Název:
Mechanical and structural properties of collagen nanofribrous layers under simulated body conditions
Autoři:
Říhová, J. ; Suchý, Tomáš ; Vištejnová, L. ; Horný, L. ; Šupová, Monika Typ dokumentu: Příspěvky z konference Konference/Akce: Youth Symposium on Experimental Solid Mechanics /17./, Telč (CZ), 20190606
Rok:
2019
Jazyk:
eng
Abstrakt: The theme of this paper is the analysis of mechanical and structural properties of nanofibrous COL under simulated body conditions and in the presence of osteoblasts and dermal fibroblasts. COL were prepared by electrostatic spinning of 8 wt% collagen type I dispersion with 8 wt% (to COL) of PEG in phosphate buffer/ethanol solution (1/1 vol). The stability of COL was enhanced by means of cross-linking with EDC and NHS at a molar ratio of 4:1. COL were exposed in culture medium for 21 days and human SAOS-2 human dermal fibroblasts and osteoblasts were cultured therein for 21 days as well.
Klíčová slova:
biodegradation; collagen; fibroblasts; mechanical properties; osteoblasts; structural properties Zdrojový dokument: Acta Polytechnica CTU Proceedings, ISBN 978-80-01-06670-6 Poznámka: Související webová stránka: https://ojs.cvut.cz/ojs/index.php/APP/article/view/6031/5306
Instituce: Ústav struktury a mechaniky hornin AV ČR
(web)
Informace o dostupnosti dokumentu:
Dokument je dostupný v příslušném ústavu Akademie věd ČR. Původní záznam: http://hdl.handle.net/11104/0313345