Kostní augmentační materiály, hodnocení osteointegrace implantátů

Moztarzadeh, Omid

Bone Augmentation Materials Evaluation of Implant Osteointegration This dissertation thesis contains a description and results of six constituent studies. The first study was performed in order to investigate the most common indications for the use of three bone augmentation materials, Biogen, Cerasorb and Bioresorb. The most common indications identified were based on statistical data collected from patients treated at the Maxillofacial Surgery Department, Faculty Hospital in Pilsen, during 2003-2007. The second experiment was performed in vivo. We evaluated the possible osteoinduction potential and osteogenic activities of two different bone augmentation materials (Cerasorb, Biogen) by examining whether ectopic bone formation could be induced when implanted subcutaneously into the extremities of our test subjects (pigs). The results obtained, highlight the potential future use, of augmentation materials in creation of hard tissues, in areas where soft tissues are normally present. The third experiment was performed in order to evaluate the efficiency of Cerasorb bone augmentation material in bone healing. Cerasorb was applied into an artificial hole in the extremities of the test subjects and based on careful analysis of the radiographic and histological images, we found that Cerasorb gradually resorbed...

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