Název: Regulace nových cytokinů při autoimunních revmatických onemocněních
Překlad názvu: Regulation of Novel cytokines in Autoimmune Rheumatic Diseases
Autoři: Yadollahi, Benjamin ; Šenolt, Ladislav (vedoucí práce) ; Krulová, Magdaléna (oponent)
Typ dokumentu: Diplomové práce
Rok: 2012
Jazyk: eng
Abstrakt: [eng] [cze]
A large number of cytokines are expressed in the feet and hands joints of patients with Rheumatoid arthritis. It is necessary to study the new cytokines which may help in prognosis and diagnosis of this autoimmune disease. Omentin1 and Interleukin 20 are the new cytokines and their expressions may have a role in the expression of proinflammatory cytokines; IL-1, IL-6 and TNF, in different cell tissues such as synovial fibroblasts, chondrocytes, peripheral blood mononuclear cells and, sera. It is conceivable that these biomarkers may be used in biological therapies. Abstruct A large number of cytokines are expressed in the feet and hands joints of patients with Rheumatoid arthritis. It is necessary to study the new cytokines which may help in prognosis and diagnosis of this autoimmune disease. Omentin1 and Interleukin 20 are the new cytokines and their expressions may have a role in the expression of proinflammatory cytokines; IL-1, IL-6 and TNFα, in different cell tissues such as synovial fibroblasts, chondrocytes, peripheral blood mononuclear cells and, sera. It is conceivable that these biomarkers may be used in biological therapies.
Klíčová slova: Cytokines,proinflammatory; Interleukin 21; Interleukin 6; Interleukin1; Omentin1; Rheumatoid diseases; Tumor necorsis factor- joint damages

Instituce: Fakulty UK (VŠKP) (web)
Informace o dostupnosti dokumentu: Dostupné v digitálním repozitáři UK.
Původní záznam: http://hdl.handle.net/20.500.11956/42394

Trvalý odkaz NUŠL: http://www.nusl.cz/ntk/nusl-500973


Záznam je zařazen do těchto sbírek:
Školství > Veřejné vysoké školy > Univerzita Karlova > Fakulty UK (VŠKP)
Vysokoškolské kvalifikační práce > Diplomové práce