Název:
Algorithmic prediction of functional changes within protein sequence
Autoři:
TOLAR, Nikolas Typ dokumentu: Bakalářské práce
Rok:
2021
Jazyk:
eng
Abstrakt: The Following thesis provides a theoretical background to the biology of a naked mole-rat (Heterocephalus glaber), highlighting its unique characteristics that could potentially be explained by altered epigenetic mechanisms. In order to identify potentially functional evolutionarily changed sites in epigenetic modifiers, we developed a novel approach to protein scanning through the utilization of multiple-sequence alignments and protein annotations available in public databases. The key result is computer software and analysis of the obtained results, identifying candidate proteins with potentially altered functions.
Klíčová slova:
bioinformatics; epigenetics; functional changes; multiple-sequence analysis; naked mole-rats; proteins; Python; transcription factors Citace: TOLAR, Nikolas. Algorithmic prediction of functional changes within protein sequence. České Budějovice, 2021. bakalářská práce (Bc.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta
Instituce: Jihočeská univerzita v Českých Budějovicích
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Informace o dostupnosti dokumentu:
Plný text je dostupný v digitálním repozitáři JČU. Původní záznam: http://www.jcu.cz/vskp/63521