Original title:
Computer assisted development of a pneumatic electrospray nebulizer
Authors:
Járvás, G. ; Szigeti, M. ; Grym, Jakub ; Foret, František ; Guttman, A. Document type: Papers Conference/Event: CECE 2014. International Interdisciplinary Meeting on Bioanalysis /11./, Brno (CZ), 2014-10-20 / 2014-10-22
Year:
2014
Language:
eng Abstract:
In this study we demonstrate how computer simulations can assist the development of a novel microfabricated pneumatic electrospray nebulizer. The microdevice under consideration is designed for electrospray mass spectrometry interfacing without the need to fabricate an electrospray needle. This new interfacing strategy requires comprehensive evaluation of the differently designed chip layouts. The flow evaluation was supported by computational fluid dynamics simulations. It was proved with experimental validation of the simulation results that the developed models were practical tools for the numerical investigation of the separations-ESI-MS coupling.
Keywords:
electrospray mass spectrometry; microfabricated ESI-MS; pneumatic electrospray nebulizer Host item entry: CECE 2014. 11th International Interdisciplinary Meeting on Bioanalysis, ISBN 978-80-904959-2-0