Supramolekulární komplexy oxoporfyrinogenů s organickými molekulami

Březina, Václav

Title: Supramolecular complexes of oxoporphyrinogens with organic molecules Author: Václav Březina Department: Department of Macromolecular Physics Supervisor: doc. RNDr. Lenka Hanyková, Dr., Department of Macromolecular Physics Abstract: Oxoporphyrinogens are flat macrocyclic molecules possessing binding and protonation sites, and capable of light absorption in the visible region. These properties are prerequisites for a colori- metric molecular sensor, i.e. a specific detector of other molecules in the sample. In this work, we studied chromic properties of three oxoporphyrinogens, OxP and its partially (Bz2OxP) and fully (Bz4OxP) N-benzylated derivatives. Their colorimetric response to organic acids is caused by protonation and subsequent formation of supramolecular host-guest complex. We have shown that colorimetric sensitivity is highest for OxP and gradually weakens for Bz2OxP and Bz4OxP since the N-benzylation blocks the central binding sites, decreasing binding affinity of the ox- oporphyrinogens. Furthermore, solvatochromic response of the oxoporphyrinogens to varying solvent polarity showed similar sensitivity decrease in Bz2OxP and Bz4OxP. The chromic and binding properties were studied by UV/vis and NMR spectroscopy, host-guest binding models were applied to describe the formation of...

host :: přihlásit Digitální repozitář
		Hledej		Nový záznam		Nápověda		O repozitáři