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The distribution of medicaments by the nursing sister in the social wealfare institutes
Havlínová, Petra ; Hošťálková, Monika (advisor) ; Marková, Iva (referee)
This bachelor's thesis focuses on the distribution of medication in the social welfare health institution. The objectives of the thesis were to focus on procedures of distributing medication by nurses and to introduce the most frequent complications when distributing the medication in the social care institute. The thesis is composed of two parts, theoretical and practical. The theoretical part describes social and health care services, a health and social care system, a general pharmacology, medicaments' distribution and the complications during the distribution, and the competency of nurses. The research part concentrates on individual study and describes a methodology of research and its organization. This research was done via survey, and the results are analyzed and discussed. Key words: social service, health service, healt-social care, distribution of medicaments, pharmacology, competence of nursis, complication
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Influence of body size and temperature on cardiac function in vertebrates
Špičák, Luboš ; Starostová, Zuzana (advisor) ; Marková, Ivana (referee)
Heart, as main driving unit of circulatory system of vertebrates, ensure a great number of body functions by constant circulation of blood in every individual. This body functions are provided by transposport of energy in various forms and by transport of chemical substances. Number of these body functions are absolutely necessary in each momemnt of the lifetime. If we describe metabolism as speed of all reactions in body, then circulatory system is one of the key means to reach it. Metabolic rate increases with two basic factors, body mass and body temperature. It's not proportional relationship, but allometric increase is conditioned by power law. In addition, this exponential relationship is limited, in case of body temperature, by temperature range specific for each living organism. It would be expected that changes in size of body and body temperature might have strong influence to quality and function of circulatory systém and heart itself. However, metabolism is significantly influenced by some another factors like quality of adjacent surrounding. Organisms belonging to vertebrates habitated great number of various enviroments and they developed lots of adaptations to survive there. This adaptations include significant changes in cardiac architecture and heart functions. The aim of this work...
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The role of protein kinase C in the pathogenesis of insulin resistance and its complications
Marková, Irena
Charles University in Prague, Faculty of Science Department of Biochemistry The role of protein kinase C in the pathogenesis of insulin resistance and its complications Mgr. Irena Marková Ph.D. thesis Supervisor: Doc. RNDr. František Novák, CSc. Faculty of Science, Charles University in Prague Department of Biochemistry Consultant Supervisor: Ing. Ludmila Kazdová, CSc. Institute for Clinical and Experimental Medicine in Prague Department of Metabolism and Diabetes Prague 2010 2 INTRODUCTION Metabolic syndrome (MS) represents a cluster of metabolic disorders that increase the risk of type 2 diabetes (DM2) and cardiovascular diseases [1]. The relevancy of MS is shown by its high prevalence and also by the fact that it plays a key role in the pathogenesis of many disorders, especially DM2, obesity, hypertension, cardiovascular diseases and others [2]. MS is characterized by tissue resistance to insulin action, hyperinsulinemia, impaired glucose tolerance and dyslipidemia, essential hypertension, abdominal (visceral) obesity, hyperuricaemia, coagulation disturbances and fibrinolysis, and endothelial dysfunction [3]. Insulin resistance (IR) is a basic metabolic abnormality of MS. It is a common pathological state in which target cells fail to respond to ordinary levels of circulating insulin [4]. It results in...
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Comparison of ecological requierements of the epiphytic species within Orthotrichaceae family
Franková, Hana ; Plášek, Vítězslav (advisor) ; Hejda, Martin (referee) ; Marková, Ivana (referee)
The thesis is a part of an ongoing research on taxonomy, ecology, and the distribution of epiphytic bryophytes particularly within the Orthotrichaceae family, based on collected bryofloristic records. The database now contains 6500 records. I have analysed interspecific differences in habitat preferences between species, namely their associations with particular phorophytes, pH of phorophyte bark, altitude, and the position on the phorophyte. Individual species differed in their occurrence according to altitude, phorophyte, and pH, though altitude was the most important factor. All analysed species have been shown to represent obligate epiphytes. Some species reveal a tendency to occur preferrentially on northern or western side of the phorophyte, but this tendency is not by any means universal. I discuss these findings in the context of the knowledge of species autecology and current changes in their distribution.
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The role of protein kinase C in the pathogenesis of insulin resistance and its complications
Marková, Irena ; Novák, František (advisor) ; Zeman, Miroslav (referee) ; Zídková, Jarmila (referee)
18 effects of TZDs are probably due to the remodeling of adipose tissue and increased adiponectin secretion. SUMMARY Studying the pathogenesis of insulin resistance and the role of PKC in insulin resistance In HHTg rats, elevated serum triglycerides and FFA were associated with the ectopic accumulation of triglycerides in tissues and reduced insulin sensitivity of peripheral tissues. Impaired glucose utilization in the peripheral tissues was associated with the reduced activity of GS in skeletal muscle. Decreased GS activity and glucose utilization in peripheral tissues indicate a possible defect in insulin signal transduction. In line with this, our results show that skeletal muscle IR was associated with the increased activation and translocation of PKC θ. Nutritionally induced obesity of HHTg rats resulted, in many cases, in the further deterioration of metabolic abnormalities associated with IR. We found that PKC θ, in particular, could contribute to the metabolic abnormalities associated with IR and obesity. The age-related increase in IR and deterioration of some parametres of carbohydrate and lipid metabolism, were not associated, in HHTg rats, with obesity but with increased serum levels of triglycerides and FFA. The age-related worsening of IR in HHTg rats was accompanied by increased...
