Original title: Monitoring The Parameters Of Cells Migrating In Pseudo-3d Extracellular Matrix
Authors: Zumberg, Inna
Document type: Papers
Language: cze
Publisher: Vysoké učení technické v Brně, Fakulta elektrotechniky a komunikačních technologií
Abstract: Cell migration plays an essential role in a number of biological processes, such as embryogenesis,the immune response, wound healing and inflammation. Most research regarding cellmigration is based on experiments using two-dimensional (2D) cell cultures, and the detailed molecularand biophysical mechanisms of these processes are already well known. However, muchless is known about cell behaviour in the three-dimensional (3D) environment of living tissues.Pseudo-three-dimensional (pseudo-3D) cell cultures bridge the gap between 2D and 3D geometriesand combine their advantages. This review presents the quantitative evaluation of human mesenchymalstem cells (hMSCs) migration parameters in pseudo-3D artificial extracellular matrix(ECM) of various compositions.
Keywords: Collagen; Confocal microscopy; Extracellular matrix; hMSCs; Pseudo-3D
Host item entry: Proceedings I of the 27st Conference STUDENT EEICT 2021: General papers, ISBN 978-80-214-5942-7

Institution: Brno University of Technology (web)
Document availability information: Fulltext is available in the Brno University of Technology Digital Library.
Original record: http://hdl.handle.net/11012/200769

Permalink: http://www.nusl.cz/ntk/nusl-447814


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