|
|
The role of vent genes family in early development and brain development
Fabian, Peter ; Kozmík, Zbyněk (advisor) ; Němec, Pavel (referee) ; Balaštík, Martin (referee)
6 III ABSTRACT (ENGLISH) In chordates, the central nervous system (CNS) is derived from the dorsal part of gastrula. Induced dorsal part of the embryo - the neural plate - gives rise to the neural tube or primordial brain. The developing dorsal part of the embryo is shaped by BMP/Smad signaling from the ventral part. Using the basal chordate amphioxus, we show here the conserved evolutionary role BMP/Smad signaling in axial cell fate determination. Pharmalogical inhibition of BMP/Smad signaling induces dorsalization of Branchiostoma floridae (amphioxus) and Oryzias latipes (medaka) embryos and expansion of neural plate markers. We provide evidence for the presence of the positive regulatory loop within the BMP/Smad signaling network of amphioxus. Thus, our data suggest that early emergence of a positive feedback loop within the BMP/Smad signaling network may represent a crucial molecular event in the evolutionary history of the chordate cell fate determination. The dorso-ventral body axis formation is mediated by genes of the vent family, which are the direct targets of BMP/Smad signaling. The function of vent gene family in early development is relatively well known, however, its role in developing CNS is not yet clear. Therefore, we decided to manipulate vox transcription factor, a vent family member....
|
|
|
Unfair terms in consumer contracts in the scope of the Council directive 93/13/EEC
Fabian, Petr ; Dvořák, Jan (advisor) ; Pohl, Tomáš (referee)
- Anglický jazyk Unfair terms in consumer contracts in the scope of the Council Directive 93/13/EEC The protection of consumer against unfair terms in consumer contracts was enacted to our legal order by the transposition of the Council Directive 93/13/EEC, on unfair terms in consumer contract. Until the day of the entry of the Czech Republic to the European Union, there was no legal regulation of the unfair terms in the Czech Republic. Firstly, the aim of this thesis was to evaluate the pros and cons of the Council Directive 93/13/EEC. Consequently this thesis deals with the detailed analysis of the transposition of the directive to the legal order of the Czech Republic. As for the questions de lege ferenda, from this point of view thesis proposes the way of elimination of the lacks of the Council Directive 93/13/EEC and the lacks of the regulation of unfair terms in the valid Czech Civil Code. In the case of the new Civil Code the thesis deals mainly with the questions of conformity of the new Civil Code to the valid Council Directive 93/13/EEC and also deals with the future evolution of the consumer law at the level of the European Union. This thesis also compares the way of transposition of the Council Directive 93/13/EEC in the Czech Republic with the way of transposition of this directive in...
|
|
|
Refaktorizace editoru stromů TrEd
Fabian, Peter ; Žabokrtský, Zdeněk (advisor) ; Kruliš, Martin (referee)
Title: Refactoring tree editor TrEd Author: Peter Fabian Department: Institute of Formal and Applied Linguistics Supervisor: doc. Ing. Zdenek Zabokrtsky, Ph.D., Institute of Formal and Applied Linguistics Abstract: The main goal of the thesis was to refactor tree editor TrEd, improve its modularity, maintainability and make its further development less difficult. Static and dynamic analysis of TrEd have been performed in order to help us find acrid spots in the source code. More than 230 subroutines and data structures have been moved between packages, 50 new packages and a test suite with more than 1,300 tests have been created. A new coding style have been chosen for further development and most severe violations of this standard have been fixed. After the changes done on the source code, it have been analyzed again and the results have been compared with the previous state. Keywords: Tree Editor TrEd, Perl, code refactoring, code analysis
|
|
|
Interactive Data Visualization Tool
Fabian, Peter ; Babka, Vlastimil (referee) ; Parízek, Pavel (advisor)
The goal of the work was to design and implement a tool, which would allow the users to work with a graphical representation of statistic data easily in an interactive manner. The IVP tool supports both the basic adjustments of graphs and advanced modifications, which are either very hard or impossible to achieve in similar tools. However, the key feature of the tool is its extensibility. The particular graph types and the interactive features are implemented as plug-ins and their functionality is provided to the tool's core. The thesis also presents a description of the IVP tool's implementation details, user documentation, an overview of the existing graphing software and its comparison to the IVP tool.
|
|
|
Disposal of Radioactively Contaminated Ion Exchangers by Molten Salt Oxidation – Preliminary Results of the Project.
Pohořelý, Michael ; Šyc, Michal ; Stanovský, Petr ; Stoklasa, J. ; Karásková Nenadálová, L. ; Pražák, P. ; Svoboda, Š. ; Grič, L. ; Fabián, P.
In the contribution, there are summarized significant fuel-energy properties of selected ion exchangers (Purolit A-400 MB OH a Purolit C-100 H) and important properties of suitable melts for process MSO.
Fulltext: content.csg -  PDF
Plný tet: SKMBT_22316060713521 - PDF
|
|
|
MOLECUBES technology application in robotics
Fabián, Petr ; Veverka, Petr (referee) ; Simeonov, Simeon (advisor)
This thesis deals with modular robotics and self-reconfigurable robotic systems. At the beginning are systems defined and classified, the main emphasis is on Molecubes. After that, similar system is designed with a focus on the actual construction of the modules. In conclusion, several sample assemblies was made.
|
|
| |
|
| |
|
| |
guest ::
RSS feed.