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Protein chimistry and massspectromtry in strictural analysis of large proteins
Bezouška, Karel ; Man, Petr ; Pompach, Petr ; Novák, P. ; Havlíček, Vladimír ; Hilgenfeld, R. ; Plíhal, Ondřej ; Sklenář, Jan ; Pišvejcová, Andrea ; Křen, Vladimír
According to the textbook knowledge the use of automated Edman degradation and protein mass spectrometry for the determination of complete primary stricture is limited to small proteins with molecular size less than 10 kDa.
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Dual cytostatic and immunostimulate activity of polymericdrugs
Říhová, Blanka ; Strohalm, Jiří ; Kubáčková, K. ; Jelínková, Markéta ; Rozprimová, L. ; Kovář, Marek ; Šírová, Milada ; Plocová, Daniela ; Mrkvan, Tomáš ; Etrych, Tomáš ; Pokorná, Jindřiška ; Ulbrich, Karel
Classic chemotherapy is toxic for all intensively proliferated cells and tissues.
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Activity of doxorubicin bound to polymeric carrier, containing human IgG was followed in four patients with breast carcinoma
Pokorná, Jindřiška ; Strohalm, Jiří ; Kubáčková, K. ; Jelínková, Markéta ; Rozprimová, L. ; Šírová, Milada ; Plocová, Daniela ; Etrych, Tomáš ; Ulbrich, Karel ; Říhová, Blanka
More than 116 biochemical and immunological parameters wasfollowed in patients with carcinoma.
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Immunological activity of HPMA-doxorubicine copolymer: experiment and clinical study
Šírová, Milada ; Strohalm, Jiří ; Kubáčková, K. ; Rozprimová, L. ; Jelínková, Markéta ; Kovář, Marek ; Mrkvan, Tomáš ; Pokorná, J. ; Renčiuk, Daniel ; Etrych, Tomáš ; Ulbrich, Karel ; Říhová, Blanka
Cytostatics bound to various types of polymers representone of the most promising ways in treatment of cancer.
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