Název:
Degradation of mechanical properties of magnesium alloy
Autoři:
Sedláček, R. ; Suchý, Tomáš ; Padovec, Z. Typ dokumentu: Příspěvky z konference Konference/Akce: International Scientific Conference on Experimental Stress Analysis /57./ EAN 2019, Luhačovice (CZ), 20190603
Rok:
2019
Jazyk:
eng
Abstrakt: In this study, biodegradation behaviour of WE43 magnesium alloy have been studied and compared during exposure to three different media commonly used to simulate the conditions of human body environment. Magnesium alloys emerged as a new class of bioresorbable implant materials. Their applications reduce certain risks associated with conventional permanent implants. Biodegradation behaviour of the WE43 magnesium alloy was observed under Dulbecco Modified Eagle Medium (DMEM, Sigma Aldrich) supplemented with 5 % fetal bovine serum and gentamicin antibiotic as standard. The samples were stored in the medium at 37 degrees C and in a 5 % CO2 atmosphere. The second type of medium was Hank's Salt Balanced Solution (HBSS, Sigma Aldrich), which simulates the inorganic composition of blood plasma. HBSS was tempered at 37 degrees C. The last solution was an acidic solution of HCl + NaCl (pH2) with pH similar to 2 (0.01M HCl and 0.14M NaCl) tempered at 37 degrees C. The acidic type of solution was used to simulate a local acidic environment associated with osteoclast activity during bone remodelling. Changes in the mechanical properties of the samples during exposure to simulated body conditions were observed.
Klíčová slova:
Bioabsorbable metals; Biodegradation; Implant; Magnesium Zdrojový dokument: Experimental Stress Analysis (EAN 2019), ISBN 978-802145766-9 Poznámka: Související webová stránka: https://www.researchgate.net/publication/333679700_Degradation_of_mechanical_properties_of_magnesium_alloy
Instituce: Ústav struktury a mechaniky hornin AV ČR
(web)
Informace o dostupnosti dokumentu:
Dokument je dostupný v příslušném ústavu Akademie věd ČR. Původní záznam: http://hdl.handle.net/11104/0313343