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Multipurpose Town House on Křížová Street, Brno
Doležalová, Iveta ; Mutina, Petr (referee) ; Sochor, Jan (advisor)
The plot is located in Old Brno, in places with rich history, work continues on the analysis from previous semesters. The site has a particularly strong character, supported by well-preserved courtyards with galleries. This arrangement is now a feature space. Closed courts - or semi-private, where they can (to some extent) - the function of housing mixed with other municipal activities and promote the vitality of the house. This work also builds on the solution Mendel Square from previous semester and support the approach taken to assist the courts, courtyards and courtyard for a given location. The block in which the plot is (blank space) is due to the planned puncture Ypsilantiho significant changes will come primarily throughout the eastern part. Together with our Western or 2 vacant lot will be completely free of the block. There is therefore a greater possibility of intervention, links, thinking about this task as a whole. The inspiration for the character building and way of life for a given site, I propose the installation of smaller flats, starter, student, housing for individuals. These apartments will offer common areas, places where people meet. I choose residence as a gallery space houses .... the courts to extend the vertical direction. I propose a system of yards through the entire block, the courts are connected to a central semi-public communication, which is rarely allowed to enter cars. Courts alternate, semi-public courts are the place to galleries and access to the apartment, the living room. Other courts are "green" - private - where there is access only to residents. The courts are quiet-oriented sleeping porches on the kitchen window, so that has galleries with natural living space.
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Functional and structural connectivity of human neocortex in epileptosurgery
Šulc, Vlastimil ; Hořínek, Daniel (advisor) ; Doležalová, Irena (referee) ; Tintěra, Jaroslav (referee)
1 ABSTRACT The presented dissertation deals with prognostic factors influencing a favorable postoperative outcome in patients undergoing surgical treatment of epilepsy and the possibilities of improving the methods used in the localization of epileptogenic lesions. This work is based on the results of four published studies. The first study evaluated the factors influencing the long-term outcomes of epilepsy surgery in MRI-negative (nonlesional) extratemporal lobe epilepsy (nETLE). The aim of the study was to evaluate the benefit of non-invasive diagnostic tests and their relationship with a favorable surgical outcome in a group nETLE patients. Univariate analysis showed that localized interictal epileptiform discharges (IEDs) on the scalp EEG were associated with a favorable surgical outcome. Diagnostic difficulty in this group of patients is highlighted by the fact that, although 9 of 24 patients undergoing surgery had a favorable outcome, and only nine of 85 patients with nETLE achieved such a favorable outcome. The second work evaluated the benefit of SPECT (Single Photon Emission Tomography) statistical processing over traditional subtraction methods in patients with MRI-negative temporal lobe epilepsy (nTLE) and MRI-negative extratemporal epilepsy (nETLE). 49 consecutive patients who underwent...
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The Image of Partisan in Czechoslovak Society 1945-1948
Doležalová, Ivana ; Vojtěchovský, Ondřej (advisor) ; Šustrová, Radka (referee)
The bachelor thesis (work) The Image of Partisan in Czechoslovak Society 1945 - 1948 based on study of contemporary press shows the way the partisan movement was presented in Czechoslovak public space. The work introduces the development of the media image of partisan in the press during the early post-war years. It describes, when the type of guerrilla fighter as a representative of the antifascist resistance occured, who this presentation Czechslovak resistance advocated most, and if it was at the expense of other forms of resistance activities. The focus of the work is the analysis of main source of the problems of formating post-war media image of the partisan movement - weekly Partisan, in the years 1946, 1947 and early 1948. The qualitative analysis enabeled putting down the media image of partisan in weekly Partisan, its transformation through the time, and simultaneously the confrontation with some other post-war Czechoslovak periodicals. The contribution of this work is in the fact that it complements previous studies on the topic of the partisan movement of view of post-war contemporary press.
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Political trials in Czechoslovakia - The Case "Zpěvačka"
Doležalová, Ivana ; Županič, Jan (advisor) ; Lánský, Ondřej (referee)
This Master's thesis will look at the Political trials in Czechoslovakia - The case of "Zpěvačka", it will focus on one of the many politically motivated processes that took place in Czechoslovakia during the communist regime, i.e. 1948-1989. The focus of this paper is to analyse the key archival sources, which is now an investigation by the State Security in the case of "Zpěvačka", now stored in the Archive of Security Forces. The trial of the anti-state oriented group of people around Radana Melicharová who were accused of collaborating with foreign intelligence services took place in the spring of 1957. This shows that even the so-called foundation period of the communist regime, the Communist Party of Czechoslovakia continued to implement political processes to control the opposition. This thesis brings the main characters of the process Radana Melicharová et al., describes their illegal activities and analyses the motives of each participants on illegal activities. And also discusses about the main trial itself at the Regional Court in Prague, subsequent appeal trials and the efforts to rehabilitate convicts. Contribution of the work lies in the fact that it complements many previously published scientific studies on the topic of the political process and less known and studied process with a...
