Original title: Activity of antimicrobial peptides from the venom of hymenoptera against Candida albicans biofilms
Authors: Putnová, Helena ; Fučík, Vladimír ; Monincová, Lenka ; Čeřovský, Václav ; Slaninová, Jiřina
Document type: Papers
Conference/Event: Biologically Active Peptides /12./, Praha (CZ), 2011-04-27 / 2011-04-29
Year: 2011
Language: eng
Abstract: Biofilms are nowadays a serious problem especially with immunosuppressed patients. These highly resistant agglomerations are formed by cells which are firmly adhered to the surface. In this work, the effect of antimicrobial peptides isolated from venom reservoirs of wild bees were tested against Candida albicans biofilms. The results show that some synthetic analogues exhibit potency to kill quickly the yeast biofilm cells. On the contrary, some analogues active against planktonic cells are only little active or inactive against biofilms.
Keywords: antifungal activity; antimicrobial peptides; biofilm; XTT assay
Project no.: CEZ:AV0Z40550506 (CEP), GA203/08/0536 (CEP)
Funding provider: GA ČR
Host item entry: Biologically Active Peptides. 12th Conference, ISBN 978-80-86241-44-9

Institution: Institute of Organic Chemistry and Biochemistry AS ČR (web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0204348

Permalink: http://www.nusl.cz/ntk/nusl-81019


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Research > Institutes ASCR > Institute of Organic Chemistry and Biochemistry
Conference materials > Papers