Original title: A New Approach to Determining the Drug Guaifenesin Using Voltammetric and Flow Injection Analysis
Authors: Kelíšková, P. ; Matvieiev, O. ; Sokolová, Romana ; Janíková, L. ; Behúl, M. ; Šelešovská, R.
Document type: Papers
Conference/Event: Modern Electrochemical Methods /43./, Jetřichovice (CZ), 20240520
Year: 2024
Language: eng
Abstract: This study presents a new method for detecting guaifenesin (GFE) in pharmaceutical samples. We employed screen-printed sensors with a boron-doped diamond electrode (BDDE) to develop and validate both voltammetric and flow amperometric methods. These approaches were effectively used to analyze model solutions, pharmaceutical preparations, and serum samples spiked with GFE, producing accurate results comparable to those obtained with HPLC/DAD analysis. The developed methods provide straightforward, sensitive, and selective means for determining GFE in various sample matrices, underscoring the potential of SP/BDDE in electrochemical analysis.
Keywords: boron-doped diamond electrode; guaifenesin; screen-printed sensor
Host item entry: Proceedings of the International Conference. 43rd Modern Electrochemical Methods, ISBN 978-80-908947-1-6

Institution: J. Heyrovsky Institute of Physical Chemistry AS ČR (web)
Document availability information: Fulltext is available on demand via the digital repository of the Academy of Sciences.
Original record: https://hdl.handle.net/11104/0353834

Permalink: http://www.nusl.cz/ntk/nusl-615866


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Research > Institutes ASCR > J. Heyrovsky Institute of Physical Chemistry
Conference materials > Papers