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Patogenesis of aortic stenosis. Posibillity of medical treatment
Štěrbáková, Gabriela ; Linhartová, Kateřina (advisor) ; Rosolová, Hana (referee) ; Staněk, Vladimír (referee) ; Hricák, Vasiľ (referee)
Background: Calcific aortic stenosis is the most frequent and most frequently operated valvular diasease. Currently, there is no known medical treatment to slow the progression of the disease. The aim of our study was first, to assess predictors of the progression of the aortic valve calcification, and second, to assess the association of the progression of aortic stenosis with the bisphosphonate treatment. Methods: Part I - prospective follow-up of consecutive patients with coronary artery disease associated with aortic stenosis (mean transvalvular aortic gradient of 30 mmHg or greater), aortic sclerosis or normal aortic valve were prospectively identified. Clinical, laboratory, echocardographic, angiographic and calcium score evaluation using multidetector computer tomography at baseline, and at the end ofthe study. Predictor of calcification were sought using multivariate regression. Part II - pilot retrospective study of patients with aortic stenosis and two echocardiographies >8 months apart. The patients were divided into those treated with bisphosphonates for osteoporosis and those not treated. We compared the annualized gradient change between the groups and identified predictors of AS progression. Results: Part I 294 patients were prospectively enrolled, with mean follow-up 30±11 months....
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Body - Physicality - Image between Art Education and Drama Education
Linhartová, Kateřina ; Šamšula, Pavel (advisor) ; Slavík, Jan (referee) ; Machková, Eva (referee)
Summary: We work on the assumption that art education as well as the whole educational system should deal with the current issue of "the turn towards body and physicality". Human body, unlike the new rapidly developing media, is the oldest medium that our forefathers used as a means of expression. This may be the cause of the erroneous assumption that we can use this tool without actually learning to use it as we do when working with other visual media. We are attempting to refute this common fallacy. On that account we examine the possibilities of inclusion of a joint concept of art and drama education into regular lessons at primary schools as well as other types of schools. Our aim also is to develop the dialogue between art education and drama education. This work seeks to phrase the reasons and search for the ways of development of physical skills and abilities in art education based on the drama education methodology, while searching for a new concept of work with imagery in drama education in order to achieve its objectives. The researched joint art and drama concept relates to the new concept of the subject of Art and Drama Education taught at the Faculty of Education, Charles University in Prague. Key words: body, physicality, body scheme, body image, image, semiotic body, body representation,...
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The Centre for Demyelinating Illnesses in Prague II. versus the Out patient of Demyelinating Illnesses in České Budějovice ( Multiple sclerosis - the part of my life)
LINHARTOVÁ, Kateřina
My bachelor thesis is devoted to the issue of multiple sclerosis. It is a case of demyelinating disease affecting the central nerve system by inflammatory focuses. It causes nerve channel disorders and nerve fibre destruction, which may result in damage of function followed by disability. Genesis of a multiple sclerosis has not been known yet. It may be generated by a number of factors. The disease affects an individual of younger and medium age, more often women than men. At present the multiple sclerosis is an illness that can be diagnosed as early as at its clinical beginning and the adequate therapy can be started as soon as possible. Although there is no causal treatment yet, modern medical methods represent significant step forward and an increase of the per cent of patients whose central nerve system may not be damaged and permanent disability may not occur. Complex care for the patient with multiple sclerosis is secured by so called MS Centres (Multiple Sclerosis Centres) established and working all over the Czech Republic. The scope of their activity is rather wide: from the diagnostics of the illness, over pharmacological treatment, treatment by a psychologist, socially-legal consultancy and rehabilitation up to the scientifically-research and educational activity.I focused my work on particularly two such establishments {--} The Centre for Demyelinating Diseases in Prague 2 and Outpatient Department of Demyelinating Diseases in České Budějovice. I set up following objectives: the first objective was to map out the provision of services by the two above mentioned establishments. The second objective of my work was to find out the quality of such services involving examinations of patients taking medicines of the first selection and the IVIG (intravenous immunoglobulin), the clinical examination of the patients being monitored, the examination of new patients, the administration of intravenous drip therapy, the services of a psychologist and of a social worker, rehabilitation. I selected a qualitative research for fulfilment of the above mentioned two objectives. The selective pattern involved five clients of the Outpatient Department of Demyelinating Diseases in České Budějovice and seven clients from the Centre for Demyelinating Diseases in Prague 2. The clients were selected by the random systematic selection. The necessary data were collected by method of interview, semi standardized interview technique. The interview was performed with staff of both establishments and with the clients.I would like to contribute by my thesis to increase of the public awareness of the issue of multiple sclerosis, of the services being provided and treatment possibilities. This paper may also be a guide for improvement of services provided to patients suffering from multiple sclerosis. The achieved conclusions and created hypotheses can be used as a basis for further quantitative research of this issue.
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