the Czech Republic. Depressive symptoms were measured using the 15-item Geriatric Depression Scale. An additional randomized control trial (RCT) evaluated the effect of a dance-based therapy on depressive symptoms in 162 institutionalized older adults with average age over 80 years. Results: A multiple regression analyses adjusted for sociodemographic factors and for taking antidepressants found that cognitive function and functional limitation by pain were most strongly associated with depressive symptoms. The ability to...
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