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Knowledge of secondary school students in first aid in the region of Pribram
MARKOVÁ, Iveta
This thesis deals with the knowledge of high school students in providing first aid in the Příbram region. Providing first aid to the injured and saving their lives or health is a legal and moral obligation of all of us. There are many incidents that can cause serious or light injury. We should know the possible dangers, know how to act, and be able to provide first aid both to ourselves, to our closest, but to others as well. It is therefore necessary that the public is sufficiently educated in first aid so as to be able to respond adequately. In the Czech Republic it is necessary to include the subject of first aid into the school curriculum. Currently, however, neither teacher training in first aid is conceptually solved though the current legislation and related regulations generally prescribe training in first aid as an obligation for schools. Yet there are no specific standards or recommendations. The theoretical part of this thesis deals with the topic of first aid, with the high school educational system and the education of teachers. Subsequently, we present the integrated rescue system, basic first aid terminology, sudden severe illnesses and the care for the injured. An integral part of the chapter is a brief description of selected statistical methods. Through basic mathematical operations, descriptive statistics, and the use of tables and graphs, the theoretical part gives an account and summary of large amounts of data. Descriptive statistics is followed by mathematical statistics. It includes a nonparametric and parametric testing. In this thesis we have set the objective of determining the degree of knowledge and skills of Příbram region high school students in providing first aid and of comparing the skills and knowledge of health students and students of different study programs. We have set two hypotheses: H1: "More than 2/3 of all surveyed high school students in Příbram region will score more than 50% of correct answers on the survey," and H2: "health profession students will achieve better results on this survey than students of other disciplines." In order to achieve the defined objectives and to verify the hypotheses we have compiled a questionnaire focusing on the area of first aid, carried out a questionnaire survey, and conducted statistical surveys using descriptive and mathematical statistics. The questionnaire consisted of closed questions. Three questions were of generally informative character and twenty questions focused particularly on the problems of first aid. There were four response options to the questions focused on first aid, only one of which was correct. By a random selection we picked out four out of fourteen secondary schools and the High School of Nursing and College of Health Příbram, hereinafter SZŠ. The project involved 295 students, a total of 154 girls and 141 boys, specifically 147 SZŠ students and 148 students from other high schools. The selective statistical sample consisted of 100 students of SZŠ and 100 students from other high schools. The questionnaire survey covered the period from March to May 2015. From the survey results it is clear that the surveyed knowledge is slightly above average in SZŠ students and reaches the average level in students of other high schools in Příbram region. The arithmetic average of the SZŠ students was 16 points out of 20 and only 13 of 20 points in students from other high schools. Only 13% of students achieved less than 50% of the correct answers. The results of the survey show that the objectives of the thesis were met and both hypotheses were confirmed. Nonetheless, a question arises: "Are the teachers adequately trained in first aid?" The answer follows from the incorrect answers of students. The results of the survey have been provided to the participating high schools which then could focus on potential problems in the area of first aid and their curriculum.
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Risk flood analysis
Marková, Ivana ; Dráb,, Aleš (referee) ; Duchan, David (advisor)
This thesis deals with the processing maps of flood hazards, threats and risks based on available data in accordance with Directive 2007/60/EC and the methodology of the Ministry of Environment 2011 on the selected flow Kyjovka at kilometer 49,156 to 54,698.
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Multicriteria flood analysis
Marková, Ivana ; Vachovec, Roman (referee) ; Duchan, David (advisor)
This thesis deals with the processing map multicriteria decision risk analysis on the basis of on available data in accordance with Directive 2007/60/ES and the methodology of the Ministry of Environment of the Czech Republic in 2012 on the selected location in the river Dřevnice at kilometer 2,340 to 16,633.
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The relationships of soil CO2 flux with selected Norway spruce root parameters and sterol content in the soil
Holub, Filip ; Fabiánek, Tomáš ; Večeřová, Kristýna ; Moos, Martin ; Oravec, Michal ; Tříska, Jan ; Marková, I. ; Edwards, Magda ; Cudlín, Pavel
The flow of CO2 from the soil is a very important part of the carbon cycle in an ecosystem. The aim of our work was to determine how roots and rhizospheric fungi contribute to CO2 flux from the soil. Preliminary results from two years of research are presented. The research on how root biomass as well as ergosterol and phytosterol contents in roots and soil affected CO2 flux from the soil was conducted in a 108-year-old Norway spruce (Picea abies (L.) Karst.) forest in the Drahany Highlands during 2010 and 2011. CO2 flow was measured using a LI-8100 portable closed gasometric system (Li-Cor, USA). The dry weight and volume of individual root categories (< 1 mm, 1–2 mm, 2–5 mm, > 5 mm), C and N contents in the roots, as well as ergosterol, β-sitosterol, and campesterol contents in the soil and roots were determined from root-containing soil samples located in the circular measurement chamber. In addition, sterol content was determined in the soil only. Our soil respiration results correspond with the findings of Buchman (2000) who found respiration values between 5–7 μmol CO2 m−2 s−1 in a 111-year-old spruce forest. A significant influence on soil respiration was proven only for sitosterol content in the soil. The relationships among soil CO2 flux, root characteristics, and nitrogen and sterol contents in the roots and soil are discussed.
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