Original title: Vývoj, optimalizace a validace analytické metody na stanovení kyseliny chikorové a dalších derivátů kyseliny kávové pomocí LC/MS
Authors: PAZDERKOVÁ, Nela
Document type: Bachelor's theses
Year: 2021
Language: cze
Abstract: This thesis deals with the development, optimization, and validation of an analytical method for the determination of chicoric acid and other caffeic acid derivates using LC/MS. First, the development and optimization of the analytical method was conducted. The following parameters were selected for the optimization: mobile phase composition and flow rate injection volume capillary temperature, voltage S-lens and F-lens voltage, ion injection time, product ion selection, and collision energy. Then, the analytical method was successfully validated and tested for quantitative analysis in a range of Echinacea food matrixes - tea, tablet, and tincture.
Keywords: antioxidants; caffeic acid; caftaric acid; Chicoric acid; chlorogenic acid; cynarin; echinacosid; liquid chromatography; mass spectrometry; optimization; validation.; antioxidanty; cynarin; echinakosid; hmotnostní spektrometrie; kapalinová chromatografie; Kyselina chikorová; kyselina chlorogenová; kyselina kaftarová; kyselina kávová; optimalizace; validace.
Citation: PAZDERKOVÁ, Nela. Vývoj, optimalizace a validace analytické metody na stanovení kyseliny chikorové a dalších derivátů kyseliny kávové pomocí LC/MS. České Budějovice, 2021. bakalářská práce (Bc.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta

Institution: University of South Bohemia in České Budějovice (web)
Document availability information: Fulltext is available in the Digital Repository of University of South Bohemia.
Original record: http://www.jcu.cz/vskp/63720

Permalink: http://www.nusl.cz/ntk/nusl-517896


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Universities and colleges > Public universities > University of South Bohemia in České Budějovice
Academic theses (ETDs) > Bachelor's theses