Original title: Regulace replikace DNA pomocí ubikvitin proteazomového systému
Translated title: Control of DNA replication mediated by the ubiquitin-proteasome system
Authors: Kolumpek, Lukáš ; Čermák, Lukáš (advisor) ; Polášek-Sedláčková, Hana (referee)
Document type: Bachelor's theses
Year: 2024
Language: eng
Abstract: [eng] [cze]
The ubiquitin-proteasome system is an essential cellular instrument that provides timely degradation of specific protein substrates. This thesis examines its role in the regulation of DNA replication with emphasis on human cells, while thoroughly exploring DNA replication, with respect to its position in the cell cycle, and the ubiquitin-proteasome system. Ubikvitin-proteazomový systém je důležitý buněčný systém, který zajišťuje včasnou degradaci specifických proteinů. Tato práce se zaměřuje na jeho roli při regulaci replikace DNA s důrazem na lidské buňky a detailní výklad replikace DNA a ubikvitin-proteazomového systému.
Keywords: cell cycle; DNA replication; proteasome; Ubiquitin; ubiquitin ligase; buněčný cyklus; DNA replikace; proteazom; Ubikvitin; ubikvitin ligáza

Institution: Charles University Faculties (theses) (web)
Document availability information: Available in the Charles University Digital Repository.
Original record: http://hdl.handle.net/20.500.11956/190070

Permalink: http://www.nusl.cz/ntk/nusl-620870


The record appears in these collections:
Universities and colleges > Public universities > Charles University > Charles University Faculties (theses)
Academic theses (ETDs) > Bachelor's theses