Original title:
Synthesis of nucleotides bearing oligopyridine ligands and their incorporation into DNA
Authors:
Kalachová, Lubica ; Hocek, Michal Document type: Papers Conference/Event: Chemistry of Nucleic Acid Components /15./, Český Krumlov (CZ), 2011-06-05 / 2011-06-10
Year:
2011
Language:
eng Abstract:
The synthesis of 7-deaza-dATPs and dCTPs bearing bipyridine or terpyridine ligands via acetylene tethers was accomplished through Pd-catalyzed cross-coupling reactions. Different DNA polymerases were used for their incorporation into DNA.
Keywords:
bipyridine; DNA; nucleotides; terpyridine Project no.: CEZ:AV0Z40550506 (CEP), LC512 (CEP), GA203/09/0317 (CEP) Funding provider: GA MŠk, GA ČR Host item entry: Chemistry of Nucleic Acid Components. 15th Symposium, ISBN 978-80-86241-37-1
Institution: Institute of Organic Chemistry and Biochemistry AS ČR
(web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences. Original record: http://hdl.handle.net/11104/0198860