Název:
A New Approach to Determining the Drug Guaifenesin Using Voltammetric and Flow Injection Analysis
Autoři:
Kelíšková, P. ; Matvieiev, O. ; Sokolová, Romana ; Janíková, L. ; Behúl, M. ; Šelešovská, R. Typ dokumentu: Příspěvky z konference Konference/Akce: Modern Electrochemical Methods /43./, Jetřichovice (CZ), 20240520
Rok:
2024
Jazyk:
eng
Abstrakt: This study presents a new method for detecting guaifenesin (GFE) in pharmaceutical samples. We employed screen-printed sensors with a boron-doped diamond electrode (BDDE) to develop and validate both voltammetric and flow amperometric methods. These approaches were effectively used to analyze model solutions, pharmaceutical preparations, and serum samples spiked with GFE, producing accurate results comparable to those obtained with HPLC/DAD analysis. The developed methods provide straightforward, sensitive, and selective means for determining GFE in various sample matrices, underscoring the potential of SP/BDDE in electrochemical analysis.
Klíčová slova:
boron-doped diamond electrode; guaifenesin; screen-printed sensor Zdrojový dokument: Proceedings of the International Conference. 43rd Modern Electrochemical Methods, ISBN 978-80-908947-1-6
Instituce: Ústav fyzikální chemie J. Heyrovského AV ČR
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Informace o dostupnosti dokumentu:
Dokument je dostupný na vyžádání prostřednictvím repozitáře Akademie věd. Původní záznam: https://hdl.handle.net/11104/0353834