Original title: Izolace alkaloidů z prameničky obecné (Fontinalis antipyretica Hedw.)
Translated title: Alkaloid isolation from Fontinalis antipyretica Hedw.
Authors: Malá, Marie ; Martin, Jan (advisor) ; Kašparová, Marie (referee)
Document type: Master’s theses
Year: 2012
Language: cze
Abstract: [cze] [eng]
Marie Malá, Izolace alkaloidů z prameničky obecné (Fontinalis antipyretica), diplomová práce, Univerzita Karlova v Praze, Farmaceutická fakulta v Hradci Králové, 2012, 55 stran. Diplomová práce s názvem "Izolace alkaloidů z prameničky obecné" se zabývá stanovením obsahu a izolací alkaloidních látek ve výše zmíněném mechu. Rostlinný materiál sesbíraný na lokalitách v České republice byl extrahován methanolem a extrakt sloužil pro izolaci alkaloidů. Podařilo se vyizolovat 2,4 mg β-karbolínového alkaloidu. Při HPLC analýzách ve srovnání se standardem harmalolu vykazoval alkaloid stejné vlastnosti (retenční čas, spektrum). Pomocí H NMR analýzy bylo zjištěno, že se nejedná o harmalol, ale jiný β-karbolínový alkaloid. Marie Malá, Isolation of alkaloids from Fontinalis antipyretica, thesis, Charles University in Prague, Faculty Of Pharmacy in Hradec Králové, 2012, 55 pages. The thesis Isolation of alkaloids from Fontinalis antipyretica, deals with quantification and isolation of substances of alkaloid character from above mentioned moss. The plant material collected in different localities in Czech Republic was extracted with methanol. The extract was subesquently used for isolation of alkaloids by HPLC method. The obtained amount of β-Carboline alkaloid was 2,4mg. The results of HPLC analysis (retention time, spectrum) of this sample were compared to harmalol standard and found the same. Finally the H NMR analysis proved, that the substance obtained by this experiment is not harmalol, but someother β-Carboline alkaloid.
Keywords: Alkaliod; Fontinalis antipyretica Hedw; Alkaloid; pramenička obecná

Institution: Charles University Faculties (theses) (web)
Document availability information: Available in the Charles University Digital Repository.
Original record: http://hdl.handle.net/20.500.11956/43997

Permalink: http://www.nusl.cz/ntk/nusl-501253


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Universities and colleges > Public universities > Charles University > Charles University Faculties (theses)
Academic theses (ETDs) > Master’s theses