Posttraumatická stresová porucha a její biomarkery

Shalkin, Ilia

Post-traumatic stress disorder (PTSD) originally referred to conditions observed among military people. It was first widely accepted as a diagnosis during the First World War. As a result, PTSD was no longer attributed exclusively to the military environment and, at the moment, there are a large number of studies that relate to civilians who developed trauma as a result of a terrorist attack, rape, the death of a loved one, natural and man-made disasters. Severe trauma can affect everyone, and most people manage to cope with stress and continue to live their everyday lives. However, some people may develop PTSD. A person diagnosed with PTSD may have sleep disorders and nightmares, increased irritability, feel guilty and look for the cause of problems in themselves, and may not experience positive emotions. Symptoms of PTSD have a destructive effect on the patient himself and affect loved ones, leading to a break in social ties and loss of work. PTSD is a complex disease affecting various regulatory systems of the body, but despite many studies, the aetiology of PTSD development is not clear today. This fact limits scientists in developing a treatment for PTSD. One of the ways to develop research on the treatment of PTSD uses preclinical and clinical methods to track biomarkers associated with...

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