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Original title:
The use of Boron Doped Diamond Electrode for Determination of 5-hydroxyindoleacetic Acid
Authors: Hrdlička, Vojtěch ; Navrátil, Tomáš
Document type: Papers
Conference/Event: Moderní Elektrochemické Metody /40./, Jetřichovice (CZ), 20211108
Year: 2021
Language: eng
Abstract: A new method for voltammetric determination of clinical biomarker 5-hydroxyindoleacetic\nacid (HIAA) at the boron-doped diamond electrode (BDDE) was developed. Anodically and\ncathodically pretreated BDDEs were tested in the pH ranges from 1 to 12, pre-treatment at\n+2.0V/60 s, and pH 3 was found to be the optimum.\nThe optimum square wave voltammetry (SWV) parameters were: f = 12 Hz, amplitude 60\nmV, and potential step 4 mV. SWV concentration dependency was constructed in the range\nfrom 0.1 to 100 μmol L−1, limits of determination and detection were 0.3 and 0.1 μmol L−1,\nrespectively. HIAA oxidation electrode process at BDDE was diffusion-controlled, as\nuncovered by cyclic voltammetry. Interestingly, HIAA peak potential was constant in various\nranges of pH, indicating a non-Nernstian behavior at the BDDE, in contrast to a previously\npublished electrooxidation mechanism consisting of a coupled H+/e− transfer.
Keywords: 5-hydroxyindoleacetic acid; boron-doped diamond electrode; square wave voltammetry
Project no.: GA20-01589S (CEP)
Funding provider: GA ČR
Host item entry: Sborník přednášek mezinárodní odborné konference XL. Moderní Elektrochemické Metody, ISBN 978-80-905221-8-3
Institution: J. Heyrovsky Institute of Physical Chemistry AS ČR (web)
Document availability information: Fulltext is available on demand via the digital repository of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0325181
Permalink: http://www.nusl.cz/ntk/nusl-508268
The record appears in these collections:
Research > Institutes ASCR > J. Heyrovsky Institute of Physical Chemistry
Conference materials > Papers
Authors: Hrdlička, Vojtěch ; Navrátil, Tomáš
Document type: Papers
Conference/Event: Moderní Elektrochemické Metody /40./, Jetřichovice (CZ), 20211108
Year: 2021
Language: eng
Abstract: A new method for voltammetric determination of clinical biomarker 5-hydroxyindoleacetic\nacid (HIAA) at the boron-doped diamond electrode (BDDE) was developed. Anodically and\ncathodically pretreated BDDEs were tested in the pH ranges from 1 to 12, pre-treatment at\n+2.0V/60 s, and pH 3 was found to be the optimum.\nThe optimum square wave voltammetry (SWV) parameters were: f = 12 Hz, amplitude 60\nmV, and potential step 4 mV. SWV concentration dependency was constructed in the range\nfrom 0.1 to 100 μmol L−1, limits of determination and detection were 0.3 and 0.1 μmol L−1,\nrespectively. HIAA oxidation electrode process at BDDE was diffusion-controlled, as\nuncovered by cyclic voltammetry. Interestingly, HIAA peak potential was constant in various\nranges of pH, indicating a non-Nernstian behavior at the BDDE, in contrast to a previously\npublished electrooxidation mechanism consisting of a coupled H+/e− transfer.
Keywords: 5-hydroxyindoleacetic acid; boron-doped diamond electrode; square wave voltammetry
Project no.: GA20-01589S (CEP)
Funding provider: GA ČR
Host item entry: Sborník přednášek mezinárodní odborné konference XL. Moderní Elektrochemické Metody, ISBN 978-80-905221-8-3
Institution: J. Heyrovsky Institute of Physical Chemistry AS ČR (web)
Document availability information: Fulltext is available on demand via the digital repository of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0325181
Permalink: http://www.nusl.cz/ntk/nusl-508268
The record appears in these collections:
Research > Institutes ASCR > J. Heyrovsky Institute of Physical Chemistry
Conference materials > Papers
Record created 2022-09-28, last modified 2024-04-15