Original title: Analýza vybraných nutraceutik pomocí kapalinové chromatografie
Translated title: Analysis of selected nutraceuticals by liquid chromatography
Authors: Ibrahim, Laureen Reda Youssef ; Jenčo, Jaroslav (advisor) ; Opletal, Lubomír (referee)
Document type: Master’s theses
Year: 2023
Language: eng
Abstract: 39 ABSTRACT Charles University, Faculty of Pharmacy in Hradec Králové Department: Department of Pharmacognosy and Pharmaceutical Botany Candidate: Laureen Reda Youssef Ibrahim Supervisor: RNDr. Jaroslav Jenčo, Ph.D. Title of dissertation thesis: Analysis of selected nutraceuticals by liquid chromatography The extract obtained pellets of Humulus Lupulus L. var Columbus was subjected to a phytochemical study and isolation of its bitter acid constituents. The summary extract was separated into individual fractions by liquid-liquid extraction. After performing HPTLC, GC-MS, and LC-MS analysis, the fraction HL-Hex B was selected and purified further by preparative chromatography. A monocomponent pale yellow solid substance of lupulone was obtained after the final preparative separation. Based on instrumental analysis by reversed phase HPLC with core-shell particles, the analyte was compared to the extract of dietary supplement HopsVital where the presence of bitter acids in the supplement was shown. Key words: nutraceuticals, high performance liquid chromatography, sample preparation, modern stationary phases
Keywords: high performance liquid chromatography; modern stationary phases; nutraceuticals; sample preparation; moderní stqacionární fáze; nutraceutika; vysokoúčinná kapalinová chromatografie; úprava vzorek

Institution: Charles University Faculties (theses) (web)
Document availability information: Available in the Charles University Digital Repository.
Original record: http://hdl.handle.net/20.500.11956/181141

Permalink: http://www.nusl.cz/ntk/nusl-527815


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Academic theses (ETDs) > Master’s theses