Original title:
Synthesis of novel C-(o-carboranyl)-2-deoxy-d-ribose conjugates
Authors:
Šnajdr, I. ; Janoušek, Z. ; Kotora, Martin Document type: Papers Conference/Event: Chemistry of Nucleic Acid Components /15./, Český Krumlov (CZ), 2011-06-05 / 2011-06-10
Year:
2011
Language:
eng Abstract:
Carboranes are clusters consisting of carbon, boron and hydrogen and because they have high percent of boron by weight, they are used as 10B carriers for cancer therapy (boron neutron capture therapy, BNCT). Therefore a series of novel o-carboranyl-deoxyribose conjugates as water soluble substances has been synthesized.
Keywords:
alkynes; carboranes; nucleosides Project no.: CEZ:AV0Z40550506 (CEP) Host item entry: Chemistry of Nucleic Acid Components. 15th Symposium, ISBN 978-80-86241-37-1
Institution: Institute of Organic Chemistry and Biochemistry AS ČR
(web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences. Original record: http://hdl.handle.net/11104/0198883