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Optimizing of epilepsy surgery in paediatric patients
Bělohlávková, Anežka ; Kršek, Pavel (advisor) ; Doležalová, Irena (referee) ; Vojtěch, Zdeněk (referee)
Optimizing of Epilepsy Surgery in Paediatric Patients Abstract Epilepsy surgery represents an effective treatment of intractable focal epilepsy. The presented work aims to describe the state of the art and enhance diagnostic and therapeutic algorithm in paediatric patients. The ultimate goal is to improve the outcome of surgeries. The work depicts the evolution of the paediatric epilepsy surgery program in Motol Epilepsy Center over the course of years 2000-2017. Complexity of patients (younger age, epileptogenic zone in proximity of eloquent cortex, multifocal MRI findings) and surgeries (hemispherotomy) alike increased over time. However, the outcomes in terms of postoperative seizure-freedom and complications remained stable. Cognitive abilities of patients improved by 9.1 IQ/DQ points one year after surgery. Patients with preexisting intellectual deficit reached the most significant increase. We developed a novel paradigm of intraoperative cortical electrical stimulation mapping. Furthermore, we introduced a technique employing visual detection of SEEG electrodes during the surgery. These procedures aim to achieve a complete resection while avoiding complications. We developed and standardized Czech versions of questionnaires IPES a QOLIE-AD-48 assessing quality of life in children with epilepsy. We...
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Functional and structural connectivity of human neocortex in epileptosurgery
Šulc, Vlastimil ; Hořínek, Daniel (advisor) ; Doležalová, Irena (referee) ; Tintěra, Jaroslav (referee)
1 ABSTRACT The presented dissertation deals with prognostic factors influencing a favorable postoperative outcome in patients undergoing surgical treatment of epilepsy and the possibilities of improving the methods used in the localization of epileptogenic lesions. This work is based on the results of four published studies. The first study evaluated the factors influencing the long-term outcomes of epilepsy surgery in MRI-negative (nonlesional) extratemporal lobe epilepsy (nETLE). The aim of the study was to evaluate the benefit of non-invasive diagnostic tests and their relationship with a favorable surgical outcome in a group nETLE patients. Univariate analysis showed that localized interictal epileptiform discharges (IEDs) on the scalp EEG were associated with a favorable surgical outcome. Diagnostic difficulty in this group of patients is highlighted by the fact that, although 9 of 24 patients undergoing surgery had a favorable outcome, and only nine of 85 patients with nETLE achieved such a favorable outcome. The second work evaluated the benefit of SPECT (Single Photon Emission Tomography) statistical processing over traditional subtraction methods in patients with MRI-negative temporal lobe epilepsy (nTLE) and MRI-negative extratemporal epilepsy (nETLE). 49 consecutive patients who underwent...
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A practical value of different intraoperative electrophysiological methods in pediatric epilepsy surgery patients
Leško, Róbert ; Kršek, Pavel (advisor) ; Netuka, David (referee) ; Doležalová, Irena (referee)
Epilepsy, as the most common chronic neurological disease, affects a significant part of population (0.5-1%). Drug resistant epilepsy has a significant negative effect on the quality of life, psychiatric comorbidities, neurocognitive performance and the risk of SUDEP in children. Therefore, resective epilepsy surgery, the only curative treatment of this condition, can fundamentally reverse this unfavorable prognosis. An inevitable prerequisite for a good postoperative result is complete removal of the epileptogenic zone (EC) and preservation of eloquent areas (EC). At present, even with improving and new preoperative non-invasive methods, we don't have an exclusive diagnostic method for theirs delineation. The aim of this PhD study is to assess benefit of individual intraoperative electrophysiological (iEF) methods in pediatric patients with focal intractable epilepsy. The first study evaluates the importance of intraoperative electrocorticography (iECoG) in the localization of EZ. The study proved that iECoG serves as a reliable tool to guide surgical resection and may predict results of epilepsy surgery. iECoG-based modification of surgical plan is not associated with increased risk of significant complications. The second presented study analyzed the contribution of intraoperative electrical...
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Political trials in Czechoslovakia - The Case "Zpěvačka"
Doležalová, Ivana ; Županič, Jan (advisor) ; Lánský, Ondřej (referee)
This Master's thesis will look at the Political trials in Czechoslovakia - The case of "Zpěvačka", it will focus on one of the many politically motivated processes that took place in Czechoslovakia during the communist regime, i.e. 1948-1989. The focus of this paper is to analyse the key archival sources, which is now an investigation by the State Security in the case of "Zpěvačka", now stored in the Archive of Security Forces. The trial of the anti-state oriented group of people around Radana Melicharová who were accused of collaborating with foreign intelligence services took place in the spring of 1957. This shows that even the so-called foundation period of the communist regime, the Communist Party of Czechoslovakia continued to implement political processes to control the opposition. This thesis brings the main characters of the process Radana Melicharová et al., describes their illegal activities and analyses the motives of each participants on illegal activities. And also discusses about the main trial itself at the Regional Court in Prague, subsequent appeal trials and the efforts to rehabilitate convicts. Contribution of the work lies in the fact that it complements many previously published scientific studies on the topic of the political process and less known and studied process with a...
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